Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DGKI
  • Mouse genes Dgki
  • Rat genes Dgki
  • Zfish genes dgki
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dgki

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004143	diacylglycerol kinase activity	DGKI	IDA		Human	PMID:9830018
Molecular Function	GO:0004143	diacylglycerol kinase activity	Dgki	IDA		Mouse	PMID:15894621
Molecular Function	GO:0004143	diacylglycerol kinase activity	Dgki	IDA		Rat	PMID:15024004|RGD:1302915
Molecular Function	GO:0005095	GTPase inhibitor activity	Dgki	IDA		Mouse	PMID:15894621
Molecular Function	GO:0005095	GTPase inhibitor activity	Dgki	IMP		Mouse	PMID:15894621
Molecular Function	GO:0005515	protein binding	DGKI	IPI	UniProtKB:P40337-3	Human	PMID:17986458
Molecular Function	GO:0005515	protein binding	Dgki	IPI	UniProtKB:P31016	Rat	PMID:21119615|RGD:8554416
Molecular Function	GO:0005515	protein binding	Dgki	IPI	UniProtKB:Q62696	Rat	PMID:21119615|RGD:8554416
Molecular Function	GO:0005515	protein binding	Dgki	IPI	UniProtKB:Q62936	Rat	PMID:21119615|RGD:8554416
Molecular Function	GO:0005515	protein binding	Dgki	IPI	UniProtKB:Q63622	Rat	PMID:21119615|RGD:8554416
Molecular Function	GO:0031267	small GTPase binding	Dgki	IPI	RefSeq:NP_997129	Mouse	PMID:15894621
Cellular Component	GO:0043679	axon terminus	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0005737	cytoplasm	DGKI	IDA		Human	PMID:9830018
Cellular Component	GO:0005737	cytoplasm	Dgki	IDA		Mouse	PMID:15894621
Cellular Component	GO:0005737	cytoplasm	Dgki	IDA		Rat	PMID:15024004|RGD:1302915
Cellular Component	GO:0005829	cytosol	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0043197	dendritic spine	DGKI	IDA		Human	PMID:21119615
Cellular Component	GO:0060076	excitatory synapse	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0099147	extrinsic component of postsynaptic density membrane	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0098891	extrinsic component of presynaptic active zone membrane	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0098978	glutamatergic synapse	Dgki	IMP		Mouse	PMID:21119615
Cellular Component	GO:0098978	glutamatergic synapse	Dgki	IDA		Mouse	PMID:21119615
Cellular Component	GO:0098978	glutamatergic synapse	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	Dgki	IDA		Mouse	PMID:15894621
Cellular Component	GO:0043025	neuronal cell body	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0005634	nucleus	DGKI	IDA		Human	PMID:9830018
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Dgki	IDA		Mouse	PMID:15894621
Cellular Component	GO:0014069	postsynaptic density	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0098793	presynapse	Dgki	IDA		Mouse	MGI:MGI:4936793|PMID:21119615
Cellular Component	GO:0048786	presynaptic active zone	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0032991	protein-containing complex	DGKI	IDA		Human	PMID:21119615
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Dgki	IMP		Mouse	PMID:21119615
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Dgki	IDA		Mouse	PMID:21119615
Cellular Component	GO:0045202	synapse	DGKI	IDA		Human	PMID:21119615
Cellular Component	GO:0097060	synaptic membrane	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0008021	synaptic vesicle	Dgki	IDA		Rat	PMID:21119615|RGD:8554416
Biological Process	GO:0046339	diacylglycerol metabolic process	Dgki	IDA		Rat	PMID:15024004|RGD:1302915
Biological Process	GO:0060079	excitatory postsynaptic potential	Dgki	IMP	MGI:MGI:3584141	Mouse	PMID:21119615
Biological Process	GO:0046959	habituation	Dgki	IMP	MGI:MGI:3584141	Mouse	PMID:21119615
Biological Process	GO:0046834	lipid phosphorylation	DGKI	IDA		Human	PMID:9830018
Biological Process	GO:0046834	lipid phosphorylation	Dgki	IDA		Rat	PMID:15024004|RGD:1302915
Biological Process	GO:0007269	neurotransmitter secretion	Dgki	IMP	MGI:MGI:3584141	Mouse	PMID:21119615
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	Dgki	IDA		Rat	PMID:15024004|RGD:1302915
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	Dgki	IMP	MGI:MGI:3584141	Mouse	PMID:15894621
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Dgki	IDA		Mouse	PMID:21119615
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Dgki	IMP		Mouse	PMID:21119615
Biological Process	GO:0007265	Ras protein signal transduction	Dgki	IMP	MGI:MGI:3584141	Mouse	PMID:15894621
Biological Process	GO:0043087	regulation of GTPase activity	Dgki	IMP	MGI:MGI:3584141	Mouse	PMID:15894621
Biological Process	GO:1900452	regulation of long-term synaptic depression	Dgki	IMP	MGI:MGI:3584141	Mouse	PMID:21119615
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	Dgki	IMP	MGI:MGI:3584141	Mouse	PMID:21119615

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern