Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DHX8
  • Mouse genes Dhx8
  • Rat genes Dhx8
  • Zfish genes dhx8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dhx8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	DHX8	IPI	UniProtKB:Q14562	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	DHX8	IPI	UniProtKB:P32121	Human	PMID:16820410
Molecular Function	GO:0005515	protein binding	DHX8	IPI	UniProtKB:Q8IWX8	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	DHX8	IPI	UniProtKB:Q8N5F7	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	DHX8	IPI	UniProtKB:Q9ULR0	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	DHX8	IPI	UniProtKB:Q96SB4	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	DHX8	IPI	UniProtKB:Q96SB4	Human	PMID:28514442
Molecular Function	GO:0003723	RNA binding	DHX8	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	DHX8	HDA		Human	PMID:22681889
Cellular Component	GO:0071013	catalytic step 2 spliceosome	DHX8	IDA		Human	PMID:11991638
Cellular Component	GO:0005829	cytosol	DHX8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	DHX8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DHX8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DHX8	IDA		Human	PMID:28062851
Cellular Component	GO:0005634	nucleus	DHX8	IDA		Human	PMID:28076346
Cellular Component	GO:0005634	nucleus	dhx8	IDA		Zfish	PMID:22411201
Cellular Component	GO:0071007	U2-type catalytic step 2 spliceosome	DHX8	IDA		Human	PMID:28076346
Biological Process	GO:0051301	cell division	dhx8	IMP	ZFIN:ZDB-GENO-120606-12	Zfish	PMID:22411201
Biological Process	GO:0070054	mRNA splicing, via endonucleolytic cleavage and ligation	dhx8	IMP	ZFIN:ZDB-GENO-120606-12	Zfish	PMID:22411201
Biological Process	GO:0000398	mRNA splicing, via spliceosome	DHX8	IDA		Human	PMID:28076346
Biological Process	GO:0060215	primitive hemopoiesis	dhx8	IMP	ZFIN:ZDB-GENO-120606-12	Zfish	PMID:22411201

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern