Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DMBX1
  • Mouse genes Dmbx1
  • Rat genes Dmbx1
  • Zfish genes dmbx1a,dmbx1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dmbx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Dmbx1	IDA		Mouse	MGI:MGI:2183620|PMID:12055180
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Dmbx1	IDA		Mouse	MGI:MGI:2183620|PMID:12055180
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Dmbx1	IDA		Mouse	MGI:MGI:3583840|PMID:15890343
Molecular Function	GO:0042802	identical protein binding	Dmbx1	IPI	PR:Q91ZK4	Mouse	PMID:15890343
Molecular Function	GO:0005515	protein binding	Dmbx1	IPI	PR:P80206	Mouse	PMID:15890343
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Dmbx1	IDA		Mouse	MGI:MGI:3583840|PMID:15890343
Molecular Function	GO:0043565	sequence-specific DNA binding	Dmbx1	IDA		Mouse	MGI:MGI:3583840|PMID:15890343
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	DMBX1	IDA		Human	PMID:28473536
Cellular Component	GO:0005667	transcription regulator complex	Dmbx1	IDA		Mouse	PMID:15890343
Biological Process	GO:0008343	adult feeding behavior	Dmbx1	IGI	MGI:MGI:87853	Mouse	PMID:17873059
Biological Process	GO:0008343	adult feeding behavior	Dmbx1	IMP	MGI:MGI:3759315	Mouse	PMID:17873059
Biological Process	GO:0008343	adult feeding behavior	Dmbx1	IGI	MGI:MGI:892013	Mouse	PMID:17873059
Biological Process	GO:0008344	adult locomotory behavior	Dmbx1	IMP	MGI:MGI:3759315	Mouse	PMID:17873059
Biological Process	GO:0007420	brain development	Dmbx1	IEP		Mouse	MGI:MGI:3054504|PMID:15314164
Biological Process	GO:0007420	brain development	dmbx1a	IEP		Zfish	PMID:12142024|ZFIN:ZDB-PUB-020807-10
Biological Process	GO:0043010	camera-type eye development	dmbx1a	IMP	ZFIN:ZDB-MRPHLNO-100412-1	Zfish	PMID:12142024
Biological Process	GO:0043010	camera-type eye development	dmbx1a	IMP	ZFIN:ZDB-MRPHLNO-100412-1,ZFIN:ZDB-MRPHLNO-100412-2	Zfish	PMID:12142024
Biological Process	GO:0007417	central nervous system development	Dmbx1	IEP		Mouse	MGI:MGI:2183620|PMID:12055180
Biological Process	GO:0048589	developmental growth	Dmbx1	IEP		Mouse	MGI:MGI:3054504|PMID:15314164
Biological Process	GO:0001654	eye development	dmbx1a	IEP		Zfish	PMID:12142024|ZFIN:ZDB-PUB-020807-10
Biological Process	GO:0030901	midbrain development	dmbx1a	IMP	ZFIN:ZDB-MRPHLNO-100412-1	Zfish	PMID:12142024
Biological Process	GO:0030901	midbrain development	dmbx1a	IMP	ZFIN:ZDB-MRPHLNO-100412-1	Zfish	PMID:20860823
Biological Process	GO:0030901	midbrain development	dmbx1b	IMP	ZFIN:ZDB-MRPHLNO-101027-2	Zfish	PMID:20860823
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Dmbx1	IDA		Mouse	MGI:MGI:3583840|PMID:15890343
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Dmbx1	IDA		Mouse	MGI:MGI:2183620|PMID:12055180
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	dmbx1a	IMP		Zfish	PMID:12142024|ZFIN:ZDB-PUB-020807-10
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Dmbx1	IDA		Mouse	MGI:MGI:3583840|PMID:15890343
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Dmbx1	IGI	MGI:MGI:97451	Mouse	PMID:15890343
Biological Process	GO:0051726	regulation of cell cycle	dmbx1a	IMP	ZFIN:ZDB-MRPHLNO-100412-1	Zfish	PMID:20860823
Biological Process	GO:0051726	regulation of cell cycle	dmbx1b	IMP	ZFIN:ZDB-MRPHLNO-101027-2	Zfish	PMID:20860823
Biological Process	GO:0007346	regulation of mitotic cell cycle	dmbx1a	IGI	ZFIN:ZDB-GENE-050417-97	Zfish	PMID:25872183
Biological Process	GO:0007346	regulation of mitotic cell cycle	dmbx1b	IGI	ZFIN:ZDB-GENE-020117-1	Zfish	PMID:25872183
Biological Process	GO:0061074	regulation of neural retina development	dmbx1a	IGI	ZFIN:ZDB-GENE-001222-1,ZFIN:ZDB-GENE-050417-97	Zfish	PMID:25872183
Biological Process	GO:0061074	regulation of neural retina development	dmbx1a	IGI	ZFIN:ZDB-GENE-050417-97	Zfish	PMID:25872183
Biological Process	GO:0061074	regulation of neural retina development	dmbx1a	IGI	ZFIN:ZDB-GENE-050417-97,ZFIN:ZDB-GENE-980526-176	Zfish	PMID:25872183
Biological Process	GO:0061074	regulation of neural retina development	dmbx1b	IGI	ZFIN:ZDB-GENE-020117-1,ZFIN:ZDB-GENE-980526-176	Zfish	PMID:25872183
Biological Process	GO:0061074	regulation of neural retina development	dmbx1b	IGI	ZFIN:ZDB-GENE-001222-1,ZFIN:ZDB-GENE-020117-1	Zfish	PMID:25872183
Biological Process	GO:0061074	regulation of neural retina development	dmbx1b	IGI	ZFIN:ZDB-GENE-020117-1	Zfish	PMID:25872183
Biological Process	GO:0050767	regulation of neurogenesis	dmbx1a	IMP	ZFIN:ZDB-MRPHLNO-100412-1	Zfish	PMID:20860823
Biological Process	GO:0050767	regulation of neurogenesis	dmbx1a	IGI	ZFIN:ZDB-MRPHLNO-100412-1,ZFIN:ZDB-MRPHLNO-101027-2	Zfish	PMID:20860823
Biological Process	GO:0050767	regulation of neurogenesis	dmbx1b	IGI	ZFIN:ZDB-MRPHLNO-100412-1,ZFIN:ZDB-MRPHLNO-101027-2	Zfish	PMID:20860823
Biological Process	GO:0050767	regulation of neurogenesis	dmbx1b	IMP	ZFIN:ZDB-MRPHLNO-101027-2	Zfish	PMID:20860823
Biological Process	GO:0060041	retina development in camera-type eye	dmbx1a	IMP	ZFIN:ZDB-MRPHLNO-100412-1	Zfish	PMID:20860823
Biological Process	GO:0060041	retina development in camera-type eye	dmbx1b	IMP	ZFIN:ZDB-MRPHLNO-101027-2	Zfish	PMID:20860823

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern