Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DBT
  • Mouse genes Dbt
  • Rat genes Dbt
  • Zfish genes dbt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dbt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031625	ubiquitin protein ligase binding	DBT	IPI	UniProtKB:O60260	Human	PMID:19725078
Cellular Component	GO:0005829	cytosol	DBT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015630	microtubule cytoskeleton	DBT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex	DBT	IPI		Human	PMID:3593587
Cellular Component	GO:0042645	mitochondrial nucleoid	DBT	IDA		Human	PMID:18063578
Cellular Component	GO:0005739	mitochondrion	DBT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Dbt	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Dbt	HDA		Mouse	PMID:18614015
Biological Process	GO:0009083	branched-chain amino acid catabolic process	DBT	IDA		Human	PMID:3593587
Biological Process	GO:0009081	branched-chain amino acid metabolic process	dbt	IMP	ZFIN:ZDB-GENO-980202-811	Zfish	PMID:22046030

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern