Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCLK2
  • Mouse genes Dclk2
  • Rat genes Dclk2
  • Zfish genes dclk2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dclk2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008017	microtubule binding	Dclk2	IDA		Mouse	PMID:16684769
Molecular Function	GO:0005515	protein binding	DCLK2	IPI	UniProtKB:Q96M94	Human	PMID:33199366
Molecular Function	GO:0005515	protein binding	dclk2a	IPI	UniProtKB:B0UXI4	Zfish	PMID:20097902|ZFIN:ZDB-PUB-100126-16
Molecular Function	GO:0005515	protein binding	dclk2a	IPI	UniProtKB:C5NU62	Zfish	PMID:20097902|ZFIN:ZDB-PUB-100126-16
Molecular Function	GO:0005515	protein binding	dclk2a	IPI	UniProtKB:P02687	Zfish	PMID:20097902|ZFIN:ZDB-PUB-100126-16
Molecular Function	GO:0004672	protein kinase activity	Dclk2	IDA		Mouse	PMID:16684769
Molecular Function	GO:0004672	protein kinase activity	dclk2a	IDA		Zfish	PMID:17498644
Molecular Function	GO:0004674	protein serine/threonine kinase activity	dclk2a	IDA		Zfish	PMID:20097902
Cellular Component	GO:0005737	cytoplasm	dclk2a	IDA		Zfish	PMID:17498644
Cellular Component	GO:0015630	microtubule cytoskeleton	dclk2a	IDA		Zfish	PMID:17498644
Cellular Component	GO:0005634	nucleus	dclk2a	IDA		Zfish	PMID:24582561
Cellular Component	GO:0008021	synaptic vesicle	dclk2a	IDA		Zfish	PMID:20097902
Biological Process	GO:0021766	hippocampus development	Dclk2	IGI	MGI:MGI:1277171	Mouse	PMID:19342486
Biological Process	GO:0006972	hyperosmotic response	dclk2a	IDA		Zfish	PMID:24582561
Biological Process	GO:0000226	microtubule cytoskeleton organization	Dclk2	IDA		Mouse	PMID:16684769
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	Dclk2	IDA		Mouse	PMID:16684769
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Dclk2	IDA		Mouse	PMID:16684769
Biological Process	GO:0046777	protein autophosphorylation	dclk2a	IDA		Zfish	PMID:24582561
Biological Process	GO:0046777	protein autophosphorylation	dclk2a	IDA		Zfish	PMID:17498644
Biological Process	GO:0034504	protein localization to nucleus	Dclk2	IDA		Mouse	PMID:16684769
Biological Process	GO:0006468	protein phosphorylation	dclk2a	IDA		Zfish	PMID:20097902
Biological Process	GO:0006468	protein phosphorylation	dclk2a	IPI	ZFIN:ZDB-GENE-040718-197	Zfish	PMID:24582561
Biological Process	GO:0021860	pyramidal neuron development	Dclk2	IGI	MGI:MGI:1277171	Mouse	PMID:19342486

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern