Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDR1
  • Mouse genes Ddr1
  • Rat genes Ddr1
  • Zfish genes ddr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	DDR1	IMP		Human	PMID:12065315
Molecular Function	GO:0005518	collagen binding	DDR1	IDA		Human	PMID:9659899
Molecular Function	GO:0005518	collagen binding	Ddr1	IMP		Mouse	MGI:MGI:3629583|PMID:12065315
Molecular Function	GO:0005518	collagen binding	Ddr1	IDA		Mouse	PMID:16806867
Molecular Function	GO:0005515	protein binding	DDR1	IPI	UniProtKB:O43639	Human	PMID:16337946
Molecular Function	GO:0005515	protein binding	DDR1	IPI	UniProtKB:Q06124	Human	PMID:16337946
Molecular Function	GO:0005515	protein binding	DDR1	IPI	UniProtKB:Q8IX03	Human	PMID:18190796
Molecular Function	GO:0005515	protein binding	DDR1	IPI	UniProtKB:Q16832	Human	PMID:35384245
Molecular Function	GO:0038062	protein tyrosine kinase collagen receptor activity	DDR1	IDA		Human	PMID:21044884
Molecular Function	GO:0038062	protein tyrosine kinase collagen receptor activity	DDR1	IDA		Human	PMID:9659899
Cellular Component	GO:0016323	basolateral plasma membrane	Ddr1	IDA		Rat	PMID:15218324|RGD:2303414
Cellular Component	GO:0005903	brush border	Ddr1	IDA		Rat	PMID:23195037|RGD:13508622
Cellular Component	GO:0005737	cytoplasm	Ddr1	IDA		Rat	PMID:23195037|RGD:13508622
Cellular Component	GO:0070062	extracellular exosome	DDR1	HDA		Human	PMID:19199708
Cellular Component	GO:0005615	extracellular space	DDR1	HDA		Human	PMID:16502470
Cellular Component	GO:0005886	plasma membrane	Ddr1	IDA		Mouse	PMID:12397034
Cellular Component	GO:0043235	receptor complex	DDR1	IDA		Human	PMID:23382219
Biological Process	GO:0031100	animal organ regeneration	Ddr1	IEP		Rat	PMID:15218324|RGD:2303414
Biological Process	GO:0061564	axon development	Ddr1	IMP		Mouse	PMID:10970885
Biological Process	GO:0060444	branching involved in mammary gland duct morphogenesis	Ddr1	IMP	MGI:MGI:2388024	Mouse	PMID:11283268
Biological Process	GO:0008283	cell population proliferation	Ddr1	IMP	MGI:MGI:2388024	Mouse	PMID:12397034
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	DDR1	IMP		Human	PMID:12065315
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	DDR1	IDA		Human	PMID:21044884
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	DDR1	IDA		Human	PMID:9659899
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Ddr1	IMP		Mouse	MGI:MGI:3629583|PMID:12065315
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Ddr1	IDA		Mouse	PMID:10970885
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Ddr1	IEP		Rat	PMID:28199848|RGD:151347403
Biological Process	GO:0043583	ear development	Ddr1	IMP	MGI:MGI:2388024	Mouse	PMID:11283268
Biological Process	GO:0007566	embryo implantation	Ddr1	IMP	MGI:MGI:2388024	Mouse	PMID:11283268
Biological Process	GO:0060749	mammary gland alveolus development	Ddr1	IMP	MGI:MGI:2388024	Mouse	PMID:11283268
Biological Process	GO:0008285	negative regulation of cell population proliferation	Ddr1	IMP	MGI:MGI:2388024	Mouse	PMID:12397034
Biological Process	GO:1990138	neuron projection extension	Ddr1	IMP		Mouse	PMID:10970885
Biological Process	GO:0038083	peptidyl-tyrosine autophosphorylation	DDR1	IDA		Human	PMID:21044884
Biological Process	GO:0038083	peptidyl-tyrosine autophosphorylation	Ddr1	IDA		Mouse	PMID:10970885
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Ddr1	IDA		Mouse	PMID:12397034
Biological Process	GO:0046777	protein autophosphorylation	DDR1	IDA		Human	PMID:9659899
Biological Process	GO:0046777	protein autophosphorylation	Ddr1	IDA		Mouse	PMID:10970885
Biological Process	GO:0001558	regulation of cell growth	Ddr1	IMP	MGI:MGI:2388024	Mouse	PMID:12397034
Biological Process	GO:0001952	regulation of cell-matrix adhesion	Ddr1	IMP	MGI:MGI:2388024	Mouse	PMID:12397034
Biological Process	GO:0010715	regulation of extracellular matrix disassembly	DDR1	IMP		Human	PMID:12065315
Biological Process	GO:0010715	regulation of extracellular matrix disassembly	Ddr1	IMP		Mouse	MGI:MGI:3629583|PMID:12065315
Biological Process	GO:0043588	skin development	Ddr1	IEP		Rat	PMID:11304604|RGD:2303415
Biological Process	GO:0014909	smooth muscle cell migration	DDR1	IMP		Human	PMID:12065315
Biological Process	GO:0014909	smooth muscle cell migration	Ddr1	IMP		Mouse	MGI:MGI:3629583|PMID:12065315
Biological Process	GO:0061302	smooth muscle cell-matrix adhesion	DDR1	IMP		Human	PMID:12065315
Biological Process	GO:0061302	smooth muscle cell-matrix adhesion	Ddr1	IMP		Mouse	MGI:MGI:3629583|PMID:12065315
Biological Process	GO:0042060	wound healing	Ddr1	IEP		Rat	PMID:28199848|RGD:151347403
Biological Process	GO:0044319	wound healing, spreading of cells	DDR1	IMP		Human	PMID:12065315
Biological Process	GO:0044319	wound healing, spreading of cells	Ddr1	IMP		Mouse	MGI:MGI:3629583|PMID:12065315

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern