Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DIAPH1
  • Mouse genes Diaph1
  • Rat genes Diaph1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Diaph1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Diaph1	IDA		Mouse	PMID:14992721
Molecular Function	GO:0042802	identical protein binding	Diaph1	IPI	UniProtKB:O08808	Mouse	MGI:MGI:5447632|PMID:10559899
Molecular Function	GO:0042802	identical protein binding	Diaph1	IPI	UniProtKB:O08808	Mouse	MGI:MGI:2670483|PMID:12906795
Molecular Function	GO:0042802	identical protein binding	Diaph1	IPI	UniProtKB:O08808	Mouse	MGI:MGI:5927317|PMID:16472745
Molecular Function	GO:0005522	profilin binding	Diaph1	IDA		Mouse	PMID:9214622
Molecular Function	GO:0005515	protein binding	DIAPH1	IPI	UniProtKB:P61586	Human	PMID:18218625
Molecular Function	GO:0005515	protein binding	DIAPH1	IPI	UniProtKB:P49593	Human	PMID:18230650
Molecular Function	GO:0005515	protein binding	DIAPH1	IPI	UniProtKB:Q15109	Human	PMID:18922799
Molecular Function	GO:0005515	protein binding	DIAPH1	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	Diaph1	IPI	UniProtKB:Q9Z0E0	Mouse	MGI:MGI:3807403|PMID:18572016
Molecular Function	GO:0005515	protein binding	Diaph1	IPI	UniProtKB:Q8BKX1	Mouse	MGI:MGI:1858529|PMID:10814512
Molecular Function	GO:0005515	protein binding	Diaph1	IPI	UniProtKB:P46940	Mouse	MGI:MGI:5486552|PMID:17620407
Molecular Function	GO:0005515	protein binding	Diaph1	IPI	UniProtKB:Q8C8N2	Mouse	MGI:MGI:3850304|PMID:19350017
Molecular Function	GO:0005515	protein binding	Diaph1	IPI	PR:B8QI33	Mouse	PMID:22266902
Molecular Function	GO:0005515	protein binding	Diaph1	IPI	PR:Q9QUI0	Mouse	PMID:9214622
Molecular Function	GO:0003723	RNA binding	DIAPH1	HDA		Human	PMID:22658674
Molecular Function	GO:0031267	small GTPase binding	Diaph1	IDA		Mouse	PMID:9214622
Molecular Function	GO:0044325	transmembrane transporter binding	DIAPH1	IPI	UniProtKB:Q13563	Human	PMID:15123714
Molecular Function	GO:0044325	transmembrane transporter binding	Diaph1	IPI	UniProtKB:Q13563	Mouse	MGI:MGI:5315358|PMID:15123714
Cellular Component	GO:0005903	brush border	Diaph1	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0005737	cytoplasm	Diaph1	IDA		Mouse	MGI:MGI:6201827|PMID:23558171
Cellular Component	GO:0072686	mitotic spindle	DIAPH1	IDA		Human	PMID:15123714
Cellular Component	GO:0043005	neuron projection	Diaph1	IDA		Mouse	MGI:MGI:3807403|PMID:18572016
Cellular Component	GO:0005634	nucleus	Diaph1	IDA		Mouse	MGI:MGI:6201827|PMID:23558171
Cellular Component	GO:0098793	presynapse	Diaph1	IMP		Mouse	MGI:MGI:6114312|PMID:28231467
Cellular Component	GO:0032587	ruffle membrane	Diaph1	IDA		Mouse	PMID:9214622
Cellular Component	GO:0045202	synapse	Diaph1	IMP		Mouse	MGI:MGI:6114312|PMID:28231467
Biological Process	GO:0030036	actin cytoskeleton organization	Diaph1	IDA		Mouse	MGI:MGI:6201827|PMID:23558171
Biological Process	GO:0030036	actin cytoskeleton organization	Diaph1	IDA		Mouse	PMID:9214622
Biological Process	GO:0030041	actin filament polymerization	Diaph1	IDA		Mouse	MGI:MGI:6201827|PMID:23558171
Biological Process	GO:0030041	actin filament polymerization	Diaph1	IDA		Mouse	PMID:14992721
Biological Process	GO:0007420	brain development	Diaph1	IMP		Mouse	MGI:MGI:5707577|PMID:24781755
Biological Process	GO:0071420	cellular response to histamine	DIAPH1	IMP		Human	PMID:15123714
Biological Process	GO:0007010	cytoskeleton organization	DIAPH1	IMP		Human	PMID:21834987
Biological Process	GO:0007010	cytoskeleton organization	Diaph1	IDA		Mouse	MGI:MGI:6201827|PMID:23558171
Biological Process	GO:0031175	neuron projection development	Diaph1	IDA		Mouse	MGI:MGI:3807403|PMID:18572016
Biological Process	GO:0030335	positive regulation of cell migration	Diaph1	IMP		Rat	PMID:16943426|RGD:1601059
Biological Process	GO:0035372	protein localization to microtubule	DIAPH1	IMP		Human	PMID:15123714
Biological Process	GO:0008360	regulation of cell shape	DIAPH1	IMP		Human	PMID:21834987
Biological Process	GO:0051493	regulation of cytoskeleton organization	DIAPH1	IMP		Human	PMID:26912466
Biological Process	GO:0032886	regulation of microtubule-based process	DIAPH1	IMP		Human	PMID:20937854
Biological Process	GO:0051279	regulation of release of sequestered calcium ion into cytosol	DIAPH1	IMP		Human	PMID:15123714
Biological Process	GO:0048488	synaptic vesicle endocytosis	Diaph1	IMP		Mouse	PMID:28231467
Biological Process	GO:0048488	synaptic vesicle endocytosis	Diaph1	IDA		Mouse	PMID:28231467

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern