Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DMRT2
  • Mouse genes Dmrt2
  • Rat genes Dmrt2
  • Zfish genes dmrt2a,dmrt2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dmrt2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	dmrt2b	IDA		Zfish	PMID:18358846
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Dmrt2	IMP		Mouse	MGI:MGI:3820487|PMID:17974128
Molecular Function	GO:0003700	DNA-binding transcription factor activity	dmrt2b	IDA		Zfish	PMID:18358846
Molecular Function	GO:0042802	identical protein binding	Dmrt2	IPI	PR:Q8BG36	Mouse	PMID:17605809
Molecular Function	GO:0005515	protein binding	DMRT2	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DMRT2	IPI	UniProtKB:Q9Y5V3	Human	PMID:32296183
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Dmrt2	IDA		Mouse	MGI:MGI:5474771|PMID:17605809
Molecular Function	GO:0043565	sequence-specific DNA binding	Dmrt2	IDA		Mouse	PMID:17605809
Cellular Component	GO:0005634	nucleus	dmrt2a	IDA		Zfish	PMID:10021344|ZFIN:ZDB-PUB-990428-2
Biological Process	GO:0006915	apoptotic process	dmrt2a	IDA		Zfish	PMID:10021344
Biological Process	GO:0007368	determination of left/right symmetry	dmrt2b	IMP	ZFIN:ZDB-MRPHLNO-091030-2,ZFIN:ZDB-MRPHLNO-091030-3	Zfish	PMID:19789708
Biological Process	GO:0007368	determination of left/right symmetry	dmrt2a	IMP	ZFIN:ZDB-MRPHLNO-070815-2	Zfish	PMID:16136187
Biological Process	GO:0007368	determination of left/right symmetry	dmrt2a	IMP	ZFIN:ZDB-MRPHLNO-070815-1	Zfish	PMID:22899848
Biological Process	GO:0007368	determination of left/right symmetry	dmrt2a	IMP	ZFIN:ZDB-MRPHLNO-070815-1	Zfish	PMID:16136187
Biological Process	GO:0006351	DNA-templated transcription	dmrt2b	IDA		Zfish	PMID:18358846|ZFIN:ZDB-PUB-080327-12
Biological Process	GO:0048706	embryonic skeletal system development	Dmrt2	IMP	MGI:MGI:3512139	Mouse	PMID:16387292
Biological Process	GO:0055001	muscle cell development	dmrt2b	IMP	ZFIN:ZDB-MRPHLNO-091030-2,ZFIN:ZDB-MRPHLNO-091030-3	Zfish	PMID:19789708
Biological Process	GO:0061055	myotome development	Dmrt2	IMP	MGI:MGI:3512139	Mouse	PMID:16387292
Biological Process	GO:0060037	pharyngeal system development	dmrt2b	IMP	ZFIN:ZDB-GENO-190916-11	Zfish	PMID:30341107
Biological Process	GO:0060037	pharyngeal system development	dmrt2b	IMP	ZFIN:ZDB-MRPHLNO-190514-1	Zfish	PMID:30341107
Biological Process	GO:2000287	positive regulation of myotome development	Dmrt2	IMP	MGI:MGI:3512139	Mouse	PMID:16387292
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Dmrt2	IMP		Mouse	MGI:MGI:3820487|PMID:17974128
Biological Process	GO:0006355	regulation of DNA-templated transcription	dmrt2b	IDA		Zfish	PMID:18358846|ZFIN:ZDB-PUB-080327-12
Biological Process	GO:0014807	regulation of somitogenesis	Dmrt2	IMP	MGI:MGI:3512139	Mouse	PMID:17974128
Biological Process	GO:0014807	regulation of somitogenesis	Dmrt2	IGI	MGI:MGI:97487	Mouse	PMID:17974128
Biological Process	GO:0048741	skeletal muscle fiber development	dmrt2a	IGI	ZFIN:ZDB-MIRNAG-041217-2	Zfish	PMID:28483596
Biological Process	GO:0001756	somitogenesis	dmrt2b	IMP	ZFIN:ZDB-MRPHLNO-091030-2,ZFIN:ZDB-MRPHLNO-091030-3	Zfish	PMID:19789708

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern