Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDX4
  • Mouse genes Ddx4
  • Rat genes Ddx4
  • Zfish genes ddx4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddx4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	Ddx4	IMP		Mouse	MGI:MGI:5908740|PMID:28633017
Molecular Function	GO:0140693	molecular condensate scaffold activity	DDX4	EXP		Human	PMID:25747659
Molecular Function	GO:0005515	protein binding	Ddx4	IPI	UniProtKB:O08785|UniProtKB:Q9WTL8	Mouse	MGI:MGI:5447260|PMID:22900038
Molecular Function	GO:0005515	protein binding	Ddx4	IPI	UniProtKB:Q99MV2|UniProtKB:Q9D5S1	Mouse	MGI:MGI:5908497|PMID:28254886
Molecular Function	GO:0005515	protein binding	Ddx4	IPI	UniProtKB:P61407	Mouse	MGI:MGI:3847167|PMID:19345099
Molecular Function	GO:0005515	protein binding	Ddx4	IPI	UniProtKB:Q9UPY3-1	Mouse	MGI:MGI:3620612|PMID:16477042
Molecular Function	GO:0005515	protein binding	Ddx4	IPI	UniProtKB:Q8VD46	Mouse	MGI:MGI:4356194|PMID:19730684
Molecular Function	GO:0005515	protein binding	Ddx4	IPI	UniProtKB:Q8BVN9	Mouse	MGI:MGI:3655410|PMID:16787967
Molecular Function	GO:0005515	protein binding	Ddx4	IPI	PR:P69566	Mouse	PMID:14648869
Molecular Function	GO:0005515	protein binding	Ddx4	IPI	PR:Q8K1H1	Mouse	PMID:17141210
Cellular Component	GO:0033391	chromatoid body	Ddx4	IDA		Mouse	PMID:10781947
Cellular Component	GO:0033391	chromatoid body	Ddx4	IDA		Mouse	PMID:22792342
Cellular Component	GO:0033391	chromatoid body	Ddx4	IDA		Rat	PMID:24141902|RGD:10755411
Cellular Component	GO:0005737	cytoplasm	DDX4	IDA		Human	PMID:21421998
Cellular Component	GO:0005737	cytoplasm	Ddx4	IDA		Mouse	PMID:15749075
Cellular Component	GO:0005737	cytoplasm	Ddx4	IDA		Mouse	PMID:10781947
Cellular Component	GO:0005737	cytoplasm	Ddx4	IDA		Mouse	PMID:12798292
Cellular Component	GO:0005737	cytoplasm	Ddx4	IDA		Mouse	PMID:14736746
Cellular Component	GO:0005737	cytoplasm	Ddx4	IDA		Mouse	PMID:15789443
Cellular Component	GO:0005634	nucleus	Ddx4	IDA		Mouse	PMID:12798292
Cellular Component	GO:0043186	P granule	ddx4	IDA		Zfish	PMID:11691838
Cellular Component	GO:0043186	P granule	ddx4	IDA		Zfish	PMID:18507824
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ddx4	IDA		Mouse	PMID:10781947
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ddx4	IDA		Mouse	PMID:21991325
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ddx4	IDA		Rat	PMID:24141902|RGD:10755411
Cellular Component	GO:0071546	pi-body	Ddx4	IDA		Mouse	MGI:MGI:4443217|PMID:20439430
Cellular Component	GO:0071546	pi-body	Ddx4	IDA		Mouse	MGI:MGI:4417983|PMID:20011505
Cellular Component	GO:0071546	pi-body	Ddx4	IDA		Mouse	PMID:22792342
Cellular Component	GO:0071547	piP-body	Ddx4	IDA		Mouse	MGI:MGI:4417983|PMID:20011505
Cellular Component	GO:1990904	ribonucleoprotein complex	Ddx4	IDA		Mouse	PMID:17141210
Biological Process	GO:0043046	DNA methylation involved in gamete generation	Ddx4	IMP		Mouse	MGI:MGI:4443217|PMID:20439430
Biological Process	GO:0030317	flagellated sperm motility	DDX4	IMP		Human	PMID:21034600
Biological Process	GO:0007281	germ cell development	ddx4	IMP	ZFIN:ZDB-GENO-180315-5	Zfish	PMID:25257909
Biological Process	GO:0008406	gonad development	ddx4	IEP		Zfish	PMID:15196960
Biological Process	GO:0007141	male meiosis I	Ddx4	IMP		Mouse	MGI:MGI:5908740|PMID:28633017
Biological Process	GO:0007141	male meiosis I	Ddx4	IMP	MGI:MGI:2182568	Mouse	PMID:10766740
Biological Process	GO:0007140	male meiotic nuclear division	Ddx4	IMP		Mouse	MGI:MGI:4443217|PMID:20439430
Biological Process	GO:0010529	negative regulation of transposition	Ddx4	IMP		Mouse	MGI:MGI:5908740|PMID:28633017
Biological Process	GO:0034587	piRNA processing	Ddx4	IMP		Mouse	MGI:MGI:5908740|PMID:28633017
Biological Process	GO:0034587	piRNA processing	Ddx4	IMP		Mouse	MGI:MGI:4443217|PMID:20439430
Biological Process	GO:0051445	regulation of meiotic cell cycle	ddx4	IMP	ZFIN:ZDB-GENO-180315-5	Zfish	PMID:25257909
Biological Process	GO:0032880	regulation of protein localization	Ddx4	IMP	MGI:MGI:2182568	Mouse	PMID:17141210
Biological Process	GO:0080021	response to benzoic acid	Ddx4	IEP		Rat	PMID:30476341|RGD:151893502
Biological Process	GO:0032526	response to retinoic acid	Ddx4	HEP		Rat	PMID:30329139|RGD:151893506
Biological Process	GO:0032526	response to retinoic acid	Ddx4	IEP		Rat	PMID:30476341|RGD:151893502
Biological Process	GO:0007283	spermatogenesis	Ddx4	IMP		Mouse	MGI:MGI:4443217|PMID:20439430
Biological Process	GO:0007283	spermatogenesis	Ddx4	IMP		Mouse	MGI:MGI:5908740|PMID:28633017
Biological Process	GO:0007283	spermatogenesis	Ddx4	IMP	MGI:MGI:2182568	Mouse	PMID:10766740
Biological Process	GO:0007283	spermatogenesis	Ddx4	IEP		Rat	PMID:24141902|RGD:10755411

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern