Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCAF1
  • Mouse genes Dcaf1
  • Rat genes Dcaf1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dcaf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990244	histone H2AT120 kinase activity	DCAF1	IDA		Human	PMID:24140421
Molecular Function	GO:0030331	nuclear estrogen receptor binding	DCAF1	IPI	UniProtKB:P03372	Human	PMID:28068668
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:Q13619,UniProtKB:Q13620,UniProtKB:Q16531	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:P18045	Human	PMID:19264781
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:P19508	Human	PMID:19264781
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:P35240	Human	PMID:20178741
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:Q16531	Human	PMID:22157821
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:P12520	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:P19508	Human	PMID:24336198
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:Q16531	Human	PMID:24412650
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:O95835	Human	PMID:25026211
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:Q9NRM7	Human	PMID:25026211
Molecular Function	GO:0005515	protein binding	DCAF1	IPI	UniProtKB:A0A0H3LAC5	Human	PMID:30118682
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	DCAF1	IDA		Human	PMID:23063525
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	DCAF1	IDA		Human	PMID:16949367
Cellular Component	GO:0001650	fibrillar center	DCAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DCAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DCAF1	IDA		Human	PMID:20178741
Biological Process	GO:0030183	B cell differentiation	Dcaf1	IMP		Mouse	MGI:MGI:5314150|PMID:22157821
Biological Process	GO:0035212	cell competition in a multicellular organism	DCAF1	IMP		Human	PMID:20644714
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	DCAF1	IDA		Human	PMID:24140421
Biological Process	GO:0045732	positive regulation of protein catabolic process	DCAF1	IDA		Human	PMID:23063525
Biological Process	GO:0043687	post-translational protein modification	DCAF1	IDA		Human	PMID:24140421
Biological Process	GO:0033151	V(D)J recombination	Dcaf1	IMP		Mouse	MGI:MGI:5314150|PMID:22157821

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern