Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDX46
  • Mouse genes Ddx46
  • Rat genes Ddx46
  • Zfish genes ddx46
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddx46

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DDX46	IPI	UniProtKB:P78362	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	DDX46	IPI	UniProtKB:P78362	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	DDX46	IPI	UniProtKB:P78362	Human	PMID:32707033
Molecular Function	GO:0003723	RNA binding	DDX46	HDA		Human	PMID:22681889
Cellular Component	GO:0001650	fibrillar center	DDX46	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	DDX46	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DDX46	HDA		Human	PMID:16791210
Cellular Component	GO:0005634	nucleus	Ddx46	IDA		Rat	PMID:7797571|RGD:1299470
Biological Process	GO:0007420	brain development	ddx46	IMP	ZFIN:ZDB-GENO-120404-4	Zfish	PMID:22442707
Biological Process	GO:0060216	definitive hemopoiesis	ddx46	IMP	ZFIN:ZDB-GENO-160513-3	Zfish	PMID:23635340
Biological Process	GO:0048546	digestive tract morphogenesis	ddx46	IMP	ZFIN:ZDB-GENO-120404-4	Zfish	PMID:22442707
Biological Process	GO:0048546	digestive tract morphogenesis	ddx46	IMP	ZFIN:ZDB-GENO-120330-2	Zfish	PMID:22442707
Biological Process	GO:0031017	exocrine pancreas development	ddx46	IMP	ZFIN:ZDB-GENO-120330-2	Zfish	PMID:22442707
Biological Process	GO:0031017	exocrine pancreas development	ddx46	IMP	ZFIN:ZDB-GENO-120404-5	Zfish	PMID:22442707
Biological Process	GO:0031017	exocrine pancreas development	ddx46	IMP	ZFIN:ZDB-GENO-120404-4	Zfish	PMID:22442707
Biological Process	GO:0072576	liver morphogenesis	ddx46	IMP	ZFIN:ZDB-GENO-120404-4	Zfish	PMID:22442707
Biological Process	GO:0072576	liver morphogenesis	ddx46	IMP	ZFIN:ZDB-GENO-120330-2	Zfish	PMID:22442707
Biological Process	GO:0000398	mRNA splicing, via spliceosome	ddx46	IMP	ZFIN:ZDB-GENO-160513-3	Zfish	PMID:23635340
Biological Process	GO:0000398	mRNA splicing, via spliceosome	ddx46	IMP	ZFIN:ZDB-GENO-120330-2	Zfish	PMID:22442707
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	ddx46	IMP	ZFIN:ZDB-GENO-160513-3	Zfish	PMID:23635340
Biological Process	GO:1902038	positive regulation of hematopoietic stem cell differentiation	ddx46	IMP	ZFIN:ZDB-GENO-160513-3	Zfish	PMID:23635340
Biological Process	GO:0045621	positive regulation of lymphocyte differentiation	ddx46	IMP	ZFIN:ZDB-GENO-160513-3	Zfish	PMID:23635340

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern