Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DERL1
  • Mouse genes Derl1
  • Rat genes Derl1
  • Zfish genes derl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Derl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	DERL1	IPI	UniProtKB:P55072	Human	PMID:16186510
Molecular Function	GO:0051117	ATPase binding	DERL1	IPI	UniProtKB:P55072	Human	PMID:24089527
Molecular Function	GO:0051117	ATPase binding	DERL1	IPI	UniProtKB:P55072	Human	PMID:27714797
Molecular Function	GO:0042802	identical protein binding	DERL1	IPI	UniProtKB:Q9BUN8	Human	PMID:16186510
Molecular Function	GO:0042288	MHC class I protein binding	DERL1	IDA		Human	PMID:15215855
Molecular Function	GO:0002020	protease binding	DERL1	IPI	UniProtKB:Q8TCT9	Human	PMID:25239945
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:P09727	Human	PMID:15215856
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:P55072	Human	PMID:15215856
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q9BQE4	Human	PMID:15215856
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:P13569	Human	PMID:16901789
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q8NHG7	Human	PMID:17872946
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:P51572	Human	PMID:18555783
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:O00237	Human	PMID:18675248
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:O75460	Human	PMID:19135427
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q9BZV1	Human	PMID:19275885
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q5VVQ6	Human	PMID:19818707
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:P35354	Human	PMID:24089527
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:P17861-1	Human	PMID:25239945
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q8TCT9	Human	PMID:25239945
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q9BQ70	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q8TCD1	Human	PMID:29275994
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:O15552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q05329	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q13049	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q53QW1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q6PL24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q8IWU4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q8N6L0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q8TB40	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q8TBB6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q96PJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q9H5X1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q9UHI5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DERL1	IPI	UniProtKB:Q9Y385	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Derl1	IPI	UniProtKB:Q9QYI6	Mouse	MGI:MGI:5499714|PMID:22267725
Molecular Function	GO:0005515	protein binding	Derl1	IPI	UniProtKB:Q9D024	Mouse	MGI:MGI:5605216|PMID:25009997
Molecular Function	GO:0044877	protein-containing complex binding	DERL1	IPI	GO:0005785	Human	PMID:26565908
Molecular Function	GO:0005047	signal recognition particle binding	DERL1	IDA		Human	PMID:26565908
Molecular Function	GO:0031625	ubiquitin protein ligase binding	DERL1	IPI	UniProtKB:Q96GF1	Human	PMID:24019521
Molecular Function	GO:0031625	ubiquitin protein ligase binding	DERL1	IPI	UniProtKB:Q99942	Human	PMID:24019521
Molecular Function	GO:1990381	ubiquitin-specific protease binding	DERL1	IPI	UniProtKB:P54252	Human	PMID:17000876
Cellular Component	GO:0036513	Derlin-1 retrotranslocation complex	DERL1	IDA		Human	PMID:15215856
Cellular Component	GO:0036513	Derlin-1 retrotranslocation complex	DERL1	IDA		Human	PMID:17872946
Cellular Component	GO:0036513	Derlin-1 retrotranslocation complex	DERL1	IDA		Human	PMID:25239945
Cellular Component	GO:0036502	Derlin-1-VIMP complex	DERL1	IDA		Human	PMID:15215856
Cellular Component	GO:0005769	early endosome	Derl1	IDA		Mouse	PMID:19509052
Cellular Component	GO:0005783	endoplasmic reticulum	DERL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	DERL1	IDA		Human	PMID:15215855
Cellular Component	GO:0005783	endoplasmic reticulum	DERL1	IDA		Human	PMID:16186510
Cellular Component	GO:0005783	endoplasmic reticulum	DERL1	IMP		Human	PMID:16449189
Cellular Component	GO:0005783	endoplasmic reticulum	Derl1	IDA		Mouse	PMID:19509052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	DERL1	IDA		Human	PMID:15215856
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	Derl1	IDA		Mouse	MGI:MGI:6467686|PMID:23233672
Cellular Component	GO:0005770	late endosome	Derl1	IDA		Mouse	PMID:19509052
Cellular Component	GO:0016020	membrane	DERL1	IDA		Human	PMID:15215855
Cellular Component	GO:0016020	membrane	DERL1	HDA		Human	PMID:19946888
Biological Process	GO:0034620	cellular response to unfolded protein	Derl1	IMP		Mouse	PMID:19509052
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	DERL1	IDA		Human	PMID:15215856
Biological Process	GO:0071712	ER-associated misfolded protein catabolic process	DERL1	IMP		Human	PMID:24089527
Biological Process	GO:0036503	ERAD pathway	DERL1	IMP		Human	PMID:25239945
Biological Process	GO:0032092	positive regulation of protein binding	DERL1	IMP		Human	PMID:24089527
Biological Process	GO:0031398	positive regulation of protein ubiquitination	DERL1	IDA		Human	PMID:24089527
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Derl1	IMP		Mouse	MGI:MGI:5780912|PMID:26692333
Biological Process	GO:0031648	protein destabilization	DERL1	IMP		Human	PMID:25239945
Biological Process	GO:0006986	response to unfolded protein	DERL1	IMP		Human	PMID:15215855
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	DERL1	IMP		Human	PMID:15215855
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	DERL1	IDA		Human	PMID:15215856
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	DERL1	IMP		Human	PMID:25660456
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	DERL1	IDA		Human	PMID:15215856
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	DERL1	IDA		Human	PMID:17872946
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	DERL1	IMP		Human	PMID:18555783

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern