Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DMRT1
  • Mouse genes Dmrt1
  • Rat genes Dmrt1
  • Zfish genes dmrt1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dmrt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Dmrt1	IDA		Mouse	PMID:23473982
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Dmrt1	IDA		Mouse	MGI:MGI:4818833|PMID:20616082
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Dmrt1	IDA		Mouse	MGI:MGI:4839662|PMID:20951351
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Dmrt1	IDA		Mouse	MGI:MGI:5474771|PMID:17605809
Molecular Function	GO:0042802	identical protein binding	DMRT1	IPI	UniProtKB:Q9Y5R6	Human	PMID:26005864
Molecular Function	GO:0042802	identical protein binding	Dmrt1	IPI	PR:Q9QZ59	Mouse	PMID:17605809
Molecular Function	GO:0005515	protein binding	Dmrt1	IPI	PR:A2A9A2	Mouse	PMID:17605809
Molecular Function	GO:0005515	protein binding	Dmrt1	IPI	PR:Q80WT2	Mouse	PMID:17605809
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Dmrt1	IDA		Mouse	MGI:MGI:5474771|PMID:17605809
Molecular Function	GO:0043565	sequence-specific DNA binding	Dmrt1	IDA		Mouse	PMID:17605809
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	DMRT1	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Dmrt1	IDA		Mouse	PMID:21621532
Cellular Component	GO:0001674	female germ cell nucleus	Dmrt1	IDA		Mouse	PMID:21621532
Cellular Component	GO:0005634	nucleus	DMRT1	IDA		Human	PMID:22899867
Cellular Component	GO:0005634	nucleus	Dmrt1	IDA		Mouse	MGI:MGI:1926717|PMID:11040213
Biological Process	GO:0000902	cell morphogenesis	Dmrt1	IMP	MGI:MGI:2385911	Mouse	PMID:17540358
Biological Process	GO:0000902	cell morphogenesis	Dmrt1	IMP	MGI:MGI:2385912	Mouse	PMID:17540358
Biological Process	GO:0003006	developmental process involved in reproduction	Dmrt1	IGI	MGI:MGI:87983	Mouse	PMID:17540358
Biological Process	GO:0007281	germ cell development	dmrt1	IMP	ZFIN:ZDB-GENO-180831-4	Zfish	PMID:28893856
Biological Process	GO:0007281	germ cell development	dmrt1	IMP	ZFIN:ZDB-GENO-180831-5	Zfish	PMID:28893856
Biological Process	GO:0008354	germ cell migration	Dmrt1	IMP	MGI:MGI:2385911	Mouse	PMID:17540358
Biological Process	GO:0008354	germ cell migration	Dmrt1	IMP	MGI:MGI:2385912	Mouse	PMID:17540358
Biological Process	GO:0035556	intracellular signal transduction	Dmrt1	IDA		Rat	PMID:11181532|RGD:628438
Biological Process	GO:0002176	male germ cell proliferation	Dmrt1	IMP		Mouse	MGI:MGI:4839662|PMID:20951351
Biological Process	GO:0002176	male germ cell proliferation	Dmrt1	IMP		Mouse	MGI:MGI:4420727|PMID:20007774
Biological Process	GO:0002176	male germ cell proliferation	dmrt1	IMP	ZFIN:ZDB-GENO-180831-4	Zfish	PMID:28893856
Biological Process	GO:0002176	male germ cell proliferation	dmrt1	IMP	ZFIN:ZDB-GENO-180831-5	Zfish	PMID:28893856
Biological Process	GO:0008584	male gonad development	Dmrt1	IMP	MGI:MGI:2385911	Mouse	PMID:17540358
Biological Process	GO:0008584	male gonad development	Dmrt1	IMP	MGI:MGI:2385911	Mouse	PMID:21775990
Biological Process	GO:0008584	male gonad development	Dmrt1	IMP	MGI:MGI:2385912	Mouse	PMID:17540358
Biological Process	GO:0008584	male gonad development	dmrt1	IMP	ZFIN:ZDB-GENO-210104-5	Zfish	PMID:32001440
Biological Process	GO:0008584	male gonad development	dmrt1	IMP	ZFIN:ZDB-GENO-180831-5	Zfish	PMID:28893856
Biological Process	GO:0008584	male gonad development	dmrt1	IMP	ZFIN:ZDB-GENO-170321-7	Zfish	PMID:27940159
Biological Process	GO:0008584	male gonad development	dmrt1	IMP	ZFIN:ZDB-GENO-170321-4	Zfish	PMID:27940159
Biological Process	GO:0008584	male gonad development	dmrt1	IMP	ZFIN:ZDB-GENO-170321-5	Zfish	PMID:27940159
Biological Process	GO:0008584	male gonad development	dmrt1	IMP	ZFIN:ZDB-GENO-170321-22	Zfish	PMID:27940159
Biological Process	GO:0008584	male gonad development	dmrt1	IMP	ZFIN:ZDB-GENO-180831-4	Zfish	PMID:28893856
Biological Process	GO:0008584	male gonad development	dmrt1	IMP	ZFIN:ZDB-GENO-170321-6	Zfish	PMID:27940159
Biological Process	GO:0030238	male sex determination	Dmrt1	IMP		Mouse	MGI:MGI:1926717|PMID:11040213
Biological Process	GO:0030238	male sex determination	Dmrt1	IMP		Mouse	MGI:MGI:4420727|PMID:20007774
Biological Process	GO:0030238	male sex determination	Dmrt1	IMP		Mouse	MGI:MGI:4839662|PMID:20951351
Biological Process	GO:0030238	male sex determination	dmrt1	IMP	ZFIN:ZDB-GENO-170321-5	Zfish	PMID:27940159
Biological Process	GO:0030238	male sex determination	dmrt1	IMP	ZFIN:ZDB-GENO-170321-4	Zfish	PMID:27940159
Biological Process	GO:0030238	male sex determination	dmrt1	IMP	ZFIN:ZDB-GENO-170321-7	Zfish	PMID:27940159
Biological Process	GO:0030238	male sex determination	dmrt1	IMP	ZFIN:ZDB-GENO-170321-6	Zfish	PMID:27940159
Biological Process	GO:0046661	male sex differentiation	Dmrt1	IMP		Mouse	MGI:MGI:4420727|PMID:20007774
Biological Process	GO:0046661	male sex differentiation	Dmrt1	IMP		Mouse	MGI:MGI:1926717|PMID:11040213
Biological Process	GO:0046661	male sex differentiation	Dmrt1	IMP		Mouse	MGI:MGI:4839662|PMID:20951351
Biological Process	GO:0007127	meiosis I	Dmrt1	IMP	MGI:MGI:2385912	Mouse	PMID:21621532
Biological Process	GO:0045835	negative regulation of meiotic nuclear division	Dmrt1	IMP		Mouse	MGI:MGI:4839662|PMID:20951351
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Dmrt1	IDA		Mouse	MGI:MGI:4839662|PMID:20951351
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Dmrt1	IDA		Mouse	MGI:MGI:4818833|PMID:20616082
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Dmrt1	IDA		Mouse	MGI:MGI:4420727|PMID:20007774
Biological Process	GO:0048599	oocyte development	Dmrt1	IMP	MGI:MGI:2385912	Mouse	PMID:21621532
Biological Process	GO:2000020	positive regulation of male gonad development	Dmrt1	IMP	MGI:MGI:2385911	Mouse	PMID:21775990
Biological Process	GO:0060903	positive regulation of meiosis I	Dmrt1	IMP	MGI:MGI:2385912	Mouse	PMID:21621532
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	Dmrt1	IMP		Mouse	MGI:MGI:4839662|PMID:20951351
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Dmrt1	IDA		Mouse	MGI:MGI:4818833|PMID:20616082
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Dmrt1	IDA		Mouse	MGI:MGI:5474771|PMID:17605809
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Dmrt1	IDA		Mouse	MGI:MGI:4839662|PMID:20951351
Biological Process	GO:1900107	regulation of nodal signaling pathway	Dmrt1	IMP		Mouse	PMID:23473982
Biological Process	GO:0060009	Sertoli cell development	Dmrt1	IMP	MGI:MGI:2385911	Mouse	PMID:21775990
Biological Process	GO:0060008	Sertoli cell differentiation	Dmrt1	IMP		Mouse	MGI:MGI:1926717|PMID:11040213
Biological Process	GO:0060008	Sertoli cell differentiation	Dmrt1	IMP	MGI:MGI:2385911	Mouse	PMID:17540358
Biological Process	GO:0060008	Sertoli cell differentiation	Dmrt1	IMP	MGI:MGI:2385912	Mouse	PMID:17540358
Biological Process	GO:0007283	spermatogenesis	Dmrt1	IMP	MGI:MGI:2385912	Mouse	PMID:17540358
Biological Process	GO:0007283	spermatogenesis	Dmrt1	IMP	MGI:MGI:2385911	Mouse	PMID:17540358

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern