Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DHX9
  • Mouse genes Dhx9
  • Rat genes Dhx9
  • Zfish genes dhx9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dhx9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043138	3'-5' DNA helicase activity	DHX9	IDA		Human	PMID:21561811
Molecular Function	GO:0033679	3'-5' DNA/RNA helicase activity	DHX9	IDA		Human	PMID:1537828
Molecular Function	GO:0033679	3'-5' DNA/RNA helicase activity	DHX9	IDA		Human	PMID:21561811
Molecular Function	GO:0034458	3'-5' RNA helicase activity	DHX9	IDA		Human	PMID:1537828
Molecular Function	GO:0034458	3'-5' RNA helicase activity	DHX9	IDA		Human	PMID:21561811
Molecular Function	GO:0005524	ATP binding	DHX9	IDA		Human	PMID:11416126
Molecular Function	GO:0016887	ATP hydrolysis activity	DHX9	IMP		Human	PMID:11416126
Molecular Function	GO:0031490	chromatin DNA binding	DHX9	IDA		Human	PMID:24049074
Molecular Function	GO:0003678	DNA helicase activity	DHX9	IMP		Human	PMID:12711669
Molecular Function	GO:0003688	DNA replication origin binding	DHX9	IDA		Human	PMID:24990949
Molecular Function	GO:0003690	double-stranded DNA binding	DHX9	IDA		Human	PMID:12711669
Molecular Function	GO:0003690	double-stranded DNA binding	DHX9	IDA		Human	PMID:9111062
Molecular Function	GO:0003725	double-stranded RNA binding	DHX9	IDA		Human	PMID:10198287
Molecular Function	GO:0003725	double-stranded RNA binding	DHX9	IDA		Human	PMID:12711669
Molecular Function	GO:0003725	double-stranded RNA binding	DHX9	IDA		Human	PMID:21957149
Molecular Function	GO:0003725	double-stranded RNA binding	DHX9	IDA		Human	PMID:27107641
Molecular Function	GO:0003725	double-stranded RNA binding	DHX9	IDA		Human	PMID:28636595
Molecular Function	GO:0003725	double-stranded RNA binding	DHX9	IDA		Human	PMID:9111062
Molecular Function	GO:0061676	importin-alpha family protein binding	DHX9	IDA		Human	PMID:16375861
Molecular Function	GO:0003729	mRNA binding	DHX9	IDA		Human	PMID:10198287
Molecular Function	GO:0003729	mRNA binding	DHX9	IMP		Human	PMID:28221134
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	DHX9	IDA		Human	PMID:1537828
Molecular Function	GO:1905538	polysome binding	DHX9	IDA		Human	PMID:16680162
Molecular Function	GO:1905538	polysome binding	DHX9	IDA		Human	PMID:21247876
Molecular Function	GO:1990841	promoter-specific chromatin binding	DHX9	IMP		Human	PMID:28221134
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9UBU9	Human	PMID:10924507
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9ULX6	Human	PMID:11402034
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P07910	Human	PMID:11687588
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P60709	Human	PMID:11687588
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P11388	Human	PMID:12711669
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P13010	Human	PMID:14704337
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q99873	Human	PMID:15084609
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q04206	Human	PMID:15355351
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9NZI8	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P16104	Human	PMID:17498979
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q15633	Human	PMID:17531811
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9UKV8	Human	PMID:17531811
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9UPY3	Human	PMID:17531811
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9HA38	Human	PMID:18519039
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9UBU9	Human	PMID:18596238
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:O14980	Human	PMID:19955415
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9UBU9	Human	PMID:20123736
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q99836	Human	PMID:20696886
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9H9Z2	Human	PMID:21247876
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P67809	Human	PMID:21849455
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P19525	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9BRS8	Human	PMID:22190748
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q15633	Human	PMID:23361462
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q9UKV8	Human	PMID:23361462
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:O60318	Human	PMID:23652018
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P67809	Human	PMID:23986595
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P52948	Human	PMID:28221134
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P55265	Human	PMID:28355180
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q7RTR0	Human	PMID:28636595
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q7Z7L1	Human	PMID:29395061
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:Q92793	Human	PMID:9323138
Molecular Function	GO:0005515	protein binding	DHX9	IPI	UniProtKB:P38398	Human	PMID:9662397
Molecular Function	GO:0005515	protein binding	Dhx9	IPI	UniProtKB:Q62520	Mouse	MGI:MGI:3771485|PMID:18068128
Molecular Function	GO:0005515	protein binding	Dhx9	IPI	UniProtKB:Q99MU3	Mouse	MGI:MGI:5908757|PMID:28355180
Molecular Function	GO:0005515	protein binding	Dhx9	IPI	PR:O54943	Mouse	PMID:22767893
Molecular Function	GO:0005515	protein binding	Dhx9	IPI	PR:Q61656	Mouse	PMID:22767893
Molecular Function	GO:0001069	regulatory region RNA binding	DHX9	IDA		Human	PMID:28355180
Molecular Function	GO:0001069	regulatory region RNA binding	Dhx9	IDA		Mouse	MGI:MGI:5908757|PMID:28355180
Molecular Function	GO:1905172	RISC complex binding	DHX9	IDA		Human	PMID:17531811
Molecular Function	GO:0003723	RNA binding	DHX9	IDA		Human	PMID:1537828
Molecular Function	GO:0003723	RNA binding	DHX9	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	DHX9	HDA		Human	PMID:22681889
Molecular Function	GO:0003724	RNA helicase activity	DHX9	IDA		Human	PMID:28221134
Molecular Function	GO:0070063	RNA polymerase binding	DHX9	IDA		Human	PMID:9323138
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	DHX9	IDA		Human	PMID:11038348
Molecular Function	GO:0000993	RNA polymerase II complex binding	DHX9	IDA		Human	PMID:11416126
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	DHX9	IPI	UniProtKB:Q8VI67	Human	PMID:17303075
Molecular Function	GO:0035613	RNA stem-loop binding	DHX9	IDA		Human	PMID:11096080
Molecular Function	GO:0035613	RNA stem-loop binding	DHX9	IDA		Human	PMID:16680162
Molecular Function	GO:1990825	sequence-specific mRNA binding	DHX9	IDA		Human	PMID:11402034
Molecular Function	GO:1990825	sequence-specific mRNA binding	DHX9	IDA		Human	PMID:9162007
Molecular Function	GO:1990518	single-stranded 3'-5' DNA helicase activity	DHX9	IDA		Human	PMID:20669935
Molecular Function	GO:1990518	single-stranded 3'-5' DNA helicase activity	DHX9	IDA		Human	PMID:24049074
Molecular Function	GO:0003697	single-stranded DNA binding	DHX9	IDA		Human	PMID:10198287
Molecular Function	GO:0003697	single-stranded DNA binding	DHX9	IDA		Human	PMID:20696886
Molecular Function	GO:0003697	single-stranded DNA binding	DHX9	IDA		Human	PMID:21957149
Molecular Function	GO:0003697	single-stranded DNA binding	DHX9	IDA		Human	PMID:9111062
Molecular Function	GO:0003727	single-stranded RNA binding	DHX9	IDA		Human	PMID:10198287
Molecular Function	GO:0003727	single-stranded RNA binding	DHX9	IDA		Human	PMID:9111062
Molecular Function	GO:0035197	siRNA binding	DHX9	IDA		Human	PMID:23361462
Molecular Function	GO:0003713	transcription coactivator activity	DHX9	IMP		Human	PMID:9323138
Molecular Function	GO:0003712	transcription coregulator activity	DHX9	IMP		Human	PMID:11416126
Molecular Function	GO:0045142	triplex DNA binding	DHX9	IDA		Human	PMID:24049074
Cellular Component	GO:0015629	actin cytoskeleton	DHX9	IDA		Human	PMID:11687588
Cellular Component	GO:0005813	centrosome	DHX9	IDA		Human	PMID:17498979
Cellular Component	GO:0070937	CRD-mediated mRNA stability complex	DHX9	IPI		Human	PMID:19029303
Cellular Component	GO:0070937	CRD-mediated mRNA stability complex	DHX9	IDA		Human	PMID:19029303
Cellular Component	GO:0005737	cytoplasm	DHX9	IDA		Human	PMID:10198287
Cellular Component	GO:0005737	cytoplasm	DHX9	IDA		Human	PMID:10207077
Cellular Component	GO:0005737	cytoplasm	DHX9	IDA		Human	PMID:16375861
Cellular Component	GO:0005737	cytoplasm	DHX9	IDA		Human	PMID:16680162
Cellular Component	GO:0005737	cytoplasm	DHX9	IDA		Human	PMID:20696886
Cellular Component	GO:0005737	cytoplasm	DHX9	IDA		Human	PMID:9162007
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	DHX9	IDA		Human	PMID:10198287
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	DHX9	IDA		Human	PMID:15121898
Cellular Component	GO:0005829	cytosol	DHX9	IDA		Human	PMID:19029303
Cellular Component	GO:0016020	membrane	DHX9	HDA		Human	PMID:16210410
Cellular Component	GO:0016020	membrane	DHX9	HDA		Human	PMID:19946888
Cellular Component	GO:0016604	nuclear body	DHX9	IDA		Human	PMID:28221134
Cellular Component	GO:0097165	nuclear stress granule	DHX9	IDA		Human	PMID:10198287
Cellular Component	GO:0097165	nuclear stress granule	DHX9	IMP		Human	PMID:24965446
Cellular Component	GO:0005730	nucleolus	DHX9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	Dhx9	IDA		Mouse	PMID:14729462
Cellular Component	GO:0005654	nucleoplasm	DHX9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DHX9	IDA		Human	PMID:28221134
Cellular Component	GO:0005634	nucleus	DHX9	IDA		Human	PMID:10198287
Cellular Component	GO:0005634	nucleus	DHX9	IDA		Human	PMID:10207077
Cellular Component	GO:0005634	nucleus	DHX9	IDA		Human	PMID:11687588
Cellular Component	GO:0005634	nucleus	DHX9	IDA		Human	PMID:15121898
Cellular Component	GO:0005634	nucleus	DHX9	IDA		Human	PMID:16375861
Cellular Component	GO:0005634	nucleus	DHX9	IDA		Human	PMID:16680162
Cellular Component	GO:0005634	nucleus	DHX9	IDA		Human	PMID:17498979
Cellular Component	GO:0005634	nucleus	DHX9	IDA		Human	PMID:24965446
Cellular Component	GO:0005634	nucleus	DHX9	IDA		Human	PMID:9162007
Cellular Component	GO:0005726	perichromatin fibrils	DHX9	IDA		Human	PMID:10198287
Cellular Component	GO:0042788	polysomal ribosome	DHX9	IDA		Human	PMID:16680162
Cellular Component	GO:0005844	polysome	DHX9	IDA		Human	PMID:21247876
Cellular Component	GO:0005844	polysome	DHX9	IDA		Human	PMID:22190748
Cellular Component	GO:0032991	protein-containing complex	DHX9	IDA		Human	PMID:11687588
Cellular Component	GO:1990904	ribonucleoprotein complex	DHX9	IDA		Human	PMID:11402034
Cellular Component	GO:1990904	ribonucleoprotein complex	DHX9	IDA		Human	PMID:12711669
Cellular Component	GO:1990904	ribonucleoprotein complex	DHX9	IDA		Human	PMID:14704337
Cellular Component	GO:1990904	ribonucleoprotein complex	DHX9	IDA		Human	PMID:16680162
Cellular Component	GO:1990904	ribonucleoprotein complex	DHX9	IDA		Human	PMID:17289661
Cellular Component	GO:1990904	ribonucleoprotein complex	DHX9	IDA		Human	PMID:18809582
Cellular Component	GO:1990904	ribonucleoprotein complex	DHX9	IDA		Human	PMID:22190748
Cellular Component	GO:1990904	ribonucleoprotein complex	DHX9	IMP		Human	PMID:28221134
Cellular Component	GO:0016442	RISC complex	DHX9	IDA		Human	PMID:17531811
Cellular Component	GO:0070578	RISC-loading complex	DHX9	IMP		Human	PMID:17531811
Biological Process	GO:0000380	alternative mRNA splicing, via spliceosome	DHX9	IMP		Human	PMID:28221134
Biological Process	GO:0071360	cellular response to exogenous dsRNA	DHX9	IMP		Human	PMID:21957149
Biological Process	GO:0034605	cellular response to heat	Dhx9	IDA		Mouse	PMID:18755693
Biological Process	GO:0071356	cellular response to tumor necrosis factor	DHX9	IMP		Human	PMID:15355351
Biological Process	GO:0007623	circadian rhythm	Dhx9	IMP		Mouse	PMID:22767893
Biological Process	GO:0070934	CRD-mediated mRNA stabilization	DHX9	IDA		Human	PMID:19029303
Biological Process	GO:0070934	CRD-mediated mRNA stabilization	DHX9	IMP		Human	PMID:19029303
Biological Process	GO:0032508	DNA duplex unwinding	DHX9	IMP		Human	PMID:12711669
Biological Process	GO:0032508	DNA duplex unwinding	DHX9	IDA		Human	PMID:21561811
Biological Process	GO:0032508	DNA duplex unwinding	DHX9	IDA		Human	PMID:9111062
Biological Process	GO:0039695	DNA-templated viral transcription	DHX9	IDA		Human	PMID:11096080
Biological Process	GO:0044806	G-quadruplex DNA unwinding	DHX9	IDA		Human	PMID:21561811
Biological Process	GO:0098795	global gene silencing by mRNA cleavage	DHX9	IMP		Human	PMID:17531811
Biological Process	GO:1900152	negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	DHX9	IDA		Human	PMID:19029303
Biological Process	GO:0001649	osteoblast differentiation	DHX9	HDA		Human	PMID:16210410
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	DHX9	IMP		Human	PMID:16680162
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	DHX9	IDA		Human	PMID:19029303
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	DHX9	IMP		Human	PMID:21247876
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	DHX9	IMP		Human	PMID:22190748
Biological Process	GO:0045739	positive regulation of DNA repair	DHX9	IMP		Human	PMID:24049074
Biological Process	GO:0045740	positive regulation of DNA replication	DHX9	IMP		Human	PMID:24990949
Biological Process	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	DHX9	IMP		Human	PMID:12711669
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	DHX9	IMP		Human	PMID:24990949
Biological Process	GO:0050729	positive regulation of inflammatory response	Dhx9	IMP		Mouse	MGI:MGI:5908739|PMID:28636595
Biological Process	GO:0045089	positive regulation of innate immune response	Dhx9	IMP		Mouse	MGI:MGI:5908739|PMID:28636595
Biological Process	GO:0032727	positive regulation of interferon-alpha production	DHX9	IMP		Human	PMID:21957149
Biological Process	GO:0032728	positive regulation of interferon-beta production	DHX9	IMP		Human	PMID:21957149
Biological Process	GO:0032741	positive regulation of interleukin-18 production	Dhx9	IMP		Mouse	MGI:MGI:5908739|PMID:28636595
Biological Process	GO:0032755	positive regulation of interleukin-6 production	DHX9	IMP		Human	PMID:20696886
Biological Process	GO:0032755	positive regulation of interleukin-6 production	DHX9	IMP		Human	PMID:21957149
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	DHX9	IMP		Human	PMID:17531811
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	DHX9	IMP		Human	PMID:15355351
Biological Process	GO:1905698	positive regulation of polysome binding	DHX9	IMP		Human	PMID:22190748
Biological Process	GO:0060760	positive regulation of response to cytokine stimulus	DHX9	IMP		Human	PMID:21957149
Biological Process	GO:0046833	positive regulation of RNA export from nucleus	DHX9	IDA		Human	PMID:11402034
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	DHX9	IMP		Human	PMID:11038348
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	DHX9	IMP		Human	PMID:11416126
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	DHX9	IMP		Human	PMID:21957149
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	DHX9	IMP		Human	PMID:9323138
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	DHX9	IMP		Human	PMID:20696886
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	DHX9	IMP		Human	PMID:21957149
Biological Process	GO:0050434	positive regulation of viral transcription	DHX9	IDA		Human	PMID:11096080
Biological Process	GO:1904973	positive regulation of viral translation	DHX9	IMP		Human	PMID:16680162
Biological Process	GO:1903608	protein localization to cytoplasmic stress granule	DHX9	IMP		Human	PMID:24965446
Biological Process	GO:0065003	protein-containing complex assembly	DHX9	IDA		Human	PMID:23361462
Biological Process	GO:0070269	pyroptosis	Dhx9	IMP		Mouse	MGI:MGI:5908739|PMID:28636595
Biological Process	GO:2000765	regulation of cytoplasmic translation	DHX9	IDA		Human	PMID:28355180
Biological Process	GO:0050691	regulation of defense response to virus by host	Dhx9	IMP		Mouse	MGI:MGI:5908739|PMID:28636595
Biological Process	GO:0050684	regulation of mRNA processing	DHX9	IDA		Human	PMID:28355180
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	DHX9	IMP		Human	PMID:9662397
Biological Process	GO:0009615	response to virus	dhx9	IMP	ZFIN:ZDB-MRPHLNO-171109-4	Zfish	PMID:25972544
Biological Process	GO:0009615	response to virus	dhx9	IGI	ZFIN:ZDB-GENE-030131-1927	Zfish	PMID:25972544
Biological Process	GO:0070922	RISC complex assembly	DHX9	IMP		Human	PMID:17531811
Biological Process	GO:0010501	RNA secondary structure unwinding	DHX9	IDA		Human	PMID:1537828
Biological Process	GO:0010501	RNA secondary structure unwinding	DHX9	IDA		Human	PMID:9111062

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern