Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDX41
  • Mouse genes Ddx41
  • Rat genes Ddx41
  • Zfish genes ddx41
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddx41

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Ddx41	IDA		Mouse	PMID:21892174
Molecular Function	GO:0005515	protein binding	DDX41	IPI	UniProtKB:Q8N5F7	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	DDX41	IPI	UniProtKB:Q8IUQ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DDX41	IPI	UniProtKB:Q8NHQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DDX41	IPI	UniProtKB:Q03468	Human	PMID:26030138
Molecular Function	GO:0005515	protein binding	DDX41	IPI	UniProtKB:Q8N5F7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DDX41	IPI	UniProtKB:Q5M9Q1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DDX41	IPI	UniProtKB:Q96BJ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DDX41	IPI	UniProtKB:Q14320	Human	PMID:32703943
Molecular Function	GO:0005515	protein binding	DDX41	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ddx41	IPI	UniProtKB:Q62191	Mouse	MGI:MGI:5465368|PMID:23222971
Molecular Function	GO:0005515	protein binding	Ddx41	IPI	UniProtKB:Q3TBT3	Mouse	MGI:MGI:5508701|PMID:23142775
Molecular Function	GO:0005515	protein binding	Ddx41	IPI	PR:Q3TBT3	Mouse	PMID:21892174
Molecular Function	GO:0003723	RNA binding	DDX41	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	DDX41	HDA		Human	PMID:22681889
Cellular Component	GO:0071013	catalytic step 2 spliceosome	DDX41	IDA		Human	PMID:11991638
Cellular Component	GO:0005737	cytoplasm	ddx41	IMP		Zfish	PMID:29942316
Cellular Component	GO:0005783	endoplasmic reticulum	Ddx41	IDA		Mouse	PMID:21892174
Cellular Component	GO:0016020	membrane	DDX41	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	DDX41	IDA		Human	PMID:26712909
Cellular Component	GO:0005634	nucleus	Ddx41	IDA		Mouse	PMID:21892174
Cellular Component	GO:0005634	nucleus	ddx41	IMP		Zfish	PMID:29942316
Biological Process	GO:0030154	cell differentiation	DDX41	IMP		Human	PMID:25920683
Biological Process	GO:0008283	cell population proliferation	DDX41	IMP		Human	PMID:25920683
Biological Process	GO:0035458	cellular response to interferon-beta	Ddx41	IMP		Mouse	PMID:21892174
Biological Process	GO:0051607	defense response to virus	Ddx41	IMP		Mouse	PMID:21892174
Biological Process	GO:0045087	innate immune response	ddx41	IMP	ZFIN:ZDB-MRPHLNO-171109-3	Zfish	PMID:29942316
Biological Process	GO:0000398	mRNA splicing, via spliceosome	DDX41	IMP		Human	PMID:25920683
Biological Process	GO:0038061	NIK/NF-kappaB signaling	ddx41	IGI	ZFIN:ZDB-GENE-120921-1	Zfish	PMID:29942316
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ddx41	IDA		Mouse	PMID:21892174
Biological Process	GO:0009615	response to virus	ddx41	IMP	ZFIN:ZDB-MRPHLNO-171109-3	Zfish	PMID:25972544
Biological Process	GO:0009615	response to virus	ddx41	IGI	ZFIN:ZDB-GENE-070912-171	Zfish	PMID:25972544

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern