Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DNAJA1
  • Mouse genes Dnaja1
  • Rat genes Dnaja1
  • Zfish genes dnaja1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnaja1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001671	ATPase activator activity	DNAJA1	IDA		Human	PMID:24318877
Molecular Function	GO:0001671	ATPase activator activity	Dnaja1	IDA		Rat	PMID:9605323|RGD:633115
Molecular Function	GO:0055131	C3HC4-type RING finger domain binding	DNAJA1	IPI	UniProtKB:Q6ZRF8	Human	PMID:25281747
Molecular Function	GO:0001664	G protein-coupled receptor binding	DNAJA1	IPI	UniProtKB:O15354	Human	PMID:12150907
Molecular Function	GO:0030544	Hsp70 protein binding	DNAJA1	IDA		Human	PMID:14752510
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	DNAJA1	IDA		Human	PMID:15082773
Molecular Function	GO:0005515	protein binding	DNAJA1	IPI	UniProtKB:Q9GZX7	Human	PMID:22085931
Molecular Function	GO:0005515	protein binding	DNAJA1	IPI	UniProtKB:P56696	Human	PMID:23431407
Molecular Function	GO:0005515	protein binding	DNAJA1	IPI	UniProtKB:P42858	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	DNAJA1	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DNAJA1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Dnaja1	IPI	UniProtKB:Q07813	Mouse	MGI:MGI:5784990|PMID:14752510
Molecular Function	GO:0005515	protein binding	Dnaja1	IPI	RGD:68359	Rat	PMID:9915854|RGD:2303787
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJA1	IDA		Human	PMID:14752510
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJA1	IPI	UniProtKB:P0DMV8	Human	PMID:21231916
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJA1	IPI	UniProtKB:P0DMV9	Human	PMID:21231916
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJA1	IPI	UniProtKB:P17066	Human	PMID:21231916
Molecular Function	GO:0030957	Tat protein binding	DNAJA1	IPI	UniProtKB:Q07813	Human	PMID:14752510
Molecular Function	GO:0031625	ubiquitin protein ligase binding	DNAJA1	IPI	UniProtKB:O60260	Human	PMID:12150907
Cellular Component	GO:0005829	cytosol	DNAJA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	DNAJA1	IDA		Human	PMID:21231916
Cellular Component	GO:0070062	extracellular exosome	DNAJA1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	DNAJA1	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	DNAJA1	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	DNAJA1	IDA		Human	PMID:21231916
Cellular Component	GO:0015630	microtubule cytoskeleton	DNAJA1	IDA		Human	GO_REF:0000052
Biological Process	GO:0030521	androgen receptor signaling pathway	Dnaja1	IMP	MGI:MGI:3573790	Mouse	PMID:15660130
Biological Process	GO:0030317	flagellated sperm motility	Dnaja1	IMP	MGI:MGI:3573790	Mouse	PMID:15660130
Biological Process	GO:0043066	negative regulation of apoptotic process	DNAJA1	IMP		Human	PMID:14752510
Biological Process	GO:1903748	negative regulation of establishment of protein localization to mitochondrion	DNAJA1	IDA		Human	PMID:14752510
Biological Process	GO:0043508	negative regulation of JUN kinase activity	DNAJA1	IMP		Human	PMID:24512202
Biological Process	GO:1905259	negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	DNAJA1	IDA		Human	PMID:14752510
Biological Process	GO:0031397	negative regulation of protein ubiquitination	DNAJA1	IDA		Human	PMID:12150907
Biological Process	GO:0043065	positive regulation of apoptotic process	DNAJA1	IMP		Human	PMID:24512202
Biological Process	GO:0070585	protein localization to mitochondrion	DNAJA1	IMP		Human	PMID:14752510
Biological Process	GO:0051223	regulation of protein transport	DNAJA1	IDA		Human	PMID:14752510
Biological Process	GO:0007283	spermatogenesis	Dnaja1	IMP	MGI:MGI:3573790	Mouse	PMID:15660130
Biological Process	GO:1901998	toxin transport	Dnaja1	IMP		Mouse	PMID:23716698

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern