Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDB1
  • Mouse genes Ddb1
  • Rat genes Ddb1
  • Zfish genes ddb1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097602	cullin family protein binding	DDB1	IDA		Human	PMID:10585395
Molecular Function	GO:0097602	cullin family protein binding	DDB1	IPI	UniProtKB:Q13619	Human	PMID:14739464
Molecular Function	GO:0003684	damaged DNA binding	DDB1	IDA		Human	PMID:22334663
Molecular Function	GO:0003684	damaged DNA binding	Ddb1	IMP		Rat	PMID:12145536|RGD:632554
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13216	Human	PMID:12732143
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:12732143
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619	Human	PMID:14739464
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q7L5Y6	Human	PMID:14739464
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:P11207	Human	PMID:16227264
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619	Human	PMID:16473935
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:16473935
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13216,UniProtKB:Q13619	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q13620,UniProtKB:Q58WW2	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q13620,UniProtKB:Q5H9S7	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q13620,UniProtKB:Q5TAQ9	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q13620,UniProtKB:Q8TEB1	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q13620,UniProtKB:Q92466	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q13620,UniProtKB:Q9BW61	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q13620,UniProtKB:Q9Y4B6	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q66K64	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q7L5Y6	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q96JK2	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q9NXF7	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q9NZJ0	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q16531	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q8N5D0	Human	PMID:16964240
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:O75530	Human	PMID:17041588
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q04725	Human	PMID:17041588
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619	Human	PMID:17041588
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13620	Human	PMID:17041588
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:17041588
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9NZJ0	Human	PMID:17041588
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9Y4B6-3	Human	PMID:17314515
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q72500	Human	PMID:17360488
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:17360488
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9UKV8	Human	PMID:17932509
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9UL18	Human	PMID:17932509
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q8TEB1	Human	PMID:19109893
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:19109893
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:P18045	Human	PMID:19264781
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13620	Human	PMID:19651607
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:P11207	Human	PMID:19966799
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619	Human	PMID:19966799
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q5TAQ9	Human	PMID:19966799
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q89246	Human	PMID:19966799
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q8N5D0-4	Human	PMID:19966799
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q8WV16	Human	PMID:19966799
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:19966799
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9QMH9	Human	PMID:19966799
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q96SW2	Human	PMID:20223979
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9BW61	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9H9F9	Human	PMID:20855601
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9ULG1	Human	PMID:20855601
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619	Human	PMID:21113133
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13620	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:P42224	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:22039351
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619	Human	PMID:22157821
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9Y4B6	Human	PMID:22157821
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:P11207	Human	PMID:22810585
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:22822215
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:O75530	Human	PMID:23238014
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13620	Human	PMID:23238014
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q969U6-1	Human	PMID:23314863
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q96SW2-2	Human	PMID:24292623
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9Y4B6	Human	PMID:24412650
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q5TAQ9	Human	PMID:24500646
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q96SW2	Human	PMID:26131937
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13620	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q6PH85	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q8IWE4	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q96GG9	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9BTE7	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q96SW2	Human	PMID:26909574
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q14498,UniProtKB:Q66K64	Human	PMID:28437394
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q5TAQ9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q8N5D0-4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q8TEB1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q8WV16	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q96JM7	Human	PMID:29691401
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9NV06	Human	PMID:30111536
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q9BW61	Human	PMID:30564455
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13619	Human	PMID:30945288
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q13620	Human	PMID:30945288
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q8WV16	Human	PMID:30945288
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q5TAQ9	Human	PMID:31391242
Molecular Function	GO:0005515	protein binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:9418871
Molecular Function	GO:0005515	protein binding	Ddb1	IPI	UniProtKB:P48432	Mouse	MGI:MGI:7387162|PMID:30442713
Molecular Function	GO:0005515	protein binding	Ddb1	IPI	UniProtKB:Q6PAC3	Mouse	MGI:MGI:6202868|PMID:30111536
Molecular Function	GO:0005515	protein binding	Ddb1	IPI	UniProtKB:P97784|UniProtKB:Q9R194	Mouse	MGI:MGI:6253084|PMID:27123980
Molecular Function	GO:0005515	protein binding	Ddb1	IPI	UniProtKB:O08785	Mouse	MGI:MGI:5919179|PMID:26323038
Molecular Function	GO:0005515	protein binding	Ddb1	IPI	UniProtKB:Q923J1	Mouse	MGI:MGI:5644004|PMID:24855944
Molecular Function	GO:0044877	protein-containing complex binding	DDB1	IPI	ComplexPortal:CPX-900	Human	PMID:11564863
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	DDB1	IPI	UniProtKB:Q13619,UniProtKB:Q7L5Y6	Human	PMID:14739464
Molecular Function	GO:0071987	WD40-repeat domain binding	DDB1	IPI	UniProtKB:Q13216	Human	PMID:16949367
Molecular Function	GO:0071987	WD40-repeat domain binding	DDB1	IPI	UniProtKB:Q16531	Human	PMID:16949367
Molecular Function	GO:0071987	WD40-repeat domain binding	DDB1	IPI	UniProtKB:Q5T6F0	Human	PMID:16949367
Molecular Function	GO:0071987	WD40-repeat domain binding	DDB1	IPI	UniProtKB:Q92466	Human	PMID:16949367
Molecular Function	GO:0071987	WD40-repeat domain binding	DDB1	IPI	UniProtKB:Q9NZJ0	Human	PMID:16949367
Cellular Component	GO:0000781	chromosome, telomeric region	DDB1	HDA		Human	PMID:19135898
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	DDB1	IMP		Human	PMID:16949367
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:18381890
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:28886238
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:31492966
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:31686031
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	Ddb1	IDA		Mouse	MGI:MGI:6454628|PMID:31492966
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	DDB1	EXP		Human	PMID:22118460
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:12732143
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:14739464
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:18794347
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:20129063
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:20223979
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	Ddb1	EXP		Mouse	MGI:MGI:6867266|PMID:22118460
Cellular Component	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:18794347
Cellular Component	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:21628527
Cellular Component	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	DDB1	IDA		Human	PMID:22334663
Cellular Component	GO:0005737	cytoplasm	DDB1	IDA		Human	PMID:18593899
Cellular Component	GO:0005737	cytoplasm	DDB1	IDA		Human	PMID:20223979
Cellular Component	GO:0005737	cytoplasm	DDB1	IDA		Human	PMID:23137809
Cellular Component	GO:0070062	extracellular exosome	DDB1	HDA		Human	PMID:19056867
Cellular Component	GO:0005615	extracellular space	DDB1	HDA		Human	PMID:22664934
Cellular Component	GO:0005654	nucleoplasm	DDB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DDB1	IDA		Human	PMID:10585395
Cellular Component	GO:0005634	nucleus	DDB1	IDA		Human	PMID:14751237
Cellular Component	GO:0005634	nucleus	DDB1	IDA		Human	PMID:18593899
Cellular Component	GO:0005634	nucleus	DDB1	IDA		Human	PMID:20223979
Cellular Component	GO:0032991	protein-containing complex	DDB1	IMP		Human	PMID:28437394
Biological Process	GO:0006915	apoptotic process	Ddb1	IMP	MGI:MGI:3698413	Mouse	PMID:24357321
Biological Process	GO:0051702	biological process involved in interaction with symbiont	DDB1	IDA		Human	PMID:23137809
Biological Process	GO:0034644	cellular response to UV	DDB1	EXP		Human	PMID:22118460
Biological Process	GO:0034644	cellular response to UV	Ddb1	EXP		Mouse	MGI:MGI:6867266|PMID:22118460
Biological Process	GO:0006974	DNA damage response	DDB1	IMP		Human	PMID:16949367
Biological Process	GO:0006974	DNA damage response	DDB1	EXP		Human	PMID:22118460
Biological Process	GO:0006974	DNA damage response	Ddb1	EXP		Mouse	MGI:MGI:6867266|PMID:22118460
Biological Process	GO:0035234	ectopic germ cell programmed cell death	Ddb1	IMP	MGI:MGI:3698413	Mouse	PMID:24357321
Biological Process	GO:0035518	histone H2A monoubiquitination	DDB1	IDA		Human	PMID:22334663
Biological Process	GO:0043066	negative regulation of apoptotic process	Ddb1	IMP	MGI:MGI:3698413	Mouse	PMID:24357321
Biological Process	GO:0043066	negative regulation of apoptotic process	ddb1	IMP	ZFIN:ZDB-GENO-151230-3	Zfish	PMID:26225764
Biological Process	GO:0051093	negative regulation of developmental process	Ddb1	IMP	MGI:MGI:3698413	Mouse	PMID:24357321
Biological Process	GO:2000242	negative regulation of reproductive process	Ddb1	IMP	MGI:MGI:3698413	Mouse	PMID:24357321
Biological Process	GO:0046726	positive regulation by virus of viral protein levels in host cell	DDB1	IMP		Human	PMID:23137809
Biological Process	GO:0045722	positive regulation of gluconeogenesis	Ddb1	IMP		Mouse	MGI:MGI:5914352|PMID:28790135
Biological Process	GO:0045732	positive regulation of protein catabolic process	DDB1	IDA		Human	PMID:14739464
Biological Process	GO:0045732	positive regulation of protein catabolic process	DDB1	IDA		Human	PMID:16949367
Biological Process	GO:0045732	positive regulation of protein catabolic process	DDB1	IMP		Human	PMID:16949367
Biological Process	GO:0045070	positive regulation of viral genome replication	DDB1	IMP		Human	PMID:23137809
Biological Process	GO:0010498	proteasomal protein catabolic process	DDB1	IMP		Human	PMID:25970626
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	DDB1	IMP		Human	PMID:14739464
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	DDB1	IMP		Human	PMID:20223979
Biological Process	GO:0016567	protein ubiquitination	DDB1	IDA		Human	PMID:26431207
Biological Process	GO:0016567	protein ubiquitination	DDB1	IMP		Human	PMID:28437394
Biological Process	GO:0016567	protein ubiquitination	DDB1	IDA		Human	PMID:28886238
Biological Process	GO:0016567	protein ubiquitination	Ddb1	IMP		Mouse	MGI:MGI:5908518|PMID:26431207
Biological Process	GO:0010564	regulation of cell cycle process	ddb1	IMP	ZFIN:ZDB-GENO-151230-3	Zfish	PMID:26225764
Biological Process	GO:0042752	regulation of circadian rhythm	Ddb1	IMP		Mouse	MGI:MGI:5908518|PMID:26431207
Biological Process	GO:1901990	regulation of mitotic cell cycle phase transition	DDB1	IMP		Human	PMID:17088560
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	DDB1	IDA		Human	PMID:11673459
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	DDB1	IMP		Human	PMID:26431207
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Ddb1	IMP		Mouse	MGI:MGI:5908518|PMID:26431207
Biological Process	GO:0070914	UV-damage excision repair	DDB1	IDA		Human	PMID:14751237
Biological Process	GO:0070914	UV-damage excision repair	DDB1	IDA		Human	PMID:22334663
Biological Process	GO:0019076	viral release from host cell	DDB1	IMP		Human	PMID:23137809
Biological Process	GO:0016055	Wnt signaling pathway	Ddb1	IDA		Mouse	PMID:19056892

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern