Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes C10orf90
  • Mouse genes D7Ertd443e
  • Rat genes LOC100302465
  • Zfish genes si:ch211-232h12.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set D7Ertd443e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042826	histone deacetylase binding	D7Ertd443e	IDA		Mouse	MGI:MGI:4455105|PMID:20154723
Molecular Function	GO:0005515	protein binding	D7Ertd443e	IPI	UniProtKB:P02340	Mouse	MGI:MGI:6201913|PMID:24240685
Molecular Function	GO:0061630	ubiquitin protein ligase activity	D7Ertd443e	IDA		Mouse	MGI:MGI:6201913|PMID:24240685
Cellular Component	GO:0015629	actin cytoskeleton	C10orf90	IDA		Human	PMID:20844083
Cellular Component	GO:0005813	centrosome	C10orf90	IDA		Human	PMID:20844083
Cellular Component	GO:0005737	cytoplasm	C10orf90	IDA		Human	PMID:20844083
Cellular Component	GO:0005829	cytosol	C10orf90	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	C10orf90	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	C10orf90	IDA		Human	GO_REF:0000052
Biological Process	GO:0006974	DNA damage response	D7Ertd443e	IDA		Mouse	MGI:MGI:4455105|PMID:20154723
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	D7Ertd443e	IDA		Mouse	MGI:MGI:4455105|PMID:20154723
Biological Process	GO:0030308	negative regulation of cell growth	D7Ertd443e	IDA		Mouse	MGI:MGI:5285148|PMID:20843368
Biological Process	GO:0000209	protein polyubiquitination	D7Ertd443e	IDA		Mouse	MGI:MGI:6201913|PMID:24240685
Biological Process	GO:0050821	protein stabilization	D7Ertd443e	IDA		Mouse	MGI:MGI:4455105|PMID:20154723
Biological Process	GO:0050821	protein stabilization	D7Ertd443e	IDA		Mouse	MGI:MGI:6201913|PMID:24240685
Biological Process	GO:0016567	protein ubiquitination	D7Ertd443e	IDA		Mouse	MGI:MGI:6201913|PMID:24240685
Biological Process	GO:0010212	response to ionizing radiation	D7Ertd443e	IDA		Mouse	MGI:MGI:4455105|PMID:20154723
Biological Process	GO:0009411	response to UV	D7Ertd443e	IDA		Mouse	MGI:MGI:5285148|PMID:20843368

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern