Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DMRTA2
  • Mouse genes Dmrta2
  • Rat genes Dmrta2
  • Zfish genes dmrta2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dmrta2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Dmrta2	IPI	PR:A2A9A2	Mouse	PMID:17605809
Molecular Function	GO:0005515	protein binding	Dmrta2	IPI	PR:Q9QZ59	Mouse	PMID:17605809
Molecular Function	GO:0043565	sequence-specific DNA binding	Dmrta2	IDA		Mouse	PMID:17605809
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	DMRTA2	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Dmrta2	IDA		Mouse	PMID:23056351
Biological Process	GO:0021796	cerebral cortex regionalization	Dmrta2	IMP	MGI:MGI:5527461	Mouse	PMID:23056351
Biological Process	GO:0021796	cerebral cortex regionalization	Dmrta2	IMP		Mouse	PMID:22923088
Biological Process	GO:0060128	corticotropin hormone secreting cell differentiation	dmrta2	IMP	ZFIN:ZDB-MRPHLNO-150216-1,ZFIN:ZDB-MRPHLNO-150216-2	Zfish	PMID:25489906
Biological Process	GO:0071542	dopaminergic neuron differentiation	Dmrta2	IMP		Mouse	PMID:21576465
Biological Process	GO:0007405	neuroblast proliferation	Dmrta2	IMP	MGI:MGI:5527461	Mouse	PMID:23056351
Biological Process	GO:0048665	neuron fate specification	Dmrta2	IMP		Mouse	PMID:21576465
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Dmrta2	IMP	MGI:MGI:5527461	Mouse	PMID:23056351
Biological Process	GO:0035914	skeletal muscle cell differentiation	Dmrta2	IMP		Mouse	PMID:22147266
Biological Process	GO:0048863	stem cell differentiation	Dmrta2	IMP		Mouse	PMID:21576465
Biological Process	GO:0048866	stem cell fate specification	Dmrta2	IMP		Mouse	PMID:21576465
Biological Process	GO:0021537	telencephalon development	dmrta2	IMP	ZFIN:ZDB-GENO-121012-1	Zfish	PMID:22023386

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern