Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0005518 | collagen binding | DDR2 | IDA | Human | PMID:20004161 | |
Molecular Function | GO:0005518 | collagen binding | Ddr2 | IDA | Mouse | PMID:16806867 | |
Molecular Function | GO:0005518 | collagen binding | Ddr2 | IDA | Rat | PMID:12220173|RGD:727757 | |
Molecular Function | GO:0005515 | protein binding | DDR2 | IPI | UniProtKB:P13942 | Human | PMID:17703188 |
Molecular Function | GO:0005515 | protein binding | DDR2 | IPI | UniProtKB:P08238 | Human | PMID:22939624 |
Molecular Function | GO:0005515 | protein binding | DDR2 | IPI | UniProtKB:Q16543 | Human | PMID:25036637 |
Molecular Function | GO:0005515 | protein binding | DDR2 | IPI | UniProtKB:P08238 | Human | PMID:35384245 |
Molecular Function | GO:0005515 | protein binding | DDR2 | IPI | UniProtKB:Q08345 | Human | PMID:35384245 |
Molecular Function | GO:0005515 | protein binding | DDR2 | IPI | UniProtKB:Q16288 | Human | PMID:35384245 |
Molecular Function | GO:0005515 | protein binding | DDR2 | IPI | UniProtKB:Q16543 | Human | PMID:35384245 |
Molecular Function | GO:0038062 | protein tyrosine kinase collagen receptor activity | DDR2 | IDA | Human | PMID:9659899 | |
Molecular Function | GO:0038062 | protein tyrosine kinase collagen receptor activity | Ddr2 | IDA | Mouse | MGI:MGI:2158097|PMID:11723120 | |
Molecular Function | GO:0004714 | transmembrane receptor protein tyrosine kinase activity | DDR2 | IDA | Human | PMID:20004161 | |
Cellular Component | GO:0015629 | actin cytoskeleton | DDR2 | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0016324 | apical plasma membrane | Ddr2 | IDA | Rat | PMID:15218324|RGD:2303414 | |
Cellular Component | GO:0005925 | focal adhesion | DDR2 | HDA | Human | PMID:21423176 | |
Cellular Component | GO:0005886 | plasma membrane | DDR2 | IDA | Human | GO_REF:0000052 | |
Biological Process | GO:0031214 | biomineral tissue development | Ddr2 | IMP | Mouse | MGI:MGI:5318020|PMID:19900459 | |
Biological Process | GO:1904385 | cellular response to angiotensin | Ddr2 | IEP | Rat | PMID:26674152|RGD:11554781 | |
Biological Process | GO:0071456 | cellular response to hypoxia | Ddr2 | IEP | Rat | PMID:18664364|RGD:150429768 | |
Biological Process | GO:0071560 | cellular response to transforming growth factor beta stimulus | Ddr2 | IEP | Rat | PMID:16087782|RGD:150429767 | |
Biological Process | GO:0035988 | chondrocyte proliferation | Ddr2 | IMP | Mouse | MGI:MGI:2158837|PMID:11375938 | |
Biological Process | GO:0030199 | collagen fibril organization | Ddr2 | IMP | Mouse | MGI:MGI:5318020|PMID:19900459 | |
Biological Process | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway | DDR2 | IDA | Human | PMID:16186108 | |
Biological Process | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway | Ddr2 | IDA | Mouse | MGI:MGI:2158097|PMID:11723120 | |
Biological Process | GO:0003416 | endochondral bone growth | Ddr2 | IMP | Mouse | MGI:MGI:2158837|PMID:11375938 | |
Biological Process | GO:0043066 | negative regulation of apoptotic process | Ddr2 | IMP | Rat | PMID:23409069|RGD:150517731 | |
Biological Process | GO:1901299 | negative regulation of hydrogen peroxide-mediated programmed cell death | Ddr2 | IMP | Rat | PMID:32412792|RGD:150429761 | |
Biological Process | GO:0033673 | negative regulation of kinase activity | Ddr2 | IMP | Rat | PMID:19762078|RGD:150429972 | |
Biological Process | GO:0060547 | negative regulation of necrotic cell death | Ddr2 | IMP | Rat | PMID:23409069|RGD:150517731 | |
Biological Process | GO:0018108 | peptidyl-tyrosine phosphorylation | DDR2 | IDA | Human | PMID:20004161 | |
Biological Process | GO:0008284 | positive regulation of cell population proliferation | Ddr2 | IMP | MGI:MGI:2388155 | Mouse | PMID:11723120 |
Biological Process | GO:0032967 | positive regulation of collagen biosynthetic process | Ddr2 | IDA | Rat | PMID:24938620|RGD:150429973 | |
Biological Process | GO:0032967 | positive regulation of collagen biosynthetic process | Ddr2 | IMP | Rat | PMID:26674152|RGD:11554781 | |
Biological Process | GO:0051091 | positive regulation of DNA-binding transcription factor activity | DDR2 | IMP | Human | PMID:20564243 | |
Biological Process | GO:0070374 | positive regulation of ERK1 and ERK2 cascade | Ddr2 | IMP | Rat | PMID:26674152|RGD:11554781 | |
Biological Process | GO:0090091 | positive regulation of extracellular matrix disassembly | Ddr2 | IMP | Mouse | MGI:MGI:2158097|PMID:11723120 | |
Biological Process | GO:0010763 | positive regulation of fibroblast migration | Ddr2 | IMP | Mouse | MGI:MGI:2158097|PMID:11723120 | |
Biological Process | GO:0048146 | positive regulation of fibroblast proliferation | Ddr2 | IMP | Mouse | MGI:MGI:2158097|PMID:11723120 | |
Biological Process | GO:0048146 | positive regulation of fibroblast proliferation | Ddr2 | IMP | Mouse | MGI:MGI:2158837|PMID:11375938 | |
Biological Process | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle | Ddr2 | IMP | Rat | PMID:32412792|RGD:150429761 | |
Biological Process | GO:2000491 | positive regulation of hepatic stellate cell activation | Ddr2 | IMP | Rat | PMID:23409069|RGD:150517731 | |
Biological Process | GO:1904899 | positive regulation of hepatic stellate cell proliferation | Ddr2 | IMP | Rat | PMID:23409069|RGD:150517731 | |
Biological Process | GO:1901216 | positive regulation of neuron death | Ddr2 | IMP | Rat | PMID:28863860|RGD:150519888 | |
Biological Process | GO:0045669 | positive regulation of osteoblast differentiation | DDR2 | IMP | Human | PMID:20564243 | |
Biological Process | GO:0045860 | positive regulation of protein kinase activity | DDR2 | IMP | Human | PMID:20564243 | |
Biological Process | GO:1904754 | positive regulation of vascular associated smooth muscle cell migration | Ddr2 | IMP | Rat | PMID:18664364|RGD:150429768 | |
Biological Process | GO:1904707 | positive regulation of vascular associated smooth muscle cell proliferation | Ddr2 | IMP | Rat | PMID:16087782|RGD:150429767 | |
Biological Process | GO:0090303 | positive regulation of wound healing | Ddr2 | IMP | Rat | PMID:26674152|RGD:11554781 | |
Biological Process | GO:0046777 | protein autophosphorylation | DDR2 | IDA | Human | PMID:16186108 | |
Biological Process | GO:0046777 | protein autophosphorylation | Ddr2 | IDA | Mouse | PMID:16806867 | |
Biological Process | GO:0030500 | regulation of bone mineralization | DDR2 | IMP | Human | PMID:20564243 | |
Biological Process | GO:0034103 | regulation of tissue remodeling | DDR2 | IMP | Human | PMID:30449416 | |
Biological Process | GO:0035994 | response to muscle stretch | Ddr2 | IEP | Rat | PMID:16087782|RGD:150429767 | |
Biological Process | GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | Ddr2 | IDA | Mouse | PMID:11723120 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/27/2024 MGI 6.24 |
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