Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DEGS1
  • Mouse genes Degs1
  • Rat genes Degs1
  • Zfish genes degs1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Degs1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DEGS1	IPI	UniProtKB:Q8WVX3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEGS1	IPI	UniProtKB:Q9NTN9-2	Human	PMID:32296183
Molecular Function	GO:0050251	retinol isomerase activity	DEGS1	IDA		Human	PMID:23143414
Molecular Function	GO:0050251	retinol isomerase activity	Degs1	IDA		Mouse	MGI:MGI:6414703|PMID:23143414
Molecular Function	GO:0042284	sphingolipid delta-4 desaturase activity	DEGS1	IMP		Human	PMID:30620337
Molecular Function	GO:0042284	sphingolipid delta-4 desaturase activity	DEGS1	IMP		Human	PMID:30620338
Molecular Function	GO:0042284	sphingolipid delta-4 desaturase activity	Degs1	IMP	MGI:MGI:3529540	Mouse	PMID:22984457
Cellular Component	GO:0005739	mitochondrion	DEGS1	IDA		Human	GO_REF:0000052
Biological Process	GO:0046513	ceramide biosynthetic process	Degs1	IMP	MGI:MGI:3529540	Mouse	PMID:22984457
Biological Process	GO:0043217	myelin maintenance	DEGS1	IMP		Human	PMID:30620337
Biological Process	GO:0043217	myelin maintenance	DEGS1	IMP		Human	PMID:30620338
Biological Process	GO:0043065	positive regulation of apoptotic process	Degs1	IMP	MGI:MGI:3529540	Mouse	PMID:22984457

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern