Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DEFB106A,DEFB106B
  • Mouse genes Defb34
  • Rat genes Defb15
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Defb34

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031727	CCR2 chemokine receptor binding	DEFB106A	IDA		Human	PMID:23938203
Molecular Function	GO:0008201	heparin binding	DEFB106A	IDA		Human	PMID:24189797
Molecular Function	GO:0001530	lipopolysaccharide binding	DEFB106A	IDA		Human	PMID:24189797
Molecular Function	GO:0005515	protein binding	DEFB106A	IPI	UniProtKB:P41597	Human	PMID:23938203
Cellular Component	GO:0019898	extrinsic component of membrane	DEFB106A	IDA		Human	PMID:23938203
Cellular Component	GO:1990742	microvesicle	DEFB106A	IDA		Human	PMID:23938203
Cellular Component	GO:0005634	nucleus	DEFB106A	IDA		Human	PMID:24189797
Biological Process	GO:0061760	antifungal innate immune response	DEFB106A	IDA		Human	PMID:24189797
Biological Process	GO:0050829	defense response to Gram-negative bacterium	DEFB106A	IDA		Human	PMID:24189797
Biological Process	GO:0050830	defense response to Gram-positive bacterium	DEFB106A	IDA		Human	PMID:24189797
Biological Process	GO:0045087	innate immune response	DEFB106A	IDA		Human	PMID:24189797

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern