Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCST1
  • Mouse genes Dcst1
  • Rat genes Dcst1
  • Zfish genes dcst1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dcst1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DCST1	IPI	UniProtKB:P52630	Human	PMID:27782195
Molecular Function	GO:0061630	ubiquitin protein ligase activity	DCST1	IDA		Human	PMID:27782195
Cellular Component	GO:0005886	plasma membrane	DCST1	IDA		Human	PMID:27782195
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	Dcst1	IMP		Mouse	MGI:MGI:6694748|PMID:33871360
Biological Process	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	DCST1	IMP		Human	PMID:27782195
Biological Process	GO:0009612	response to mechanical stimulus	dcst1	IDA		Zfish	PMID:23632157
Biological Process	GO:0035036	sperm-egg recognition	Dcst1	IMP		Mouse	MGI:MGI:6694748|PMID:33871360
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	DCST1	IMP		Human	PMID:27782195

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern