Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DHX33
  • Mouse genes Dhx33
  • Rat genes Dhx33
  • Zfish genes dhx33
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dhx33

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Dhx33	IPI	UniProtKB:P17480	Mouse	MGI:MGI:5300123|PMID:21930779
Molecular Function	GO:0003725	double-stranded RNA binding	DHX33	IDA		Human	PMID:23871209
Molecular Function	GO:0003725	double-stranded RNA binding	Dhx33	IDA		Mouse	MGI:MGI:6120210|PMID:24037184
Molecular Function	GO:0003729	mRNA binding	DHX33	IDA		Human	PMID:26100019
Molecular Function	GO:0005515	protein binding	DHX33	IPI	UniProtKB:Q96P20	Human	PMID:23871209
Molecular Function	GO:0005515	protein binding	DHX33	IPI	UniProtKB:O00571|UniProtKB:O15372|UniProtKB:O75821	Human	PMID:26100019
Molecular Function	GO:0005515	protein binding	DHX33	IPI	UniProtKB:Q9H6R0	Human	PMID:26100019
Molecular Function	GO:0005515	protein binding	Dhx33	IPI	UniProtKB:Q8VCF0	Mouse	MGI:MGI:6120210|PMID:24037184
Molecular Function	GO:0000182	rDNA binding	DHX33	IDA		Human	PMID:21930779
Molecular Function	GO:0000182	rDNA binding	Dhx33	IDA		Mouse	MGI:MGI:5300123|PMID:21930779
Molecular Function	GO:0043023	ribosomal large subunit binding	DHX33	IPI	UniProtKB:P39023|UniProtKB:P61254|UniProtKB:P61353|UniProtKB:Q9H6R0	Human	PMID:26100019
Molecular Function	GO:0003723	RNA binding	DHX33	HDA		Human	PMID:22658674
Cellular Component	GO:0005737	cytoplasm	DHX33	IDA		Human	PMID:23871209
Cellular Component	GO:0072559	NLRP3 inflammasome complex	DHX33	IDA		Human	PMID:23871209
Cellular Component	GO:0005730	nucleolus	DHX33	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	DHX33	IDA		Human	PMID:21930779
Cellular Component	GO:0005730	nucleolus	Dhx33	IDA		Mouse	MGI:MGI:5300123|PMID:21930779
Cellular Component	GO:0005654	nucleoplasm	DHX33	IDA		Human	PMID:21930779
Cellular Component	GO:0005654	nucleoplasm	Dhx33	IDA		Mouse	MGI:MGI:5300123|PMID:21930779
Cellular Component	GO:0005634	nucleus	DHX33	IDA		Human	PMID:23871209
Biological Process	GO:0043410	positive regulation of MAPK cascade	Dhx33	IMP		Mouse	MGI:MGI:6120210|PMID:24037184
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Dhx33	IMP		Mouse	MGI:MGI:6120210|PMID:24037184
Biological Process	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	DHX33	IDA		Human	PMID:23871209
Biological Process	GO:0045943	positive regulation of transcription by RNA polymerase I	DHX33	IDA		Human	PMID:21930779
Biological Process	GO:0045943	positive regulation of transcription by RNA polymerase I	Dhx33	IDA		Mouse	MGI:MGI:5300123|PMID:21930779
Biological Process	GO:0032481	positive regulation of type I interferon production	Dhx33	IMP		Mouse	MGI:MGI:6120210|PMID:24037184
Biological Process	GO:0006356	regulation of transcription by RNA polymerase I	dhx33	IMP	ZFIN:ZDB-GENO-170209-20	Zfish	PMID:27601587
Biological Process	GO:0006413	translational initiation	Dhx33	IDA		Mouse	MGI:MGI:6120061|PMID:26100019

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern