Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DMC1
  • Mouse genes Dmc1
  • Rat genes Dmc1
  • Zfish genes dmc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dmc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	DMC1	IDA		Human	PMID:15899844
Molecular Function	GO:0000150	DNA strand exchange activity	Dmc1	IDA		Mouse	PMID:17639081
Molecular Function	GO:0042802	identical protein binding	DMC1	IPI	UniProtKB:Q14565	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	DMC1	IPI	UniProtKB:Q14565	Human	PMID:25502805
Molecular Function	GO:0042802	identical protein binding	DMC1	IPI	UniProtKB:Q14565	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:P51587	Human	PMID:17541404
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q96B01	Human	PMID:17996711
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:P51587	Human	PMID:20729832
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q96B01-2	Human	PMID:21307306
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q96B01-2	Human	PMID:21903585
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:P25788	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:P36406	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q8N5Z5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q9GZT8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q9H8Y8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:O00560	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:P25788	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q9GZT8	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:O00560	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:P25788	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q8N5Z5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q9H8Y8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q9GZT8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q9H190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q9H8Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DMC1	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Cellular Component	GO:0005694	chromosome	Dmc1	IDA		Mouse	MGI:MGI:6478065|PMID:30746471
Cellular Component	GO:0005694	chromosome	Dmc1	IDA		Mouse	MGI:MGI:6443349|PMID:32463460
Cellular Component	GO:0005694	chromosome	Dmc1	IDA		Mouse	MGI:MGI:5319701|PMID:22549958
Cellular Component	GO:0005694	chromosome	Dmc1	IDA		Mouse	MGI:MGI:6400008|PMID:30949703
Cellular Component	GO:0005694	chromosome	Dmc1	IDA		Mouse	MGI:MGI:6283956|PMID:30760716
Cellular Component	GO:0005694	chromosome	Dmc1	IDA		Mouse	MGI:MGI:4946339|PMID:21307306
Cellular Component	GO:0000781	chromosome, telomeric region	Dmc1	IDA		Mouse	PMID:20336070
Cellular Component	GO:0000794	condensed nuclear chromosome	Dmc1	IDA		Mouse	PMID:20551173
Cellular Component	GO:0000794	condensed nuclear chromosome	Dmc1	IDA		Mouse	PMID:27760146
Cellular Component	GO:0000794	condensed nuclear chromosome	Dmc1	IDA		Mouse	PMID:18283110
Cellular Component	GO:0000794	condensed nuclear chromosome	Dmc1	IDA		Mouse	PMID:22530760
Cellular Component	GO:0000794	condensed nuclear chromosome	Dmc1	IDA		Mouse	PMID:22164254
Cellular Component	GO:0000794	condensed nuclear chromosome	Dmc1	IDA		Mouse	PMID:18316482
Cellular Component	GO:0000794	condensed nuclear chromosome	Dmc1	IDA		Mouse	PMID:22711701
Cellular Component	GO:0000800	lateral element	Dmc1	IDA		Mouse	PMID:30718482
Cellular Component	GO:0005634	nucleus	DMC1	IDA		Human	PMID:22899867
Cellular Component	GO:0005634	nucleus	Dmc1	IDA		Mouse	MGI:MGI:4946339|PMID:21307306
Cellular Component	GO:0005634	nucleus	Dmc1	IDA		Mouse	PMID:22190708
Cellular Component	GO:0035861	site of double-strand break	Dmc1	IDA		Mouse	PMID:32463460
Cellular Component	GO:0035861	site of double-strand break	Dmc1	IDA		Mouse	PMID:30760716
Biological Process	GO:1990918	double-strand break repair involved in meiotic recombination	Dmc1	IDA		Mouse	PMID:17639081
Biological Process	GO:0000724	double-strand break repair via homologous recombination	Dmc1	IDA		Mouse	PMID:17639081
Biological Process	GO:0007276	gamete generation	Dmc1	IMP	MGI:MGI:2177010	Mouse	PMID:12855593
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	Dmc1	IMP	MGI:MGI:2176331	Mouse	PMID:17696610
Biological Process	GO:0007141	male meiosis I	Dmc1	IDA		Mouse	PMID:17639081
Biological Process	GO:0007141	male meiosis I	Dmc1	IMP	MGI:MGI:2176331	Mouse	PMID:17696610
Biological Process	GO:0001556	oocyte maturation	Dmc1	IMP	MGI:MGI:2176331	Mouse	PMID:17696610
Biological Process	GO:0048477	oogenesis	Dmc1	IGI	MGI:MGI:3028590	Mouse	PMID:15928951
Biological Process	GO:0048477	oogenesis	Dmc1	IMP	MGI:MGI:2176331	Mouse	PMID:15928951
Biological Process	GO:0001541	ovarian follicle development	Dmc1	IMP	MGI:MGI:2176331	Mouse	PMID:15640358
Biological Process	GO:0007131	reciprocal meiotic recombination	DMC1	IDA		Human	PMID:21307306
Biological Process	GO:0007286	spermatid development	Dmc1	IMP	MGI:MGI:2176331	Mouse	PMID:17696610
Biological Process	GO:0007283	spermatogenesis	Dmc1	IMP	MGI:MGI:2177010	Mouse	PMID:12855593
Biological Process	GO:0007283	spermatogenesis	Dmc1	IMP	MGI:MGI:2176331	Mouse	PMID:15928951
Biological Process	GO:0007283	spermatogenesis	Dmc1	IGI	MGI:MGI:3028590	Mouse	PMID:15928951

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern