Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCT
  • Mouse genes Dct
  • Rat genes
  • Zfish genes dct
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dct

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004167	dopachrome isomerase activity	Dct	IDA		Mouse	MGI:MGI:3690794|PMID:2169885
Molecular Function	GO:0004167	dopachrome isomerase activity	Dct	IMP	MGI:MGI:1856379	Mouse	PMID:1537334
Molecular Function	GO:0005515	protein binding	DCT	IPI	UniProtKB:P14679	Human	PMID:28842328
Molecular Function	GO:0005515	protein binding	DCT	IPI	UniProtKB:P60201-2	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Dct	IDA		Mouse	MGI:MGI:5049797|PMID:21610032
Cellular Component	GO:0005829	cytosol	Dct	IDA		Mouse	MGI:MGI:3690794|PMID:2169885
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	DCT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0042470	melanosome	Dct	IDA		Mouse	MGI:MGI:5755324|PMID:26620560
Cellular Component	GO:0042470	melanosome	Dct	IDA		Mouse	MGI:MGI:3690794|PMID:2169885
Cellular Component	GO:0005886	plasma membrane	DCT	IDA		Human	GO_REF:0000052
Biological Process	GO:0048468	cell development	Dct	IMP	MGI:MGI:1856379	Mouse	PMID:15060160
Biological Process	GO:0048066	developmental pigmentation	Dct	IMP	MGI:MGI:1856379	Mouse	PMID:15060160
Biological Process	GO:0042438	melanin biosynthetic process	Dct	IMP	MGI:MGI:1856379	Mouse	PMID:7665913
Biological Process	GO:0006583	melanin biosynthetic process from tyrosine	Dct	IMP		Mouse	MGI:MGI:6827472|PMID:33100333
Biological Process	GO:0006583	melanin biosynthetic process from tyrosine	Dct	IDA		Mouse	MGI:MGI:3690794|PMID:2169885
Biological Process	GO:0006582	melanin metabolic process	dct	IMP	ZFIN:ZDB-MRPHLNO-211201-4	Zfish	PMID:33100333
Biological Process	GO:0007405	neuroblast proliferation	Dct	IMP		Mouse	PMID:16857183
Biological Process	GO:0043473	pigmentation	Dct	IMP	MGI:MGI:1856379	Mouse	PMID:1537334
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Dct	IMP		Mouse	PMID:16857183
Biological Process	GO:0009637	response to blue light	DCT	IDA		Human	PMID:28842328
Biological Process	GO:0021847	ventricular zone neuroblast division	Dct	IMP		Mouse	PMID:16857183

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern