Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DNASE1L3
  • Mouse genes Dnase1l3
  • Rat genes Dnase1l3
  • Zfish genes dnase1l1l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnase1l3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Dnase1l3	IDA		Rat	PMID:9665719|RGD:728743
Molecular Function	GO:0004520	DNA endonuclease activity	Dnase1l3	IDA		Rat	PMID:9665719|RGD:728743
Molecular Function	GO:0004519	endonuclease activity	Dnase1l3	IDA		Mouse	PMID:12050166
Molecular Function	GO:0005515	protein binding	DNASE1L3	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DNASE1L3	IPI	UniProtKB:P26371	Human	PMID:32296183
Cellular Component	GO:0005783	endoplasmic reticulum	DNASE1L3	IDA		Human	PMID:23229555
Cellular Component	GO:0005634	nucleus	DNASE1L3	IDA		Human	PMID:23229555
Cellular Component	GO:0005634	nucleus	Dnase1l3	IDA		Mouse	PMID:12050166
Cellular Component	GO:0005634	nucleus	Dnase1l3	IDA		Rat	PMID:9665719|RGD:728743
Biological Process	GO:0006309	apoptotic DNA fragmentation	DNASE1L3	IDA		Human	PMID:23229555
Biological Process	GO:0006309	apoptotic DNA fragmentation	Dnase1l3	IDA		Mouse	PMID:12050166
Biological Process	GO:0006308	DNA catabolic process	Dnase1l3	IDA		Mouse	MGI:MGI:6094744|PMID:29191910
Biological Process	GO:0002088	lens development in camera-type eye	dnase1l1l	IMP	ZFIN:ZDB-MRPHLNO-150216-4	Zfish	PMID:25127661
Biological Process	GO:0070306	lens fiber cell differentiation	dnase1l1l	IMP	ZFIN:ZDB-GENO-210325-46	Zfish	PMID:32061775
Biological Process	GO:0002283	neutrophil activation involved in immune response	Dnase1l3	IDA		Mouse	MGI:MGI:6094744|PMID:29191910
Biological Process	GO:0010623	programmed cell death involved in cell development	Dnase1l3	IDA		Mouse	PMID:12050166
Biological Process	GO:0002673	regulation of acute inflammatory response	Dnase1l3	IDA		Mouse	MGI:MGI:6094744|PMID:29191910
Biological Process	GO:0070948	regulation of neutrophil mediated cytotoxicity	Dnase1l3	IDA		Mouse	MGI:MGI:6094744|PMID:29191910
Biological Process	GO:0060041	retina development in camera-type eye	dnase1l1l	IMP	ZFIN:ZDB-MRPHLNO-150216-4	Zfish	PMID:25127661

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern