Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DNAJA3
  • Mouse genes Dnaja3
  • Rat genes Dnaja3
  • Zfish genes dnaja3a,dnaja3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnaja3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030695	GTPase regulator activity	Dnaja3	IDA		Mouse	PMID:11116152
Molecular Function	GO:0030544	Hsp70 protein binding	Dnaja3	IPI	RGD:1311806	Rat	PMID:15030183|RGD:6784522
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:P38646	Human	PMID:10411904
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:Q61115	Human	PMID:17230190
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:O15169	Human	PMID:17588722
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:P25054	Human	PMID:17588722
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:Q9NR80	Human	PMID:17588722
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:P42232	Human	PMID:21106534
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:P51692	Human	PMID:21106534
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:P08581	Human	PMID:21242965
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:O60341	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:Q86X55	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:Q96LA8	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DNAJA3	IPI	UniProtKB:P08581	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	Dnaja3	IPI	PR:P54099	Mouse	PMID:16327803
Molecular Function	GO:0005515	protein binding	Dnaja3	IPI	PR:P38647	Mouse	PMID:14993262
Molecular Function	GO:0005515	protein binding	Dnaja3	IPI	UniProtKB:P38646	Mouse	PMID:16327803
Molecular Function	GO:0030971	receptor tyrosine kinase binding	Dnaja3	IPI	UniProtKB:Q61006	Mouse	MGI:MGI:3835221|PMID:19038220
Molecular Function	GO:0051082	unfolded protein binding	Dnaja3	IPI	UniProtKB:Q61698	Mouse	PMID:11116152
Cellular Component	GO:0005884	actin filament	DNAJA3	IDA		Human	PMID:17588722
Cellular Component	GO:0005829	cytosol	Dnaja3	IDA		Mouse	MGI:MGI:3835221|PMID:19038220
Cellular Component	GO:0005829	cytosol	Dnaja3	IDA		Mouse	PMID:11116152
Cellular Component	GO:0019897	extrinsic component of plasma membrane	Dnaja3	IDA		Mouse	MGI:MGI:3835221|PMID:19038220
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	DNAJA3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005759	mitochondrial matrix	DNAJA3	IDA		Human	PMID:11719219
Cellular Component	GO:0005739	mitochondrion	DNAJA3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	DNAJA3	IDA		Human	PMID:20053669
Cellular Component	GO:0005739	mitochondrion	DNAJA3	IDA		Human	PMID:21231916
Cellular Component	GO:0005739	mitochondrion	Dnaja3	IDA		Mouse	PMID:11116152
Cellular Component	GO:0005739	mitochondrion	Dnaja3	IMP	MGI:MGI:3040718	Mouse	PMID:14993262
Cellular Component	GO:0005739	mitochondrion	Dnaja3	IDA		Mouse	PMID:16327803
Cellular Component	GO:0005739	mitochondrion	Dnaja3	HDA		Mouse	PMID:18614015
Cellular Component	GO:0031594	neuromuscular junction	Dnaja3	IDA		Mouse	MGI:MGI:3835221|PMID:19038220
Cellular Component	GO:0005634	nucleus	Dnaja3	IDA		Mouse	PMID:11116152
Cellular Component	GO:0045211	postsynaptic membrane	Dnaja3	IDA		Mouse	MGI:MGI:3835221|PMID:19038220
Biological Process	GO:0006924	activation-induced cell death of T cells	Dnaja3	IMP	MGI:MGI:2448686,MGI:MGI:3040717	Mouse	PMID:15879105
Biological Process	GO:0006915	apoptotic process	Dnaja3	IMP	MGI:MGI:2182091,MGI:MGI:3040717	Mouse	PMID:16327803
Biological Process	GO:0090398	cellular senescence	Dnaja3	IDA		Mouse	PMID:15572682
Biological Process	GO:0009790	embryo development	Dnaja3	IMP	MGI:MGI:3040718	Mouse	PMID:14993262
Biological Process	GO:0009790	embryo development	Dnaja3	IMP	MGI:MGI:2182091,MGI:MGI:3040717	Mouse	PMID:16327803
Biological Process	GO:0006264	mitochondrial DNA replication	Dnaja3	IMP	MGI:MGI:2182091,MGI:MGI:3040717	Mouse	PMID:16327803
Biological Process	GO:0007005	mitochondrion organization	Dnaja3	IMP	MGI:MGI:2182091,MGI:MGI:3040717	Mouse	PMID:16327803
Biological Process	GO:0008285	negative regulation of cell population proliferation	DNAJA3	IDA		Human	PMID:11719219
Biological Process	GO:0043069	negative regulation of programmed cell death	Dnaja3	IMP	MGI:MGI:3040718	Mouse	PMID:14993262
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	DNAJA3	IDA		Human	PMID:21106534
Biological Process	GO:0007528	neuromuscular junction development	Dnaja3	IMP		Mouse	MGI:MGI:3835221|PMID:19038220
Biological Process	GO:0042102	positive regulation of T cell proliferation	Dnaja3	IMP	MGI:MGI:2448686,MGI:MGI:3040717	Mouse	PMID:15879105
Biological Process	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	Dnaja3	IMP		Mouse	MGI:MGI:3835221|PMID:19038220
Biological Process	GO:0007264	small GTPase mediated signal transduction	Dnaja3	IDA		Mouse	PMID:11116152
Biological Process	GO:0033077	T cell differentiation in thymus	Dnaja3	IMP	MGI:MGI:2448686,MGI:MGI:3040717	Mouse	PMID:15879105

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern