Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DEAF1
  • Mouse genes Deaf1
  • Rat genes Deaf1
  • Zfish genes deaf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Deaf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	DEAF1	IDA		Human	PMID:24726472
Molecular Function	GO:0005515	protein binding	DEAF1	IPI	UniProtKB:P49840	Human	PMID:20368287
Molecular Function	GO:0005515	protein binding	DEAF1	IPI	UniProtKB:P49841	Human	PMID:20368287
Molecular Function	GO:0005515	protein binding	DEAF1	IPI	UniProtKB:P42771	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	DEAF1	IPI	UniProtKB:P12956	Human	PMID:22442688
Molecular Function	GO:0005515	protein binding	DEAF1	IPI	UniProtKB:P51608	Human	PMID:29636529
Molecular Function	GO:0005515	protein binding	DEAF1	IPI	UniProtKB:P49840	Human	PMID:30824926
Molecular Function	GO:0005515	protein binding	DEAF1	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEAF1	IPI	UniProtKB:Q8TAP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEAF1	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DEAF1	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Deaf1	IPI	UniProtKB:Q9Z2D6	Mouse	MGI:MGI:6163374|PMID:29636529
Molecular Function	GO:0005515	protein binding	Deaf1	IPI	PR:P25801	Mouse	PMID:9860983
Molecular Function	GO:0005515	protein binding	Deaf1	IPI	PR:P61969	Mouse	PMID:9860983
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	DEAF1	IDA		Human	PMID:24726472
Cellular Component	GO:0005737	cytoplasm	Deaf1	IDA		Mouse	MGI:MGI:4355246|PMID:19668219
Cellular Component	GO:0001650	fibrillar center	DEAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DEAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Deaf1	IDA		Mouse	MGI:MGI:4355246|PMID:19668219
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	Deaf1	IDA		Mouse	PMID:9860983
Biological Process	GO:0001662	behavioral fear response	Deaf1	IMP		Mouse	MGI:MGI:5576037|PMID:24726472
Biological Process	GO:0048706	embryonic skeletal system development	Deaf1	IMP		Mouse	MGI:MGI:3029622|PMID:14966286
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	DEAF1	IDA		Human	PMID:24726472
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	DEAF1	IDA		Human	PMID:24726472
Biological Process	GO:0001843	neural tube closure	Deaf1	IMP		Mouse	MGI:MGI:3029622|PMID:14966286
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	DEAF1	IDA		Human	PMID:24726472
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Deaf1	IDA		Rat	PMID:9773984|RGD:728204
Biological Process	GO:0033599	regulation of mammary gland epithelial cell proliferation	DEAF1	IDA		Human	PMID:18826651
Biological Process	GO:0033599	regulation of mammary gland epithelial cell proliferation	Deaf1	IMP		Mouse	MGI:MGI:3822223|PMID:18826651
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Deaf1	IDA		Mouse	PMID:9860983
Biological Process	GO:0008542	visual learning	Deaf1	IMP		Mouse	MGI:MGI:5576037|PMID:24726472

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern