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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Dll3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dll3
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0042802identical protein bindingdlcIDAZfishPMID:18296487
Molecular FunctionGO:0005112Notch bindingDll3IPIRGD:737367RatPMID:16144902|RGD:1599776
Molecular FunctionGO:0030165PDZ domain bindingdlcIPIUniProtKB:Q5WPB2ZfishPMID:15509766
Molecular FunctionGO:0030165PDZ domain bindingdlcIDAZfishPMID:15509766
Molecular FunctionGO:0005515protein bindingDll3IPIPR:O35516MousePMID:34635817
Molecular FunctionGO:0005515protein bindingDll3IPIPR:A2AFI6MousePMID:34635817
Molecular FunctionGO:0005515protein bindingDll3IPIPR:Q80SY4MousePMID:16000382
Cellular ComponentGO:0005737cytoplasmdlcIDAZfishPMID:19056830
Cellular ComponentGO:0048471perinuclear region of cytoplasmdlcIGIZFIN:ZDB-GENE-050628-1ZfishPMID:17196985
Cellular ComponentGO:0048471perinuclear region of cytoplasmdlcIGIZFIN:ZDB-GENE-030404-2ZfishPMID:17196985
Cellular ComponentGO:0005886plasma membraneDll3IDAMousePMID:34635817
Cellular ComponentGO:0005886plasma membranedlcIDAZfishPMID:17196985
Biological ProcessGO:0060842arterial endothelial cell differentiationdlcIMPZFIN:ZDB-MRPHLNO-050531-2ZfishPMID:24598161
Biological ProcessGO:0048514blood vessel morphogenesisdlcIMPZFIN:ZDB-GENO-130820-155ZfishPMID:16607654
Biological ProcessGO:0048514blood vessel morphogenesisdlcIMPZFIN:ZDB-MRPHLNO-060712-1ZfishPMID:16607654
Biological ProcessGO:0048514blood vessel morphogenesisdlcIMPZFIN:ZDB-GENO-130820-153ZfishPMID:16607654
Biological ProcessGO:0048514blood vessel morphogenesisdlcIMPZFIN:ZDB-MRPHLNO-060712-2ZfishPMID:16607654
Biological ProcessGO:0007417central nervous system developmentDll3IEPRatPMID:14743446|RGD:1304491
Biological ProcessGO:0007386compartment pattern specificationDll3IMPMGI:MGI:1857008MousePMID:12001066
Biological ProcessGO:0021536diencephalon developmentdlbIGIZFIN:ZDB-GENO-120731-2ZfishPMID:21148001
Biological ProcessGO:0021536diencephalon developmentdlbIMPZFIN:ZDB-GENO-080605-3ZfishPMID:21148001
Biological ProcessGO:0021536diencephalon developmentdlbIGIZFIN:ZDB-GENO-120731-3ZfishPMID:21148001
Biological ProcessGO:0021536diencephalon developmentdlbIGIZFIN:ZDB-GENO-120731-4ZfishPMID:21148001
Biological ProcessGO:0035907dorsal aorta developmentdlcIGIZFIN:ZDB-GENO-101105-1,ZFIN:ZDB-MRPHLNO-070509-2ZfishPMID:24598161
Biological ProcessGO:0002244hematopoietic progenitor cell differentiationdlcIMPZfishZFIN:ZDB-PUB-170214-264
Biological ProcessGO:0002244hematopoietic progenitor cell differentiationdlcIGIZFIN:ZDB-GENO-100412-15,ZFIN:ZDB-MRPHLNO-070614-5ZfishPMID:25230933
Biological ProcessGO:0060218hematopoietic stem cell differentiationdlcIMPZFIN:ZDB-GENO-101105-1ZfishPMID:21654806
Biological ProcessGO:0060218hematopoietic stem cell differentiationdlcIGIZFIN:ZDB-GENO-101105-1,ZFIN:ZDB-MRPHLNO-081030-1ZfishPMID:21654806
Biological ProcessGO:0030901midbrain developmentdlbIGIZFIN:ZDB-GENO-120731-2ZfishPMID:21148001
Biological ProcessGO:0048712negative regulation of astrocyte differentiationDll3IDARatPMID:16144902|RGD:1599776
Biological ProcessGO:0050768negative regulation of neurogenesisDll3IDAMousePMID:9272948
Biological ProcessGO:0045746negative regulation of Notch signaling pathwayDll3IDARatPMID:16144902|RGD:1599776
Biological ProcessGO:0048666neuron developmentdlcIMPZFIN:ZDB-GENO-980202-1156ZfishPMID:16125692
Biological ProcessGO:0048666neuron developmentdlcIMPZFIN:ZDB-GENO-980202-1157ZfishPMID:16125692
Biological ProcessGO:0048666neuron developmentdlcIMPZFIN:ZDB-GENO-070123-4ZfishPMID:16125692
Biological ProcessGO:0048666neuron developmentdlcIMPZFIN:ZDB-GENO-050621-3ZfishPMID:16125692
Biological ProcessGO:0048666neuron developmentdlcIMPZFIN:ZDB-GENO-051114-1ZfishPMID:16125692
Biological ProcessGO:0007219Notch signaling pathwaydlcIMPZFIN:ZDB-GENO-101105-1ZfishPMID:21654806
Biological ProcessGO:0048339paraxial mesoderm developmentDll3IMPMGI:MGI:1857008MousePMID:15170697
Biological ProcessGO:0050769positive regulation of neurogenesisDll3IDARatPMID:16144902|RGD:1599776
Biological ProcessGO:0061056sclerotome developmentdlcIGIZFIN:ZDB-GENO-100412-15,ZFIN:ZDB-MRPHLNO-070614-5ZfishPMID:25230933
Biological ProcessGO:0001501skeletal system developmentDLL3IMPHumanPMID:10742114
Biological ProcessGO:0001501skeletal system developmentDll3IMPMouseMGI:MGI:2178102|PMID:11923214
Biological ProcessGO:0001757somite specificationdlcIGIZFIN:ZDB-GENO-120725-3ZfishPMID:22723933
Biological ProcessGO:0001756somitogenesisDll3IDAMousePMID:9272948
Biological ProcessGO:0001756somitogenesisDll3IMPMGI:MGI:1857008MousePMID:15170697
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-050621-3ZfishPMID:16125692
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-980202-1157ZfishPMID:16125692
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-051114-1ZfishPMID:16125692
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-980202-1156ZfishPMID:9706695
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-070123-4ZfishPMID:16125692
Biological ProcessGO:0001756somitogenesisdlcIGIZFIN:ZDB-GENO-070123-4,ZFIN:ZDB-MRPHLNO-050531-3,ZFIN:ZDB-MRPHLNO-050531-4ZfishPMID:15766754
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-980202-1156ZfishPMID:9007237
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-130820-155ZfishPMID:16607654
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-100823-1ZfishPMID:29624170
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-070123-4ZfishPMID:16545363
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-070123-4ZfishPMID:9007237
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-980202-1156ZfishPMID:16125692
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-980202-1157ZfishPMID:9007237
Biological ProcessGO:0001756somitogenesisdlcIEPZfishPMID:16760970
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-110812-5ZfishPMID:24715465
Biological ProcessGO:0001756somitogenesisdlcIGIZFIN:ZDB-MRPHLNO-050526-1,ZFIN:ZDB-MRPHLNO-050526-2,ZFIN:ZDB-MRPHLNO-050531-3,ZFIN:ZDB-MRPHLNO-050531-4ZfishPMID:15766754
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-MRPHLNO-050531-3,ZFIN:ZDB-MRPHLNO-050531-4ZfishPMID:15766754
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-051214-4ZfishPMID:16225858
Biological ProcessGO:0001756somitogenesisdlcIMPZFIN:ZDB-GENO-130820-153ZfishPMID:16607654
Biological ProcessGO:0009888tissue developmentDll3IDAMousePMID:9272948
Biological ProcessGO:0021514ventral spinal cord interneuron differentiationdlcIGIZFIN:ZDB-GENE-980526-29ZfishPMID:24768892
Biological ProcessGO:0021514ventral spinal cord interneuron differentiationdlcIGIZFIN:ZDB-GENE-980526-29,ZFIN:ZDB-GENE-990415-47ZfishPMID:24768892

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory