Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCK
  • Mouse genes Dck
  • Rat genes Dck
  • Zfish genes dck
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dck

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Dck	IDA		Rat	PMID:8305745|RGD:2300395
Molecular Function	GO:0043771	cytidine kinase activity	DCK	IDA		Human	PMID:34768989
Molecular Function	GO:0004136	deoxyadenosine kinase activity	DCK	IDA		Human	PMID:34768989
Molecular Function	GO:0004136	deoxyadenosine kinase activity	Dck	IMP		Mouse	PMID:8748457
Molecular Function	GO:0004137	deoxycytidine kinase activity	DCK	IDA		Human	PMID:12808445
Molecular Function	GO:0004137	deoxycytidine kinase activity	DCK	IDA		Human	PMID:20637175
Molecular Function	GO:0004137	deoxycytidine kinase activity	DCK	IDA		Human	PMID:34768989
Molecular Function	GO:0004137	deoxycytidine kinase activity	Dck	IMP		Rat	PMID:7686601|RGD:2300398
Molecular Function	GO:0004137	deoxycytidine kinase activity	Dck	IDA		Rat	PMID:8305745|RGD:2300395
Molecular Function	GO:0004138	deoxyguanosine kinase activity	DCK	IDA		Human	PMID:2539852
Molecular Function	GO:0004138	deoxyguanosine kinase activity	DCK	IDA		Human	PMID:34768989
Molecular Function	GO:0032546	deoxyribonucleoside binding	Dck	IPI	CHEBI:28680|CHEBI:50131	Rat	PMID:7532033|RGD:2300399
Molecular Function	GO:0000287	magnesium ion binding	Dck	IDA		Rat	PMID:8305745|RGD:2300395
Molecular Function	GO:0042803	protein homodimerization activity	DCK	IPI	UniProtKB:P27707	Human	PMID:12808445
Molecular Function	GO:0032548	pyrimidine deoxyribonucleoside binding	Dck	IMP		Rat	PMID:7686601|RGD:2300398
Molecular Function	GO:0032548	pyrimidine deoxyribonucleoside binding	Dck	IDA		Rat	PMID:8305745|RGD:2300395
Cellular Component	GO:0005829	cytosol	Dck	IDA		Rat	PMID:8305745|RGD:2300395
Cellular Component	GO:0005654	nucleoplasm	DCK	IDA		Human	GO_REF:0000052
Biological Process	GO:0106383	dAMP salvage	Dck	IMP		Mouse	PMID:8748457
Biological Process	GO:0046092	deoxycytidine metabolic process	Dck	IMP		Rat	PMID:7686601|RGD:2300398
Biological Process	GO:0046092	deoxycytidine metabolic process	Dck	IDA		Rat	PMID:8305745|RGD:2300395
Biological Process	GO:1901293	nucleoside phosphate biosynthetic process	DCK	IDA		Human	PMID:34768989
Biological Process	GO:0006220	pyrimidine nucleotide metabolic process	DCK	IDA		Human	PMID:12808445

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern