Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DNASE2
  • Mouse genes Dnase2a
  • Rat genes Dnase2
  • Zfish genes dnase2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnase2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004531	deoxyribonuclease II activity	Dnase2a	IDA		Mouse	PMID:11375492
Molecular Function	GO:0004520	DNA endonuclease activity	Dnase2	IDA		Rat	PMID:10558878|RGD:70721
Cellular Component	GO:0070062	extracellular exosome	DNASE2	HDA		Human	PMID:23533145
Biological Process	GO:0006308	DNA catabolic process	Dnase2a	IMP	MGI:MGI:2449811	Mouse	PMID:18991290
Biological Process	GO:0006308	DNA catabolic process	Dnase2a	IMP	MGI:MGI:2449811	Mouse	PMID:15568025
Biological Process	GO:0043353	enucleate erythrocyte differentiation	Dnase2a	IMP	MGI:MGI:2449811	Mouse	PMID:11375492
Biological Process	GO:0050776	regulation of immune response	Dnase2a	IGI	MGI:MGI:2442261	Mouse	PMID:26371324

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern