Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DND1
  • Mouse genes Dnd1
  • Rat genes Dnd1
  • Zfish genes dnd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003730	mRNA 3'-UTR binding	DND1	IDA		Human	PMID:18155131
Molecular Function	GO:0003730	mRNA 3'-UTR binding	dnd1	IDA		Zfish	PMID:20587335
Molecular Function	GO:0003729	mRNA binding	dnd1	IDA		Zfish	PMID:20587335
Molecular Function	GO:0005515	protein binding	DND1	IPI	UniProtKB:Q6ZRY4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Dnd1	IPI	UniProtKB:Q99J72	Mouse	MGI:MGI:3796258|PMID:18509452
Molecular Function	GO:0003723	RNA binding	dnd1	IPI	ZFIN:ZDB-GENE-010621-1	Zfish	PMID:22705393
Molecular Function	GO:0003723	RNA binding	dnd1	IPI	ZFIN:ZDB-GENE-030131-8207	Zfish	PMID:22705393
Cellular Component	GO:0005737	cytoplasm	DND1	IDA		Human	PMID:18155131
Cellular Component	GO:0005737	cytoplasm	Dnd1	IDA		Mouse	MGI:MGI:3796258|PMID:18509452
Cellular Component	GO:0043073	germ cell nucleus	dnd1	IDA		Zfish	PMID:19013519
Cellular Component	GO:0005654	nucleoplasm	DND1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DND1	IDA		Human	PMID:18155131
Cellular Component	GO:0043186	P granule	dnd1	IDA		Zfish	PMID:19013519
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	DND1	IDA		Human	PMID:28297718
Biological Process	GO:0007281	germ cell development	Dnd1	IMP	MGI:MGI:2158668	Mouse	PMID:15902260
Biological Process	GO:0007281	germ cell development	Dnd1	IMP		Rat	PMID:22655094|RGD:40924659
Biological Process	GO:0007281	germ cell development	dnd1	IMP	ZFIN:ZDB-MRPHLNO-050413-1	Zfish	PMID:16129886
Biological Process	GO:0007281	germ cell development	dnd1	IMP	ZFIN:ZDB-MRPHLNO-050413-1	Zfish	PMID:15728735
Biological Process	GO:0008354	germ cell migration	dnd1	IMP	ZFIN:ZDB-MRPHLNO-050413-1	Zfish	PMID:26510515
Biological Process	GO:0008354	germ cell migration	dnd1	IMP	ZFIN:ZDB-MRPHLNO-050413-1	Zfish	PMID:16129886
Biological Process	GO:0008354	germ cell migration	dnd1	IMP	ZFIN:ZDB-MRPHLNO-050413-1	Zfish	PMID:12932328
Biological Process	GO:0060047	heart contraction	dnd1	IMP	ZFIN:ZDB-MRPHLNO-050413-1	Zfish	PMID:19064678
Biological Process	GO:0048255	mRNA stabilization	dnd1	IMP	ZFIN:ZDB-MRPHLNO-050413-1	Zfish	PMID:18155131
Biological Process	GO:0060965	negative regulation of miRNA-mediated gene silencing	DND1	IDA		Human	PMID:18155131
Biological Process	GO:0010628	positive regulation of gene expression	dnd1	IDA		Zfish	PMID:20587335
Biological Process	GO:2000145	regulation of cell motility	dnd1	IMP	ZFIN:ZDB-MRPHLNO-050413-1	Zfish	PMID:22705393
Biological Process	GO:2000145	regulation of cell motility	dnd1	IGI	ZFIN:ZDB-MRPHLNO-050413-1,ZFIN:ZDB-MRPHLNO-120823-1,ZFIN:ZDB-MRPHLNO-120823-2,ZFIN:ZDB-MRPHLNO-120823-3,ZFIN:ZDB-MRPHLNO-120823-4,ZFIN:ZDB-MRPHLNO-120823-5	Zfish	PMID:22705393
Biological Process	GO:0007283	spermatogenesis	Dnd1	IMP		Rat	PMID:22655094|RGD:40924659

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern