Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCX
  • Mouse genes Dcx
  • Rat genes Dcx
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dcx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008017	microtubule binding	DCX	IDA		Human	PMID:14741102
Molecular Function	GO:0008017	microtubule binding	DCX	IMP		Human	PMID:27292316
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q08379	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q13422	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q93008	Human	PMID:24607389
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:O15062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:P36406	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:P50221	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q13137	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q13422	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q6NUQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q96R06	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q9UJV3-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DCX	IPI	UniProtKB:Q6NUQ1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Dcx	IPI	UniProtKB:Q96M94	Mouse	MGI:MGI:7327227|PMID:33199366
Molecular Function	GO:0005515	protein binding	Dcx	IPI	PR:Q6R891	Mouse	PMID:14550532
Molecular Function	GO:0019901	protein kinase binding	DCX	IPI	UniProtKB:O08679	Human	PMID:14741102
Cellular Component	GO:0030424	axon	Dcx	IDA		Rat	PMID:22649224|RGD:12904752
Cellular Component	GO:0005737	cytoplasm	Dcx	IDA		Mouse	PMID:25209608
Cellular Component	GO:0005737	cytoplasm	Dcx	IDA		Mouse	PMID:23447615
Cellular Component	GO:0030425	dendrite	Dcx	IDA		Rat	PMID:19499587|RGD:2317769
Cellular Component	GO:0030426	growth cone	Dcx	IDA		Rat	PMID:19726658|RGD:12904759
Cellular Component	GO:0005874	microtubule	Dcx	IDA		Rat	PMID:19726658|RGD:12904759
Cellular Component	GO:0043005	neuron projection	DCX	IDA		Human	PMID:14741102
Cellular Component	GO:0043005	neuron projection	Dcx	IDA		Mouse	PMID:23861879
Cellular Component	GO:0043005	neuron projection	Dcx	IDA		Mouse	PMID:24367100
Cellular Component	GO:0043025	neuronal cell body	Dcx	IDA		Rat	PMID:19726658|RGD:12904759
Biological Process	GO:0048675	axon extension	Dcx	IGI	MGI:MGI:1330861	Mouse	PMID:16387638
Biological Process	GO:0007420	brain development	Dcx	IGI	MGI:MGI:1330861	Mouse	PMID:16387638
Biological Process	GO:0007420	brain development	Dcx	IEP		Rat	PMID:23690918|RGD:12904751
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Dcx	IGI	MGI:MGI:1330861	Mouse	PMID:16387638
Biological Process	GO:0048813	dendrite morphogenesis	Dcx	IGI	MGI:MGI:2652818	Mouse	PMID:21689730
Biological Process	GO:0048813	dendrite morphogenesis	Dcx	IGI	MGI:MGI:1330861	Mouse	PMID:16387638
Biological Process	GO:0021766	hippocampus development	Dcx	IGI	MGI:MGI:1918012	Mouse	PMID:19342486
Biological Process	GO:0021766	hippocampus development	Dcx	IMP	MGI:MGI:2387757	Mouse	PMID:19342486
Biological Process	GO:0021819	layer formation in cerebral cortex	Dcx	IMP	MGI:MGI:2387757	Mouse	PMID:19342486
Biological Process	GO:0001764	neuron migration	DCX	IDA		Human	PMID:14741102
Biological Process	GO:0001764	neuron migration	Dcx	IGI	MGI:MGI:1330861	Mouse	PMID:16387638
Biological Process	GO:0001764	neuron migration	Dcx	IGI	MGI:MGI:1330861	Mouse	PMID:16387639
Biological Process	GO:0001764	neuron migration	Dcx	IGI	MGI:MGI:2652818	Mouse	PMID:21689730
Biological Process	GO:0001764	neuron migration	Dcx	IMP		Rat	PMID:14625554|RGD:1304461
Biological Process	GO:0048672	positive regulation of collateral sprouting	Dcx	IMP		Rat	PMID:19726658|RGD:12904759
Biological Process	GO:0045807	positive regulation of endocytosis	Dcx	IMP		Rat	PMID:22649224|RGD:12904752
Biological Process	GO:0021860	pyramidal neuron development	Dcx	IGI	MGI:MGI:1918012	Mouse	PMID:19342486
Biological Process	GO:0051602	response to electrical stimulus	Dcx	IEP		Rat	PMID:19499587|RGD:2317769
Biological Process	GO:0021510	spinal cord development	Dcx	IEP		Rat	PMID:25487013|RGD:12904756

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern