Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DNAJB2
  • Mouse genes Dnajb2
  • Rat genes Dnajb2
  • Zfish genes dnajb2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnajb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001671	ATPase activator activity	DNAJB2	IDA		Human	PMID:22219199
Molecular Function	GO:0001671	ATPase activator activity	DNAJB2	IDA		Human	PMID:7957263
Molecular Function	GO:0030544	Hsp70 protein binding	DNAJB2	IPI	UniProtKB:P0DMV8	Human	PMID:22219199
Molecular Function	GO:0005515	protein binding	DNAJB2	IPI	UniProtKB:P25686-2	Human	PMID:21625540
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJB2	IPI	UniProtKB:P0DMV8	Human	PMID:21231916
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJB2	IPI	UniProtKB:P0DMV9	Human	PMID:21231916
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJB2	IPI	UniProtKB:P17066	Human	PMID:21231916
Molecular Function	GO:0043130	ubiquitin binding	DNAJB2	IDA		Human	PMID:28031292
Molecular Function	GO:0140036	ubiquitin-dependent protein binding	DNAJB2	IDA		Human	PMID:28031292
Molecular Function	GO:0051082	unfolded protein binding	DNAJB2	IDA		Human	PMID:21231916
Molecular Function	GO:0051082	unfolded protein binding	DNAJB2	IDA		Human	PMID:24023695
Cellular Component	GO:0005829	cytosol	DNAJB2	IDA		Human	PMID:21231916
Cellular Component	GO:0031965	nuclear membrane	DNAJB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DNAJB2	IDA		Human	PMID:21231916
Biological Process	GO:0061077	chaperone-mediated protein folding	DNAJB2	IMP		Human	PMID:24023695
Biological Process	GO:0030308	negative regulation of cell growth	DNAJB2	IGI	UniProtKB:P0DMV8	Human	PMID:9553041
Biological Process	GO:0030308	negative regulation of cell growth	DNAJB2	IGI	UniProtKB:P0DMV9	Human	PMID:9553041
Biological Process	GO:0008285	negative regulation of cell population proliferation	DNAJB2	IGI	UniProtKB:P0DMV8	Human	PMID:9553041
Biological Process	GO:0008285	negative regulation of cell population proliferation	DNAJB2	IGI	UniProtKB:P0DMV9	Human	PMID:9553041
Biological Process	GO:0090084	negative regulation of inclusion body assembly	DNAJB2	IDA		Human	PMID:21231916
Biological Process	GO:0032091	negative regulation of protein binding	DNAJB2	IDA		Human	PMID:7957263
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	DNAJB2	IDA		Human	PMID:22219199
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	DNAJB2	IDA		Human	PMID:7957263
Biological Process	GO:0042026	protein refolding	DNAJB2	IDA		Human	PMID:21231916
Biological Process	GO:1903644	regulation of chaperone-mediated protein folding	DNAJB2	IDA		Human	PMID:7957263
Biological Process	GO:0031396	regulation of protein ubiquitination	DNAJB2	IMP		Human	PMID:24023695

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern