Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DHX36
  • Mouse genes Dhx36
  • Rat genes Dhx36
  • Zfish genes dhx36
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dhx36

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	DHX36	IDA		Human	PMID:21586581
Molecular Function	GO:0003678	DNA helicase activity	DHX36	IDA		Human	PMID:16150737
Molecular Function	GO:0003678	DNA helicase activity	DHX36	IDA		Human	PMID:18842585
Molecular Function	GO:0003678	DNA helicase activity	DHX36	IDA		Human	PMID:25579584
Molecular Function	GO:0003678	DNA helicase activity	Dhx36	IMP		Mouse	MGI:MGI:6201778|PMID:25611385
Molecular Function	GO:0003725	double-stranded RNA binding	DHX36	IDA		Human	PMID:21266579
Molecular Function	GO:0003725	double-stranded RNA binding	Dhx36	IDA		Mouse	PMID:21703541
Molecular Function	GO:0051880	G-quadruplex DNA binding	DHX36	IDA		Human	PMID:16150737
Molecular Function	GO:0051880	G-quadruplex DNA binding	DHX36	IDA		Human	PMID:18842585
Molecular Function	GO:0051880	G-quadruplex DNA binding	DHX36	IDA		Human	PMID:21586581
Molecular Function	GO:0051880	G-quadruplex DNA binding	DHX36	IDA		Human	PMID:21993297
Molecular Function	GO:0051880	G-quadruplex DNA binding	DHX36	IDA		Human	PMID:24151078
Molecular Function	GO:0051880	G-quadruplex DNA binding	Dhx36	IDA		Mouse	MGI:MGI:6201778|PMID:25611385
Molecular Function	GO:0002151	G-quadruplex RNA binding	DHX36	IDA		Human	PMID:18842585
Molecular Function	GO:0002151	G-quadruplex RNA binding	DHX36	IDA		Human	PMID:20472641
Molecular Function	GO:0002151	G-quadruplex RNA binding	DHX36	IDA		Human	PMID:21149580
Molecular Function	GO:0002151	G-quadruplex RNA binding	DHX36	IDA		Human	PMID:21846770
Molecular Function	GO:0002151	G-quadruplex RNA binding	DHX36	IMP		Human	PMID:22238380
Molecular Function	GO:0002151	G-quadruplex RNA binding	DHX36	IDA		Human	PMID:24151078
Molecular Function	GO:0002151	G-quadruplex RNA binding	DHX36	IDA		Human	PMID:24369427
Molecular Function	GO:0002151	G-quadruplex RNA binding	DHX36	IDA		Human	PMID:25579584
Molecular Function	GO:0002151	G-quadruplex RNA binding	DHX36	IDA		Human	PMID:26489465
Molecular Function	GO:0002151	G-quadruplex RNA binding	DHX36	IMP		Human	PMID:27940037
Molecular Function	GO:0042826	histone deacetylase binding	Dhx36	IDA		Mouse	MGI:MGI:5559667|PMID:21590736
Molecular Function	GO:0000287	magnesium ion binding	DHX36	IDA		Human	PMID:16150737
Molecular Function	GO:0000287	magnesium ion binding	DHX36	IDA		Human	PMID:21846770
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	DHX36	IDA		Human	PMID:14731398
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	DHX36	IDA		Human	PMID:26489465
Molecular Function	GO:0003730	mRNA 3'-UTR binding	DHX36	IDA		Human	PMID:24369427
Molecular Function	GO:0048027	mRNA 5'-UTR binding	DHX36	IDA		Human	PMID:26489465
Molecular Function	GO:0070883	pre-miRNA binding	Dhx36	IDA		Rat	PMID:23651854|RGD:13792545
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:O95453	Human	PMID:14731398
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q01780	Human	PMID:14731398
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q12906	Human	PMID:14731398
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q15717	Human	PMID:14731398
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q9NQT5	Human	PMID:14731398
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q9UKV8	Human	PMID:17932509
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q9UL18	Human	PMID:17932509
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:O15379	Human	PMID:18279852
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:P17844	Human	PMID:18279852
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q13547	Human	PMID:18279852
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q92841	Human	PMID:18279852
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q99836	Human	PMID:20696886
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:O14746	Human	PMID:21846770
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:O60832	Human	PMID:21846770
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q03468	Human	PMID:26030138
Molecular Function	GO:0005515	protein binding	DHX36	IPI	UniProtKB:Q15717	Human	PMID:26489465
Molecular Function	GO:0005515	protein binding	Dhx36	IPI	UniProtKB:Q6NZM9	Mouse	MGI:MGI:5559667|PMID:21590736
Molecular Function	GO:0005515	protein binding	Dhx36	IPI	PR:Q9JIK5	Mouse	PMID:21703541
Molecular Function	GO:0003723	RNA binding	DHX36	IDA		Human	PMID:18854321
Molecular Function	GO:0003723	RNA binding	DHX36	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	DHX36	HDA		Human	PMID:22681889
Molecular Function	GO:0003724	RNA helicase activity	DHX36	IDA		Human	PMID:14731398
Molecular Function	GO:0003724	RNA helicase activity	DHX36	IDA		Human	PMID:18842585
Molecular Function	GO:0003724	RNA helicase activity	DHX36	IDA		Human	PMID:21846770
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	DHX36	IDA		Human	PMID:21586581
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	DHX36	IDA		Human	PMID:21993297
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Dhx36	IDA		Mouse	MGI:MGI:6201778|PMID:25611385
Molecular Function	GO:0003697	single-stranded DNA binding	DHX36	IDA		Human	PMID:20696886
Molecular Function	GO:0070034	telomerase RNA binding	DHX36	IDA		Human	PMID:21149580
Molecular Function	GO:0070034	telomerase RNA binding	DHX36	IDA		Human	PMID:21846770
Molecular Function	GO:0070034	telomerase RNA binding	DHX36	IDA		Human	PMID:22238380
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Dhx36	IDA		Mouse	MGI:MGI:5559667|PMID:21590736
Cellular Component	GO:0030424	axon	Dhx36	IDA		Rat	PMID:23651854|RGD:13792545
Cellular Component	GO:0000781	chromosome, telomeric region	DHX36	IDA		Human	PMID:20472641
Cellular Component	GO:0000781	chromosome, telomeric region	DHX36	IDA		Human	PMID:21846770
Cellular Component	GO:0005737	cytoplasm	DHX36	IDA		Human	PMID:14731398
Cellular Component	GO:0005737	cytoplasm	DHX36	IDA		Human	PMID:18279852
Cellular Component	GO:0005737	cytoplasm	DHX36	IDA		Human	PMID:18854321
Cellular Component	GO:0005737	cytoplasm	DHX36	IDA		Human	PMID:20696886
Cellular Component	GO:0010494	cytoplasmic stress granule	DHX36	IDA		Human	PMID:18854321
Cellular Component	GO:0005829	cytosol	DHX36	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Dhx36	IDA		Mouse	MGI:MGI:5050760|PMID:21703541
Cellular Component	GO:0030425	dendrite	Dhx36	IDA		Rat	PMID:23651854|RGD:13792545
Cellular Component	GO:0070062	extracellular exosome	DHX36	HDA		Human	PMID:18570454
Cellular Component	GO:0005739	mitochondrion	DHX36	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	DHX36	IDA		Human	PMID:18279852
Cellular Component	GO:0005654	nucleoplasm	DHX36	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DHX36	IDA		Human	PMID:14731398
Cellular Component	GO:0005634	nucleus	DHX36	IDA		Human	PMID:18279852
Cellular Component	GO:0005634	nucleus	DHX36	IDA		Human	PMID:18854321
Cellular Component	GO:0043204	perikaryon	Dhx36	IDA		Rat	PMID:23651854|RGD:13792545
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	DHX36	IMP		Human	PMID:26489465
Biological Process	GO:1903843	cellular response to arsenite ion	DHX36	IDA		Human	PMID:18854321
Biological Process	GO:0034605	cellular response to heat	DHX36	IDA		Human	PMID:18854321
Biological Process	GO:0034644	cellular response to UV	DHX36	IMP		Human	PMID:27940037
Biological Process	GO:0044806	G-quadruplex DNA unwinding	DHX36	IDA		Human	PMID:16150737
Biological Process	GO:0044806	G-quadruplex DNA unwinding	DHX36	IDA		Human	PMID:18842585
Biological Process	GO:0044806	G-quadruplex DNA unwinding	Dhx36	IDA		Mouse	MGI:MGI:6201778|PMID:25611385
Biological Process	GO:0017148	negative regulation of translation	DHX36	IDA		Human	PMID:24369427
Biological Process	GO:0001503	ossification	Dhx36	IMP		Mouse	MGI:MGI:5559667|PMID:21590736
Biological Process	GO:0051891	positive regulation of cardioblast differentiation	Dhx36	IMP		Mouse	MGI:MGI:6201954|PMID:26489465
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	DHX36	IMP		Human	PMID:26489465
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	Dhx36	IMP		Rat	PMID:23651854|RGD:13792545
Biological Process	GO:0010628	positive regulation of gene expression	Dhx36	IMP		Rat	PMID:23651854|RGD:13792545
Biological Process	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation	Dhx36	IMP		Mouse	MGI:MGI:5427564|PMID:22422825
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Dhx36	IMP		Mouse	MGI:MGI:5050760|PMID:21703541
Biological Process	GO:0032727	positive regulation of interferon-alpha production	DHX36	IMP		Human	PMID:20696886
Biological Process	GO:1904582	positive regulation of intracellular mRNA localization	Dhx36	IMP		Rat	PMID:23651854|RGD:13792545
Biological Process	GO:0031442	positive regulation of mRNA 3'-end processing	DHX36	IMP		Human	PMID:27940037
Biological Process	GO:0002735	positive regulation of myeloid dendritic cell cytokine production	Dhx36	IMP		Mouse	MGI:MGI:5050760|PMID:21703541
Biological Process	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	DHX36	IMP		Human	PMID:14731398
Biological Process	GO:0032206	positive regulation of telomere maintenance	DHX36	IMP		Human	PMID:22238380
Biological Process	GO:1904358	positive regulation of telomere maintenance via telomere lengthening	DHX36	IMP		Human	PMID:21149580
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Dhx36	IMP		Mouse	MGI:MGI:6201778|PMID:25611385
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Dhx36	IDA		Mouse	MGI:MGI:5559667|PMID:21590736
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	DHX36	IMP		Human	PMID:21993297
Biological Process	GO:0045995	regulation of embryonic development	Dhx36	IMP		Mouse	MGI:MGI:5427564|PMID:22422825
Biological Process	GO:0043488	regulation of mRNA stability	DHX36	IMP		Human	PMID:18279852
Biological Process	GO:0006359	regulation of transcription by RNA polymerase III	DHX36	IMP		Human	PMID:18279852
Biological Process	GO:0043330	response to exogenous dsRNA	Dhx36	IMP		Mouse	PMID:21703541
Biological Process	GO:0009615	response to virus	Dhx36	IMP		Mouse	PMID:21703541
Biological Process	GO:0010501	RNA secondary structure unwinding	DHX36	IDA		Human	PMID:18842585
Biological Process	GO:0010501	RNA secondary structure unwinding	DHX36	IDA		Human	PMID:20472641
Biological Process	GO:0010501	RNA secondary structure unwinding	DHX36	IDA		Human	PMID:21149580
Biological Process	GO:0010501	RNA secondary structure unwinding	DHX36	IDA		Human	PMID:21846770
Biological Process	GO:0010501	RNA secondary structure unwinding	DHX36	IDA		Human	PMID:22238380
Biological Process	GO:0007283	spermatogenesis	Dhx36	IDA		Mouse	MGI:MGI:6201778|PMID:25611385
Biological Process	GO:0090669	telomerase RNA stabilization	DHX36	IDA		Human	PMID:22238380

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern