Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCSTAMP
  • Mouse genes Dcstamp
  • Rat genes Dcstamp
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dcstamp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DCSTAMP	IPI	UniProtKB:O43889-2	Human	PMID:20546900
Molecular Function	GO:0005515	protein binding	DCSTAMP	IPI	UniProtKB:Q13438	Human	PMID:20546900
Cellular Component	GO:0009986	cell surface	DCSTAMP	IDA		Human	PMID:11169400
Cellular Component	GO:0009986	cell surface	Dcstamp	IDA		Mouse	MGI:MGI:3510294|PMID:15452179
Cellular Component	GO:0005789	endoplasmic reticulum membrane	DCSTAMP	IDA		Human	PMID:15601667
Cellular Component	GO:0005789	endoplasmic reticulum membrane	DCSTAMP	IDA		Human	PMID:20546900
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Dcstamp	IDA		Mouse	MGI:MGI:3812293|PMID:18653699
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Dcstamp	IDA		Mouse	MGI:MGI:5319771|PMID:15601667
Cellular Component	GO:0010008	endosome membrane	Dcstamp	IDA		Mouse	MGI:MGI:3812293|PMID:18653699
Biological Process	GO:0071353	cellular response to interleukin-4	DCSTAMP	IDA		Human	PMID:15601667
Biological Process	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	Dcstamp	IDA		Mouse	MGI:MGI:3588832|PMID:16061724
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Dcstamp	IEP		Rat	PMID:23110133|RGD:151665477
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Dcstamp	IDA		Mouse	MGI:MGI:3588832|PMID:16061724
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Dcstamp	IEP		Rat	PMID:23110133|RGD:151665477
Biological Process	GO:0061025	membrane fusion	Dcstamp	IMP		Mouse	MGI:MGI:5426135|PMID:16937266
Biological Process	GO:0061025	membrane fusion	Dcstamp	IDA		Mouse	MGI:MGI:3588832|PMID:16061724
Biological Process	GO:0061025	membrane fusion	Dcstamp	IMP		Mouse	MGI:MGI:5426134|PMID:17164993
Biological Process	GO:1903131	mononuclear cell differentiation	Dcstamp	IEP		Rat	PMID:23110133|RGD:151665477
Biological Process	GO:0043011	myeloid dendritic cell differentiation	Dcstamp	IDA		Mouse	MGI:MGI:5319610|PMID:17713547
Biological Process	GO:0030308	negative regulation of cell growth	Dcstamp	IDA		Mouse	MGI:MGI:5319610|PMID:17713547
Biological Process	GO:0030316	osteoclast differentiation	Dcstamp	IMP		Mouse	MGI:MGI:3510294|PMID:15452179
Biological Process	GO:0072675	osteoclast fusion	Dcstamp	IMP		Mouse	MGI:MGI:5426134|PMID:17164993
Biological Process	GO:0072675	osteoclast fusion	Dcstamp	IDA		Mouse	MGI:MGI:5426135|PMID:16937266
Biological Process	GO:0072675	osteoclast fusion	Dcstamp	IDA		Mouse	MGI:MGI:3588832|PMID:16061724
Biological Process	GO:0072675	osteoclast fusion	Dcstamp	IDA		Mouse	PMID:23980096
Biological Process	GO:0045780	positive regulation of bone resorption	Dcstamp	IMP		Mouse	MGI:MGI:5426135|PMID:16937266
Biological Process	GO:0045780	positive regulation of bone resorption	Dcstamp	IMP		Mouse	MGI:MGI:5426134|PMID:17164993
Biological Process	GO:0045780	positive regulation of bone resorption	Dcstamp	IMP		Mouse	MGI:MGI:3588832|PMID:16061724
Biological Process	GO:0034241	positive regulation of macrophage fusion	Dcstamp	IDA		Mouse	MGI:MGI:5426135|PMID:16937266
Biological Process	GO:0034241	positive regulation of macrophage fusion	Dcstamp	IMP		Mouse	MGI:MGI:3588832|PMID:16061724
Biological Process	GO:0034241	positive regulation of macrophage fusion	Dcstamp	IGI	MGI:MGI:1921864	Mouse	PMID:22865856
Biological Process	GO:0045657	positive regulation of monocyte differentiation	Dcstamp	IDA		Mouse	MGI:MGI:5319610|PMID:17713547

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern