Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DET1
  • Mouse genes Det1
  • Rat genes Det1
  • Zfish genes det1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Det1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DET1	IPI	UniProtKB:Q16531	Human	PMID:14739464
Molecular Function	GO:0005515	protein binding	DET1	IPI	UniProtKB:Q8NHY2	Human	PMID:14739464
Molecular Function	GO:0005515	protein binding	DET1	IPI	UniProtKB:Q13619,UniProtKB:Q16531	Human	PMID:16949367
Molecular Function	GO:0044877	protein-containing complex binding	DET1	IDA		Human	PMID:14739464
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	DET1	IPI	UniProtKB:Q16531,UniProtKB:Q8NHY2	Human	PMID:14739464
Molecular Function	GO:0031625	ubiquitin protein ligase binding	DET1	IMP		Human	PMID:14739464
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	DET1	IDA		Human	PMID:16949367
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	DET1	IDA		Human	PMID:14739464
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	DET1	IPI	UniProtKB:Q8NHY2	Human	PMID:14739464
Biological Process	GO:0016567	protein ubiquitination	DET1	IPI	UniProtKB:Q8NHY2	Human	PMID:14739464
Biological Process	GO:0065003	protein-containing complex assembly	DET1	IDA		Human	PMID:14739464

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern