Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DIXDC1
  • Mouse genes Dixdc1
  • Rat genes Dixdc1
  • Zfish genes dixdc1a,dixdc1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dixdc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043015	gamma-tubulin binding	DIXDC1	IDA		Human	PMID:19375513
Molecular Function	GO:0042802	identical protein binding	dixdc1a	IPI	ZFIN:ZDB-GENE-030721-2	Zfish	PMID:28798413
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	Dixdc1	IDA		Rat	PMID:19339625|RGD:2308917
Molecular Function	GO:0005515	protein binding	DIXDC1	IPI	UniProtKB:O14641	Human	PMID:20823832
Molecular Function	GO:0005515	protein binding	DIXDC1	IPI	UniProtKB:Q60838	Human	PMID:21189423
Molecular Function	GO:0005515	protein binding	Dixdc1	IPI	UniProtKB:Q811T9	Mouse	MGI:MGI:4821185|PMID:20624590
Molecular Function	GO:0005515	protein binding	Dixdc1	IPI	UniProtKB:Q9ERR1	Mouse	MGI:MGI:4821185|PMID:20624590
Molecular Function	GO:0005515	protein binding	Dixdc1	IPI	UniProtKB:P51141	Mouse	PMID:21189423
Molecular Function	GO:0019904	protein domain specific binding	Dixdc1	IPI	PR:O35625	Mouse	PMID:15579909
Cellular Component	GO:0043679	axon terminus	Dixdc1	IDA		Rat	PMID:19339625|RGD:2308917
Cellular Component	GO:0005737	cytoplasm	Dixdc1	IDA		Rat	PMID:19339625|RGD:2308917
Cellular Component	GO:0005829	cytosol	DIXDC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	DIXDC1	IDA		Human	PMID:19375513
Cellular Component	GO:0005829	cytosol	Dixdc1	IDA		Mouse	PMID:21189423
Cellular Component	GO:0043025	neuronal cell body	Dixdc1	IDA		Rat	PMID:19339625|RGD:2308917
Cellular Component	GO:0032991	protein-containing complex	Dixdc1	IDA		Rat	PMID:19339625|RGD:2308917
Biological Process	GO:0043010	camera-type eye development	dixdc1a	IMP		Zfish	PMID:12526749
Biological Process	GO:0060070	canonical Wnt signaling pathway	DIXDC1	IDA		Human	PMID:21189423
Biological Process	GO:0060070	canonical Wnt signaling pathway	Dixdc1	IMP		Mouse	MGI:MGI:4821185|PMID:20624590
Biological Process	GO:0060070	canonical Wnt signaling pathway	dixdc1a	IDA		Zfish	PMID:12526749
Biological Process	GO:0060070	canonical Wnt signaling pathway	dixdc1a	IDA		Zfish	PMID:15857680
Biological Process	GO:0021846	cell proliferation in forebrain	Dixdc1	IMP		Mouse	MGI:MGI:4821185|PMID:20624590
Biological Process	GO:0021695	cerebellar cortex development	Dixdc1	IMP		Rat	PMID:19339625|RGD:2308917
Biological Process	GO:0021795	cerebral cortex cell migration	Dixdc1	IMP		Mouse	MGI:MGI:4821185|PMID:20624590
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	Dixdc1	IMP		Mouse	MGI:MGI:4821185|PMID:20624590
Biological Process	GO:0030900	forebrain development	dixdc1a	IMP		Zfish	PMID:12526749
Biological Process	GO:0021869	forebrain ventricular zone progenitor cell division	Dixdc1	IMP		Mouse	MGI:MGI:4821185|PMID:20624590
Biological Process	GO:0045665	negative regulation of neuron differentiation	Dixdc1	IMP		Mouse	MGI:MGI:4821185|PMID:20624590
Biological Process	GO:0050772	positive regulation of axonogenesis	Dixdc1	IMP		Rat	PMID:19339625|RGD:2308917
Biological Process	GO:0046330	positive regulation of JNK cascade	Dixdc1	IMP		Rat	PMID:19339625|RGD:2308917
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	Dixdc1	IMP		Mouse	MGI:MGI:4821185|PMID:20624590
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Dixdc1	IMP		Mouse	MGI:MGI:4821185|PMID:20624590
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	Dixdc1	IMP		Mouse	MGI:MGI:4821185|PMID:20624590

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern