Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Dbh

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes DBH
- Mouse genes Dbh
- Rat genes Dbh
- Zfish genes dbh
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dbh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005507	copper ion binding	DBH	IDA		Human	PMID:27152332
Molecular Function	GO:0005507	copper ion binding	DBH	IDA		Human	PMID:7961964
Molecular Function	GO:0005507	copper ion binding	Dbh	IMP		Rat	PMID:10573542\|RGD:1625403
Molecular Function	GO:0004500	dopamine beta-monooxygenase activity	DBH	IDA		Human	PMID:3443096
Molecular Function	GO:0004500	dopamine beta-monooxygenase activity	DBH	IDA		Human	PMID:7961964
Molecular Function	GO:0004500	dopamine beta-monooxygenase activity	Dbh	IMP		Rat	PMID:11521740\|RGD:1625401
Molecular Function	GO:0004500	dopamine beta-monooxygenase activity	Dbh	IDA		Rat	PMID:15380000\|RGD:1625400
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q04656	Human	PMID:26199316
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:P00352	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:P08727	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:P27986-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:P61978	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:P63010-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q14693	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q6GQQ9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q71DI3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q86WT6-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q8IUW3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q8N6K7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q8WUW1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q92876	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q96D59	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q9GZS3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q9ULX5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q9UNS2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DBH	IPI	UniProtKB:Q9Y2M5	Human	PMID:32814053
Cellular Component	GO:0045177	apical part of cell	Dbh	IDA		Rat	PMID:20478367\|RGD:5129236
Cellular Component	GO:0030424	axon	Dbh	IDA		Rat	PMID:15380000\|RGD:1625400
Cellular Component	GO:0034451	centriolar satellite	DBH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	Dbh	IDA		Rat	PMID:20478367\|RGD:5129236
Cellular Component	GO:0031410	cytoplasmic vesicle	Dbh	IDA		Rat	PMID:18499388\|RGD:5130740
Cellular Component	GO:0030425	dendrite	Dbh	IDA		Rat	PMID:17572158\|RGD:5130209
Cellular Component	GO:0005783	endoplasmic reticulum	DBH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	DBH	IDA		Human	PMID:7961964
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	DBH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043025	neuronal cell body	Dbh	IDA		Rat	PMID:18440151\|RGD:2304273
Cellular Component	GO:0034774	secretory granule lumen	DBH	IDA		Human	PMID:7961964
Cellular Component	GO:0034774	secretory granule lumen	Dbh	IDA		Mouse	MGI:MGI:5785000\|PMID:7961964
Cellular Component	GO:0030667	secretory granule membrane	DBH	IDA		Human	PMID:7961964
Cellular Component	GO:0030667	secretory granule membrane	Dbh	IDA		Mouse	MGI:MGI:5785000\|PMID:7961964
Cellular Component	GO:0045202	synapse	Dbh	IDA		Rat	PMID:21145919\|RGD:5129206
Cellular Component	GO:0043195	terminal bouton	Dbh	IDA		Rat	PMID:19651110\|RGD:5129482
Cellular Component	GO:0043196	varicosity	Dbh	IDA		Rat	PMID:19651110\|RGD:5129482
Biological Process	GO:0008306	associative learning	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:9189272
Biological Process	GO:0048149	behavioral response to ethanol	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:10777779
Biological Process	GO:0001974	blood vessel remodeling	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:15231500
Biological Process	GO:0001974	blood vessel remodeling	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:15849236
Biological Process	GO:0060348	bone development	Dbh	IEP		Rat	PMID:20090303\|RGD:5129678
Biological Process	GO:0071287	cellular response to manganese ion	Dbh	IEP		Rat	PMID:19276553\|RGD:5129515
Biological Process	GO:0071316	cellular response to nicotine	Dbh	IEP		Rat	PMID:20827341\|RGD:5129209
Biological Process	GO:0001816	cytokine production	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:10051631
Biological Process	GO:0042420	dopamine catabolic process	DBH	IDA		Human	PMID:3443096
Biological Process	GO:0042420	dopamine catabolic process	DBH	IDA		Human	PMID:7961964
Biological Process	GO:0042420	dopamine catabolic process	Dbh	IMP		Mouse	MGI:MGI:5787847\|PMID:27148966
Biological Process	GO:0042420	dopamine catabolic process	Dbh	IMP		Mouse	MGI:MGI:72180\|PMID:7715704
Biological Process	GO:0042420	dopamine catabolic process	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:10051631
Biological Process	GO:0042596	fear response	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:15066288
Biological Process	GO:0042593	glucose homeostasis	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:12959968
Biological Process	GO:0042593	glucose homeostasis	Dbh	IMP		Rat	PMID:19129404\|RGD:5129518
Biological Process	GO:0042309	homoiothermy	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:9139828
Biological Process	GO:0002443	leukocyte mediated immunity	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:10051631
Biological Process	GO:0050900	leukocyte migration	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:15849236
Biological Process	GO:0007626	locomotory behavior	Dbh	IMP		Mouse	MGI:MGI:5787847\|PMID:27148966
Biological Process	GO:0007626	locomotory behavior	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:9189272
Biological Process	GO:0042711	maternal behavior	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:9393852
Biological Process	GO:0007613	memory	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:9189272
Biological Process	GO:0007613	memory	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:15066288
Biological Process	GO:0010259	multicellular organism aging	Dbh	IEP		Rat	PMID:18522866\|RGD:5129682
Biological Process	GO:0042421	norepinephrine biosynthetic process	DBH	IMP		Human	PMID:27148966
Biological Process	GO:0042421	norepinephrine biosynthetic process	Dbh	IMP		Mouse	MGI:MGI:5787847\|PMID:27148966
Biological Process	GO:0042421	norepinephrine biosynthetic process	Dbh	IMP		Mouse	MGI:MGI:72180\|PMID:7715704
Biological Process	GO:0042421	norepinephrine biosynthetic process	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:9603211
Biological Process	GO:0042421	norepinephrine biosynthetic process	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:10051631
Biological Process	GO:0042421	norepinephrine biosynthetic process	Dbh	IMP		Rat	PMID:10573542\|RGD:1625403
Biological Process	GO:0046333	octopamine metabolic process	Dbh	IMP		Rat	PMID:11521740\|RGD:1625401
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Dbh	IMP		Mouse	MGI:MGI:87391\|PMID:9139828
Biological Process	GO:0045907	positive regulation of vasoconstriction	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:9139828
Biological Process	GO:2001236	regulation of extrinsic apoptotic signaling pathway	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:15849236
Biological Process	GO:1904705	regulation of vascular associated smooth muscle cell proliferation	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:15849236
Biological Process	GO:1905562	regulation of vascular endothelial cell proliferation	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:15849236
Biological Process	GO:0001975	response to amphetamine	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:12370425
Biological Process	GO:0046688	response to copper ion	Dbh	IEP		Rat	PMID:19079842\|RGD:5129530
Biological Process	GO:0032355	response to estradiol	Dbh	IEP		Rat	PMID:11914591\|RGD:727567
Biological Process	GO:0045471	response to ethanol	Dbh	IEP		Rat	PMID:16713504\|RGD:5130703
Biological Process	GO:0035902	response to immobilization stress	Dbh	IEP		Rat	PMID:19893991\|RGD:9684986
Biological Process	GO:0010039	response to iron ion	Dbh	IEP		Rat	PMID:18363828\|RGD:5129689
Biological Process	GO:0035900	response to isolation stress	Dbh	IEP		Rat	PMID:19893991\|RGD:9684986
Biological Process	GO:0014070	response to organic cyclic compound	Dbh	IEP		Rat	PMID:18783367\|RGD:5129680
Biological Process	GO:0010193	response to ozone	Dbh	IEP		Rat	PMID:19356678\|RGD:5129483
Biological Process	GO:0048265	response to pain	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:11805341
Biological Process	GO:0043434	response to peptide hormone	Dbh	IEP		Rat	PMID:18522866\|RGD:5129682
Biological Process	GO:0009410	response to xenobiotic stimulus	Dbh	IEP		Rat	PMID:20626387\|RGD:5129233
Biological Process	GO:0050909	sensory perception of taste	Dbh	IEP		Rat	PMID:20478367\|RGD:5129236
Biological Process	GO:0030431	sleep	dbh	IMP	ZFIN:ZDB-GENO-131125-13	Zfish	PMID:26374985
Biological Process	GO:0030431	sleep	dbh	IGI	ZFIN:ZDB-GENE-040324-1	Zfish	PMID:26374985
Biological Process	GO:0035176	social behavior	Dbh	IEP		Rat	PMID:15345906\|RGD:5130765
Biological Process	GO:0042310	vasoconstriction	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:9139828
Biological Process	GO:0008542	visual learning	Dbh	IMP	MGI:MGI:1857556	Mouse	PMID:9189272

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.