Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DAPK3
  • Mouse genes Dapk3
  • Rat genes Dapk3
  • Zfish genes dapk3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dapk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	DAPK3	IDA		Human	PMID:10356987
Molecular Function	GO:0005524	ATP binding	Dapk3	IDA		Mouse	MGI:MGI:1196722|PMID:9488481
Molecular Function	GO:0005524	ATP binding	Dapk3	IDA		Rat	PMID:10602480|RGD:8554171
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Dapk3	IPI	RGD:70892	Rat	PMID:11884640|RGD:619664
Molecular Function	GO:0042802	identical protein binding	DAPK3	IPI	UniProtKB:O43293	Human	PMID:18239682
Molecular Function	GO:0042802	identical protein binding	DAPK3	IPI	UniProtKB:O43293	Human	PMID:21487036
Molecular Function	GO:0016301	kinase activity	Dapk3	IDA		Rat	PMID:10602480|RGD:8554171
Molecular Function	GO:0043522	leucine zipper domain binding	DAPK3	IPI	UniProtKB:Q9NY61	Human	PMID:10580117
Molecular Function	GO:0005515	protein binding	DAPK3	IPI	UniProtKB:O14974	Human	PMID:15292222
Molecular Function	GO:0005515	protein binding	DAPK3	IPI	UniProtKB:Q8TDR4	Human	PMID:15910542
Molecular Function	GO:0005515	protein binding	DAPK3	IPI	UniProtKB:Q9UBE8	Human	PMID:21454679
Molecular Function	GO:0005515	protein binding	DAPK3	IPI	UniProtKB:Q8TDR4	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	Dapk3	IPI	UniProtKB:P18848|UniProtKB:Q06507	Mouse	MGI:MGI:1196722|PMID:9488481
Molecular Function	GO:0005515	protein binding	Dapk3	IPI	UniProtKB:P61077	Mouse	MGI:MGI:3802861|PMID:18515077
Molecular Function	GO:0005515	protein binding	Dapk3	IPI	UniProtKB:P42227	Mouse	MGI:MGI:3610586|PMID:16219639
Molecular Function	GO:0005515	protein binding	Dapk3	IPI	UniProtKB:O35613|UniProtKB:Q06507|UniProtKB:Q925B0	Mouse	MGI:MGI:3687891|PMID:12917339
Molecular Function	GO:0005515	protein binding	Dapk3	IPI	RGD:69065	Rat	PMID:10602480|RGD:8554171
Molecular Function	GO:0005515	protein binding	Dapk3	IPI	UniProtKB:Q62627	Rat	PMID:10602480|RGD:8554171
Molecular Function	GO:0042803	protein homodimerization activity	DAPK3	IDA		Human	PMID:18239682
Molecular Function	GO:0004672	protein kinase activity	dapk3	IDA		Zfish	PMID:24983477
Molecular Function	GO:0004674	protein serine/threonine kinase activity	DAPK3	IDA		Human	PMID:10356987
Molecular Function	GO:0004674	protein serine/threonine kinase activity	DAPK3	IDA		Human	PMID:18239682
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Dapk3	IDA		Mouse	MGI:MGI:1196722|PMID:9488481
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Dapk3	IDA		Rat	PMID:10602480|RGD:8554171
Molecular Function	GO:0031267	small GTPase binding	DAPK3	IDA		Human	PMID:23454120
Cellular Component	GO:0005884	actin filament	Dapk3	IDA		Rat	PMID:10602480|RGD:8554171
Cellular Component	GO:0005737	cytoplasm	Dapk3	IDA		Rat	PMID:10602480|RGD:8554171
Cellular Component	GO:0005737	cytoplasm	dapk3	IDA		Zfish	PMID:17953487
Cellular Component	GO:0005737	cytoplasm	dapk3	IDA		Zfish	PMID:24983477
Cellular Component	GO:0005829	cytosol	DAPK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045121	membrane raft	Dapk3	IDA		Rat	PMID:21172653|RGD:8554227
Cellular Component	GO:0005654	nucleoplasm	DAPK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Dapk3	IDA		Mouse	MGI:MGI:1196722|PMID:9488481
Cellular Component	GO:0005634	nucleus	Dapk3	IDA		Rat	PMID:10602480|RGD:8554171
Cellular Component	GO:0005634	nucleus	dapk3	IDA		Zfish	PMID:17953487
Cellular Component	GO:0005634	nucleus	dapk3	IDA		Zfish	PMID:24983477
Cellular Component	GO:0016605	PML body	Dapk3	IDA		Mouse	PMID:12917339
Biological Process	GO:0006915	apoptotic process	DAPK3	IDA		Human	PMID:10580117
Biological Process	GO:0006915	apoptotic process	DAPK3	IMP		Human	PMID:12917339
Biological Process	GO:0006915	apoptotic process	Dapk3	IMP		Rat	PMID:10602480|RGD:8554171
Biological Process	GO:0097190	apoptotic signaling pathway	Dapk3	IGI	MGI:MGI:2149961	Mouse	PMID:12917339
Biological Process	GO:0097190	apoptotic signaling pathway	Dapk3	IGI	MGI:MGI:1197015	Mouse	PMID:12917339
Biological Process	GO:0097190	apoptotic signaling pathway	Dapk3	IDA		Mouse	PMID:9488481
Biological Process	GO:0071346	cellular response to type II interferon	DAPK3	IDA		Human	PMID:18995835
Biological Process	GO:0071346	cellular response to type II interferon	Dapk3	IMP		Mouse	MGI:MGI:5466658|PMID:23071094
Biological Process	GO:0035556	intracellular signal transduction	DAPK3	IDA		Human	PMID:10356987
Biological Process	GO:0035556	intracellular signal transduction	Dapk3	IDA		Mouse	MGI:MGI:1196722|PMID:9488481
Biological Process	GO:0035556	intracellular signal transduction	Dapk3	IDA		Rat	PMID:10602480|RGD:8554171
Biological Process	GO:0017148	negative regulation of translation	DAPK3	IDA		Human	PMID:18995835
Biological Process	GO:0030182	neuron differentiation	Dapk3	IEP		Rat	PMID:12445468|RGD:632627
Biological Process	GO:0043065	positive regulation of apoptotic process	DAPK3	IDA		Human	PMID:21487036
Biological Process	GO:0043065	positive regulation of apoptotic process	Dapk3	IDA		Rat	PMID:10602480|RGD:8554171
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	DAPK3	IMP		Human	PMID:21454679
Biological Process	GO:0030335	positive regulation of cell migration	Dapk3	IMP		Mouse	MGI:MGI:5582175|PMID:15096528
Biological Process	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Dapk3	IMP		Rat	PMID:21172653|RGD:8554227
Biological Process	GO:0046777	protein autophosphorylation	DAPK3	IDA		Human	PMID:18239682
Biological Process	GO:0006468	protein phosphorylation	DAPK3	IDA		Human	PMID:10356987
Biological Process	GO:0006468	protein phosphorylation	Dapk3	IDA		Mouse	MGI:MGI:1196722|PMID:9488481
Biological Process	GO:2000249	regulation of actin cytoskeleton reorganization	DAPK3	IDA		Human	PMID:23454120
Biological Process	GO:0008360	regulation of cell shape	Dapk3	IMP		Mouse	MGI:MGI:5582175|PMID:15096528
Biological Process	GO:0051893	regulation of focal adhesion assembly	DAPK3	IDA		Human	PMID:23454120
Biological Process	GO:0007346	regulation of mitotic cell cycle	DAPK3	IMP		Human	PMID:21487036
Biological Process	GO:0043519	regulation of myosin II filament organization	Dapk3	IMP		Mouse	MGI:MGI:5582175|PMID:15096528

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern