Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DAND5
  • Mouse genes Dand5
  • Rat genes Dand5
  • Zfish genes dand5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dand5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016015	morphogen activity	Dand5	IMP		Mouse	MGI:MGI:3055649|PMID:15466485
Molecular Function	GO:0005515	protein binding	Dand5	IPI	UniProtKB:Q91619	Mouse	MGI:MGI:3055649|PMID:15466485
Molecular Function	GO:0005515	protein binding	dand5	IPI	UniProtKB:Q7ZZT5	Zfish	PMID:15084459
Biological Process	GO:0003283	atrial septum development	Dand5	IMP		Mouse	MGI:MGI:3055649|PMID:15466485
Biological Process	GO:0061371	determination of heart left/right asymmetry	Dand5	IMP		Mouse	MGI:MGI:3055649|PMID:15466485
Biological Process	GO:0035462	determination of left/right asymmetry in diencephalon	dand5	IMP	ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:15084459
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	Dand5	IMP		Mouse	MGI:MGI:3055649|PMID:15466485
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	dand5	IMP	ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:15084459
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	dand5	IGI	ZFIN:ZDB-MRPHLNO-060112-1,ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:15084459
Biological Process	GO:0007368	determination of left/right symmetry	Dand5	IMP	MGI:MGI:3056132	Mouse	PMID:15466485
Biological Process	GO:0007368	determination of left/right symmetry	Dand5	IGI	MGI:MGI:97359	Mouse	PMID:15466485
Biological Process	GO:0007368	determination of left/right symmetry	dand5	IMP	ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:15084459
Biological Process	GO:0007368	determination of left/right symmetry	dand5	IMP	ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:18985756
Biological Process	GO:0035050	embryonic heart tube development	dand5	IMP	ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:15084459
Biological Process	GO:0001706	endoderm formation	dand5	IMP		Zfish	PMID:15084459
Biological Process	GO:0061966	establishment of left/right asymmetry	dand5	IGI	ZFIN:ZDB-GENO-190830-5	Zfish	PMID:30446628
Biological Process	GO:0061966	establishment of left/right asymmetry	dand5	IMP	ZFIN:ZDB-GENO-190830-3	Zfish	PMID:30446628
Biological Process	GO:0061966	establishment of left/right asymmetry	dand5	IGI	ZFIN:ZDB-GENO-190830-6	Zfish	PMID:30446628
Biological Process	GO:0061966	establishment of left/right asymmetry	dand5	IMP	ZFIN:ZDB-GENO-190830-4	Zfish	PMID:30446628
Biological Process	GO:0003146	heart jogging	dand5	IMP	ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:15084459
Biological Process	GO:0001947	heart looping	dand5	IMP	ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:15084459
Biological Process	GO:0001707	mesoderm formation	dand5	IMP		Zfish	PMID:15084459
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	dand5	IDA		Zfish	PMID:15084459
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	dand5	IMP	ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:15084459
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	Dand5	IDA		Mouse	MGI:MGI:3055649|PMID:15466485
Biological Process	GO:1900108	negative regulation of nodal signaling pathway	Dand5	IDA		Mouse	MGI:MGI:3055649|PMID:15466485
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Dand5	IGI	MGI:MGI:97359	Mouse	PMID:14721776
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	Dand5	IDA		Mouse	PMID:10208746
Biological Process	GO:0038101	sequestering of nodal from receptor via nodal binding	Dand5	IDA		Mouse	MGI:MGI:3055649|PMID:15466485
Biological Process	GO:0010084	specification of animal organ axis polarity	dand5	IMP	ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:15084459
Biological Process	GO:0003281	ventricular septum development	Dand5	IMP		Mouse	MGI:MGI:3055649|PMID:15466485

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern