Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DKKL1
  • Mouse genes Dkkl1
  • Rat genes Dkkl1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dkkl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Dkkl1	IPI	MGI:MGI:1922390	Mouse	PMID:21698294
Molecular Function	GO:0005515	protein binding	Dkkl1	IPI	UniProtKB:Q810R0	Mouse	PMID:19176879
Cellular Component	GO:0001669	acrosomal vesicle	Dkkl1	IDA		Mouse	MGI:MGI:4360455|PMID:19176879
Cellular Component	GO:0001669	acrosomal vesicle	Dkkl1	IDA		Mouse	MGI:MGI:3582143|PMID:15892050
Biological Process	GO:0060070	canonical Wnt signaling pathway	Dkkl1	IDA		Mouse	PMID:29715368
Biological Process	GO:2000225	negative regulation of testosterone biosynthetic process	Dkkl1	IMP		Mouse	MGI:MGI:3839065|PMID:18818293
Biological Process	GO:0007341	penetration of zona pellucida	Dkkl1	IMP		Mouse	MGI:MGI:4438468|PMID:19596312
Biological Process	GO:0043065	positive regulation of apoptotic process	Dkkl1	IMP		Mouse	MGI:MGI:3839065|PMID:18818293
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Dkkl1	IDA		Mouse	PMID:12055200

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern