Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DENND1A
  • Mouse genes Dennd1a
  • Rat genes Dennd1a
  • Zfish genes dennd1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dennd1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	DENND1A	IDA		Human	PMID:20937701
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Dennd1a	IDA		Mouse	MGI:MGI:5751677|PMID:20159556
Molecular Function	GO:1901981	phosphatidylinositol phosphate binding	Dennd1a	IDA		Mouse	MGI:MGI:5751677|PMID:20159556
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	Dennd1a	IDA		Mouse	MGI:MGI:5751677|PMID:20159556
Molecular Function	GO:0005515	protein binding	Dennd1a	IPI	PR:P17427	Mouse	PMID:17182770
Molecular Function	GO:0017124	SH3 domain binding	Dennd1a	IPI	PR:Q9Z0R4	Mouse	PMID:17182770
Molecular Function	GO:0017124	SH3 domain binding	Dennd1a	IPI	PR:Q62420	Mouse	PMID:17182770
Molecular Function	GO:0031267	small GTPase binding	Dennd1a	IPI	UniProtKB:Q6PHN9	Mouse	MGI:MGI:5751677|PMID:20159556
Cellular Component	GO:0030136	clathrin-coated vesicle	DENND1A	IDA		Human	PMID:20937701
Cellular Component	GO:0030136	clathrin-coated vesicle	Dennd1a	IDA		Mouse	PMID:17182770
Cellular Component	GO:0030665	clathrin-coated vesicle membrane	Dennd1a	IDA		Mouse	MGI:MGI:5751677|PMID:20159556
Cellular Component	GO:0030665	clathrin-coated vesicle membrane	Dennd1a	IDA		Mouse	PMID:17182770
Cellular Component	GO:0005829	cytosol	DENND1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030425	dendrite	Dennd1a	IDA		Mouse	PMID:17182770
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	DENND1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043025	neuronal cell body	Dennd1a	IDA		Mouse	PMID:17182770
Cellular Component	GO:0045202	synapse	Dennd1a	IDA		Mouse	PMID:17182770
Biological Process	GO:0032456	endocytic recycling	Dennd1a	IDA		Mouse	MGI:MGI:5751677|PMID:20159556
Biological Process	GO:0006897	endocytosis	DENND1A	IMP		Human	PMID:20937701
Biological Process	GO:0043547	positive regulation of GTPase activity	Dennd1a	IDA		Mouse	MGI:MGI:5751677|PMID:20159556
Biological Process	GO:0032483	regulation of Rab protein signal transduction	DENND1A	IDA		Human	PMID:20937701
Biological Process	GO:0048488	synaptic vesicle endocytosis	Dennd1a	IDA		Mouse	PMID:17182770

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern