Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DAP
  • Mouse genes Dap
  • Rat genes Dap
  • Zfish genes dap
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070513	death domain binding	DAP	IPI	UniProtKB:P19438	Human	PMID:1087798
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	DAP	IMP		Human	PMID:1087798
Biological Process	GO:0006915	apoptotic process	DAP	IGI	UniProtKB:P01579	Human	PMID:7828849
Biological Process	GO:0097190	apoptotic signaling pathway	DAP	IMP		Human	PMID:1087798
Biological Process	GO:0097190	apoptotic signaling pathway	DAP	IMP		Human	PMID:7828849
Biological Process	GO:0034198	cellular response to amino acid starvation	DAP	IDA		Human	PMID:20537536
Biological Process	GO:0010507	negative regulation of autophagy	DAP	IMP		Human	PMID:20537536
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	DAP	IMP		Human	PMID:1087798
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	DAP	IMP		Human	PMID:1087798

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern