Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Dgkz

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes DGKZ
- Mouse genes Dgkz
- Rat genes Dgkz
- Zfish genes dgkza,dgkzb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dgkz

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004143	diacylglycerol kinase activity	DGKZ	IDA		Human	PMID:15544348
Molecular Function	GO:0004143	diacylglycerol kinase activity	DGKZ	IDA		Human	PMID:18004883
Molecular Function	GO:0004143	diacylglycerol kinase activity	DGKZ	IDA		Human	PMID:19744926
Molecular Function	GO:0004143	diacylglycerol kinase activity	DGKZ	IDA		Human	PMID:22627129
Molecular Function	GO:0004143	diacylglycerol kinase activity	Dgkz	IMP		Mouse	MGI:MGI:2672999\|PMID:12883552
Molecular Function	GO:0004143	diacylglycerol kinase activity	Dgkz	IDA		Rat	PMID:8855332\|RGD:70715
Molecular Function	GO:0004857	enzyme inhibitor activity	Dgkz	IDA		Mouse	PMID:15894621
Molecular Function	GO:0016301	kinase activity	DGKZ	IDA		Human	PMID:18004883
Molecular Function	GO:0005515	protein binding	DGKZ	IPI	UniProtKB:Q99755	Human	PMID:15157668
Molecular Function	GO:0005515	protein binding	DGKZ	IPI	UniProtKB:Q13285	Human	PMID:17664281
Molecular Function	GO:0005515	protein binding	Dgkz	IPI	UniProtKB:P13405	Mouse	MGI:MGI:3694175\|PMID:16286473
Molecular Function	GO:0005515	protein binding	Dgkz	IPI	UniProtKB:P35569\|UniProtKB:P35570	Mouse	MGI:MGI:6201900\|PMID:27739494
Molecular Function	GO:0005515	protein binding	Dgkz	IPI	UniProtKB:D3ZSI8	Rat	PMID:15157668\|RGD:13792527
Molecular Function	GO:0005515	protein binding	Dgkz	IPI	UniProtKB:P31016	Rat	PMID:19229292\|RGD:8553523
Molecular Function	GO:0005515	protein binding	Dgkz	IPI	UniProtKB:Q62696	Rat	PMID:19229292\|RGD:8553523
Molecular Function	GO:0005515	protein binding	Dgkz	IPI	UniProtKB:Q62936	Rat	PMID:19229292\|RGD:8553523
Molecular Function	GO:0005515	protein binding	Dgkz	IPI	UniProtKB:Q63622	Rat	PMID:19229292\|RGD:8553523
Molecular Function	GO:0005515	protein binding	Dgkz	IPI	RGD:71094	Rat	PMID:24893663\|RGD:9590077
Cellular Component	GO:0005829	cytosol	DGKZ	IDA		Human	PMID:22627129
Cellular Component	GO:0098978	glutamatergic synapse	Dgkz	IDA		Mouse	PMID:19229292
Cellular Component	GO:0098978	glutamatergic synapse	Dgkz	IMP		Mouse	PMID:19229292
Cellular Component	GO:0098978	glutamatergic synapse	Dgkz	IEP		Mouse	PMID:19229292
Cellular Component	GO:0098978	glutamatergic synapse	Dgkz	IDA		Rat	PMID:19229292\|RGD:8553523
Cellular Component	GO:0030027	lamellipodium	DGKZ	IDA		Human	PMID:15157668
Cellular Component	GO:0016607	nuclear speck	DGKZ	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DGKZ	IDA		Human	PMID:15157668
Cellular Component	GO:0005634	nucleus	DGKZ	IDA		Human	PMID:17664281
Cellular Component	GO:0005634	nucleus	Dgkz	IDA		Rat	PMID:8855332\|RGD:70715
Cellular Component	GO:0014069	postsynaptic density	Dgkz	IDA		Rat	PMID:19229292\|RGD:8553523
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Dgkz	IDA		Mouse	PMID:19229292
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Dgkz	IMP		Mouse	PMID:19229292
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Dgkz	IEP		Mouse	PMID:19229292
Biological Process	GO:0046339	diacylglycerol metabolic process	DGKZ	IDA		Human	PMID:15544348
Biological Process	GO:0046339	diacylglycerol metabolic process	DGKZ	IDA		Human	PMID:19744926
Biological Process	GO:0046339	diacylglycerol metabolic process	DGKZ	IDA		Human	PMID:22627129
Biological Process	GO:0046339	diacylglycerol metabolic process	Dgkz	IMP		Mouse	MGI:MGI:2672999\|PMID:12883552
Biological Process	GO:0046486	glycerolipid metabolic process	DGKZ	IDA		Human	PMID:22627129
Biological Process	GO:0046834	lipid phosphorylation	DGKZ	IDA		Human	PMID:15544348
Biological Process	GO:0046834	lipid phosphorylation	DGKZ	IDA		Human	PMID:18004883
Biological Process	GO:0046834	lipid phosphorylation	DGKZ	IDA		Human	PMID:19744926
Biological Process	GO:0046834	lipid phosphorylation	DGKZ	IDA		Human	PMID:22627129
Biological Process	GO:0046834	lipid phosphorylation	Dgkz	IMP		Mouse	MGI:MGI:2672999\|PMID:12883552
Biological Process	GO:0099562	maintenance of postsynaptic density structure	Dgkz	IDA		Mouse	PMID:19229292
Biological Process	GO:0099562	maintenance of postsynaptic density structure	Dgkz	IMP		Mouse	PMID:19229292
Biological Process	GO:0099562	maintenance of postsynaptic density structure	Dgkz	IEP		Mouse	PMID:19229292
Biological Process	GO:0046580	negative regulation of Ras protein signal transduction	Dgkz	IMP	MGI:MGI:2674915	Mouse	PMID:15894621
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	Dgkz	IMP		Mouse	MGI:MGI:2672999\|PMID:12883552
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	DGKZ	IDA		Human	PMID:15544348
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	DGKZ	IDA		Human	PMID:19744926
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	Dgkz	IMP		Mouse	MGI:MGI:6201900\|PMID:27739494
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	Dgkz	IMP		Mouse	MGI:MGI:2672999\|PMID:12883552
Biological Process	GO:0090216	positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	DGKZ	IMP		Human	PMID:15157668
Biological Process	GO:0090216	positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	Dgkz	IMP		Mouse	MGI:MGI:6201900\|PMID:27739494
Biological Process	GO:0007265	Ras protein signal transduction	Dgkz	IMP	MGI:MGI:2674915	Mouse	PMID:15894621

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.