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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ddx6

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddx6
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0045296cadherin bindingDDX6HDAHumanPMID:25468996
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96F86HumanPMID:16364915
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NPI6HumanPMID:16364915
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9HC16HumanPMID:16699599
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9UKV8HumanPMID:16756390
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q99700HumanPMID:17392519
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NPI6HumanPMID:19966221
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q86TB9HumanPMID:20543818
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q86TB9HumanPMID:20584987
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:A6NIX2HumanPMID:20616046
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96IF1HumanPMID:20616046
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9UGP4HumanPMID:20616046
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8NF91HumanPMID:24862572
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96F86HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q99700HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NPI6HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NPI6HumanPMID:25036637
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:O94972HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P14373HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P15884HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P17028HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P60410HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q08117HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q08379HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q13137HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q13422HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q15233-2HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q59EK9HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q6A162HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8N1B4HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8N7W2-2HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8NHQ1HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96BR9HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96C92-2HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96CA5HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96F86HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96PV4HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NRA8HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:C9JLW8HumanPMID:26184334
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q7Z417HumanPMID:26184334
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9BUT9HumanPMID:26184334
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P10636-8HumanPMID:26269332
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NPI6HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9P2F8-2HumanPMID:27107012
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NRA8HumanPMID:27342281
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96F86HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NPI6HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9UKV8HumanPMID:28683311
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8ND56HumanPMID:29510985
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96F86HumanPMID:29892012
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P10636-8HumanPMID:29966762
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q5JR59-3HumanPMID:30886144
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q6P2E9HumanPMID:31422817
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q86TB9HumanPMID:31422817
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8ND56HumanPMID:31422817
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96F86HumanPMID:31422817
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9BX40HumanPMID:31422817
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NRA8HumanPMID:31422817
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:O75420HumanPMID:31439631
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q6Y7W6HumanPMID:31439631
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q86TB9HumanPMID:31439631
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8ND56HumanPMID:31439631
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96F86HumanPMID:31439631
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NRA8HumanPMID:31439631
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96CA5HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96F86HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:A0A0C3SFZ9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:O43298HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:O43829HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:O60504HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:O75420HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:O76011HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P14373HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P14923HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P15884-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P17661HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P34896HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P41219HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P51114-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P57052HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P60410HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P78424HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q04864-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q05BL1HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q08117-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q08379HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q12933HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q13123HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q13137HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q13422-7HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q14696HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q15742HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q495M9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q49A88-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q53FD0-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q5JR59-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q5JST6HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q6P9H4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q6PI77HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q86X45HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8N1B4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8ND83HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8NHQ1HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q8TAP6HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q92841HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96BR9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96CA5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96DT7-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96ED9-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96EL1HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96F86HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96KG9-4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q96N16HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q99081-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9BUH8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9BYV2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NR12HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NRA8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NRD5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NRI5-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9NWH7-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9P286HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9P2F8-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9UGI0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9Y250HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:Q9Y5V3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingDDX6IPIUniProtKB:P0DTC9HumanPMID:35107372
Molecular FunctionGO:0019904protein domain specific bindingDDX6IPIUniProtKB:A5YKK6HumanPMID:24768540
Molecular FunctionGO:0003723RNA bindingDDX6HDAHumanPMID:22658674
Molecular FunctionGO:0003723RNA bindingDDX6HDAHumanPMID:22681889
Cellular ComponentGO:0005912adherens junctionDdx6IDARatPMID:24141902|RGD:10755411
Cellular ComponentGO:0033391chromatoid bodyDdx6IDARatPMID:24141902|RGD:10755411
Cellular ComponentGO:0061830concave side of sperm headDdx6IDARatPMID:24141902|RGD:10755411
Cellular ComponentGO:0005737cytoplasmDDX6IDAHumanPMID:26184334
Cellular ComponentGO:0005737cytoplasmDDX6IDAHumanPMID:28216671
Cellular ComponentGO:0005737cytoplasmDdx6IDAMousePMID:20014101
Cellular ComponentGO:0036464cytoplasmic ribonucleoprotein granuleDDX6IDAHumanGO_REF:0000052
Cellular ComponentGO:0036464cytoplasmic ribonucleoprotein granuleddx61IDAZfishPMID:27489304
Cellular ComponentGO:0036464cytoplasmic ribonucleoprotein granuleddx6IDAZfishPMID:27489304
Cellular ComponentGO:0010494cytoplasmic stress granuleDDX6IDAHumanPMID:17392519
Cellular ComponentGO:0010494cytoplasmic stress granuleDDX6IDAHumanPMID:26184334
Cellular ComponentGO:0005829cytosolDDX6IDAHumanGO_REF:0000052
Cellular ComponentGO:0000792heterochromatinDdx6IDARatPMID:24141902|RGD:10755411
Cellular ComponentGO:0016020membraneDDX6HDAHumanPMID:19946888
Cellular ComponentGO:0005739mitochondrionDdx6IDARatPMID:24141902|RGD:10755411
Cellular ComponentGO:0005730nucleolusDdx6IDARatPMID:24141902|RGD:10755411
Cellular ComponentGO:0005634nucleusDDX6IDAHumanPMID:26184334
Cellular ComponentGO:0005634nucleusDDX6IDAHumanPMID:28216671
Cellular ComponentGO:0001520outer dense fiberDdx6IDARatPMID:24141902|RGD:10755411
Cellular ComponentGO:0000932P-bodyDDX6IDAHumanPMID:16699599
Cellular ComponentGO:0000932P-bodyDDX6IDAHumanPMID:20616046
Cellular ComponentGO:0000932P-bodyDDX6IDAHumanPMID:20826699
Cellular ComponentGO:0000932P-bodyDDX6IDAHumanPMID:22915799
Cellular ComponentGO:0000932P-bodyDDX6IDAHumanPMID:23125361
Cellular ComponentGO:0000932P-bodyDDX6IDAHumanPMID:25995375
Cellular ComponentGO:0000932P-bodyDDX6IDAHumanPMID:31422817
Cellular ComponentGO:0000932P-bodyDDX6IMPHumanPMID:22022269
Cellular ComponentGO:0000932P-bodyDdx6IDAMousePMID:25456498
Cellular ComponentGO:0048471perinuclear region of cytoplasmDdx6IDARatPMID:24141902|RGD:10755411
Cellular ComponentGO:0016442RISC complexDDX6IDAHumanPMID:20616046
Cellular ComponentGO:0097227sperm annulusDdx6IDARatPMID:24141902|RGD:10755411
Biological ProcessGO:0035278miRNA-mediated gene silencing by inhibition of translationDDX6IDAHumanPMID:27342281
Biological ProcessGO:0045665negative regulation of neuron differentiationDdx6IMPMousePMID:25456498
Biological ProcessGO:0017148negative regulation of translationDDX6IDAHumanPMID:27342281
Biological ProcessGO:0030182neuron differentiationDdx6IMPMousePMID:25456498
Biological ProcessGO:0033962P-body assemblyDDX6IDAHumanPMID:20826699
Biological ProcessGO:0033962P-body assemblyDDX6IMPHumanPMID:25995375
Biological ProcessGO:0033962P-body assemblyDDX6IDAHumanPMID:27342281
Biological ProcessGO:0033962P-body assemblyDDX6IMPHumanPMID:31422817
Biological ProcessGO:0009408response to heatddx61IGIZFIN:ZDB-MRPHLNO-161208-1,ZFIN:ZDB-MRPHLNO-161208-2ZfishPMID:27489304
Biological ProcessGO:0009408response to heatddx6IGIZFIN:ZDB-MRPHLNO-161208-1,ZFIN:ZDB-MRPHLNO-161208-2ZfishPMID:27489304
Biological ProcessGO:0048515spermatid differentiationDdx6IEPRatPMID:24141902|RGD:10755411
Biological ProcessGO:0007283spermatogenesisDdx6IEPRatPMID:24141902|RGD:10755411
Biological ProcessGO:0019827stem cell population maintenanceDdx6IMPMousePMID:25456498
Biological ProcessGO:0034063stress granule assemblyddx61IMPZFIN:ZDB-MRPHLNO-161208-2ZfishPMID:27489304
Biological ProcessGO:0034063stress granule assemblyddx61IGIZFIN:ZDB-MRPHLNO-161208-1,ZFIN:ZDB-MRPHLNO-161208-2ZfishPMID:27489304
Biological ProcessGO:0034063stress granule assemblyddx6IMPZFIN:ZDB-MRPHLNO-161208-1ZfishPMID:27489304
Biological ProcessGO:0034063stress granule assemblyddx6IGIZFIN:ZDB-MRPHLNO-161208-1,ZFIN:ZDB-MRPHLNO-161208-2ZfishPMID:27489304
Biological ProcessGO:0019074viral RNA genome packagingDDX6IMPHumanPMID:22022269

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory