Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DNAJB1
  • Mouse genes Dnajb1
  • Rat genes Dnajb1
  • Zfish genes dnajb1a,dnajb1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnajb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001671	ATPase activator activity	DNAJB1	IDA		Human	PMID:20060297
Molecular Function	GO:0001671	ATPase activator activity	DNAJB1	IDA		Human	PMID:23921388
Molecular Function	GO:0001671	ATPase activator activity	DNAJB1	IDA		Human	PMID:24318877
Molecular Function	GO:0051117	ATPase binding	DNAJB1	IPI	UniProtKB:P0DMV8|UniProtKB:P0DMV9	Human	PMID:23921388
Molecular Function	GO:0045296	cadherin binding	DNAJB1	HDA		Human	PMID:25468996
Molecular Function	GO:0030544	Hsp70 protein binding	DNAJB1	IPI	UniProtKB:P0DMV8|UniProtKB:P0DMV9	Human	PMID:23921388
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:Q62392	Human	PMID:17024176
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:P11142	Human	PMID:23921388
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:Q9UNF1	Human	PMID:27120771
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:Q14166	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:Q14166	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:O60907-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:P13051-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:P19544-6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:Q03403	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:Q06547-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:Q06547-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:Q6P4D5-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DNAJB1	IPI	UniProtKB:Q00613	Human	PMID:9499401
Molecular Function	GO:0044183	protein folding chaperone	Dnajb1	IDA		Mouse	MGI:MGI:6316406|PMID:27496612
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJB1	IPI	UniProtKB:P0DMV8	Human	PMID:21231916
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJB1	IPI	UniProtKB:P0DMV9	Human	PMID:21231916
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJB1	IPI	UniProtKB:P17066	Human	PMID:21231916
Molecular Function	GO:0003714	transcription corepressor activity	DNAJB1	IDA		Human	PMID:9499401
Molecular Function	GO:0140416	transcription regulator inhibitor activity	DNAJB1	IDA		Human	PMID:9499401
Molecular Function	GO:0051082	unfolded protein binding	DNAJB1	IDA		Human	PMID:21231916
Cellular Component	GO:0005737	cytoplasm	DNAJB1	IDA		Human	PMID:25468996
Cellular Component	GO:0005829	cytosol	DNAJB1	IDA		Human	PMID:21231916
Cellular Component	GO:0043197	dendritic spine	Dnajb1	IDA		Rat	PMID:9878698|RGD:10059325
Cellular Component	GO:0070062	extracellular exosome	DNAJB1	HDA		Human	PMID:19056867
Cellular Component	GO:0098978	glutamatergic synapse	Dnajb1	IDA		Rat	PMID:9878698|RGD:10059325
Cellular Component	GO:0043025	neuronal cell body	Dnajb1	IDA		Rat	PMID:9878698|RGD:10059325
Cellular Component	GO:0005654	nucleoplasm	DNAJB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DNAJB1	HDA		Human	PMID:21630459
Cellular Component	GO:0098794	postsynapse	Dnajb1	IDA		Rat	PMID:9878698|RGD:10059325
Cellular Component	GO:0014069	postsynaptic density	Dnajb1	IDA		Rat	PMID:9878698|RGD:10059325
Cellular Component	GO:0061827	sperm head	Dnajb1	IDA		Rat	PMID:16955402|RGD:13506945
Biological Process	GO:0034605	cellular response to heat	DNAJB1	IDA		Human	PMID:9499401
Biological Process	GO:0051085	chaperone cofactor-dependent protein refolding	DNAJB1	IDA		Human	PMID:18620420
Biological Process	GO:0051085	chaperone cofactor-dependent protein refolding	Dnajb1	IGI	MGI:MGI:105384	Mouse	PMID:14644449
Biological Process	GO:0030900	forebrain development	Dnajb1	IEP		Rat	PMID:9878698|RGD:10059325
Biological Process	GO:0002088	lens development in camera-type eye	dnajb1b	IMP	ZFIN:ZDB-MRPHLNO-160726-5	Zfish	PMID:27218149
Biological Process	GO:0002088	lens development in camera-type eye	dnajb1b	IMP	ZFIN:ZDB-MRPHLNO-160726-6	Zfish	PMID:27218149
Biological Process	GO:0002088	lens development in camera-type eye	dnajb1a	IMP	ZFIN:ZDB-MRPHLNO-160726-4	Zfish	PMID:27218149
Biological Process	GO:0090084	negative regulation of inclusion body assembly	DNAJB1	IDA		Human	PMID:21231916
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	DNAJB1	IDA		Human	PMID:9499401
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	DNAJB1	IDA		Human	PMID:23921388
Biological Process	GO:0006457	protein folding	Dnajb1	IDA		Mouse	MGI:MGI:6316406|PMID:27496612

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern