Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCAF8
  • Mouse genes Dcaf8
  • Rat genes Dcaf8
  • Zfish genes dcaf8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dcaf8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q99750	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q13619,UniProtKB:Q13620,UniProtKB:Q16531	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q99750	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q16531	Human	PMID:19966799
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:P12520	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:O14980	Human	PMID:22500989
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:P52294	Human	PMID:22500989
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q14974	Human	PMID:22500989
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:O43463	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q99873	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q16531	Human	PMID:24500646
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q93062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q99750	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q9NVV9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q16531	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q16531	Human	PMID:31391242
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q969Q1	Human	PMID:31391242
Molecular Function	GO:0005515	protein binding	DCAF8	IPI	UniProtKB:Q9BYV2	Human	PMID:31391242
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	DCAF8	IDA		Human	PMID:16949367
Cellular Component	GO:0005737	cytoplasm	DCAF8	IDA		Human	PMID:22500989
Cellular Component	GO:0005829	cytosol	DCAF8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	DCAF8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DCAF8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DCAF8	IDA		Human	PMID:22500989
Biological Process	GO:0021782	glial cell development	dcaf8	IMP	ZFIN:ZDB-CRISPR-191009-23,ZFIN:ZDB-CRISPR-191009-24	Zfish	PMID:30924555
Biological Process	GO:0060041	retina development in camera-type eye	dcaf8	IMP	ZFIN:ZDB-CRISPR-191009-23,ZFIN:ZDB-CRISPR-191009-24	Zfish	PMID:30924555

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern