Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Dnm3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes DNM3
- Mouse genes Dnm3
- Rat genes Dnm3
- Zfish genes dnm3a,dnm3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnm3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003924	GTPase activity	Dnm3	IMP		Rat	PMID:17880892\|RGD:8553820
Molecular Function	GO:0050998	nitric-oxide synthase binding	Dnm3	IDA		Rat	PMID:21490139\|RGD:5131889
Molecular Function	GO:0005515	protein binding	DNM3	IPI	UniProtKB:Q96RU3	Human	PMID:15252009
Molecular Function	GO:0005515	protein binding	Dnm3	IPI	UniProtKB:Q7TQF7	Mouse	MGI:MGI:5644011\|PMID:23640057
Molecular Function	GO:0005515	protein binding	Dnm3	IPI	PR:P39053	Mouse	PMID:23746204
Molecular Function	GO:0005515	protein binding	Dnm3	IPI	RGD:619839	Rat	PMID:15741233\|RGD:8554738
Molecular Function	GO:0005515	protein binding	Dnm3	IPI	UniProtKB:Q66HL2	Rat	PMID:15741233\|RGD:8554738
Molecular Function	GO:0005515	protein binding	Dnm3	IPI	RGD:620705	Rat	PMID:17880892\|RGD:8553820
Molecular Function	GO:0005515	protein binding	Dnm3	IPI	RGD:628725	Rat	PMID:17880892\|RGD:8553820
Molecular Function	GO:0005515	protein binding	Dnm3	IPI	UniProtKB:Q9Z214	Rat	PMID:17880892\|RGD:8553820
Molecular Function	GO:0005515	protein binding	Dnm3	IPI	RGD:1549750	Rat	PMID:23994472\|RGD:9685166
Molecular Function	GO:0120283	protein serine/threonine kinase binding	Dnm3	IPI	RGD:620760	Rat	PMID:20802490\|RGD:152995511
Molecular Function	GO:0099186	structural constituent of postsynapse	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Molecular Function	GO:0099186	structural constituent of postsynapse	Dnm3	IMP		Rat	PMID:17880892\|RGD:8553820
Molecular Function	GO:0031798	type 1 metabotropic glutamate receptor binding	Dnm3	IPI	RGD:2742	Rat	PMID:17880892\|RGD:8553820
Molecular Function	GO:0031802	type 5 metabotropic glutamate receptor binding	Dnm3	IPI	RGD:2746	Rat	PMID:17880892\|RGD:8553820
Cellular Component	GO:0061828	apical tubulobulbar complex	Dnm3	IDA		Rat	PMID:17133358\|RGD:8553356
Cellular Component	GO:0030424	axon	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Cellular Component	GO:0061829	basal tubulobulbar complex	Dnm3	IDA		Rat	PMID:17133358\|RGD:8553356
Cellular Component	GO:0005737	cytoplasm	Dnm3	IDA		Rat	PMID:9725914\|RGD:9685132
Cellular Component	GO:0043197	dendritic spine	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Cellular Component	GO:0044327	dendritic spine head	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Cellular Component	GO:0070062	extracellular exosome	DNM3	HDA		Human	PMID:23533145
Cellular Component	GO:0098978	glutamatergic synapse	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Cellular Component	GO:0098978	glutamatergic synapse	Dnm3	IMP		Rat	PMID:17880892\|RGD:8553820
Cellular Component	GO:0005794	Golgi apparatus	Dnm3	IDA		Rat	PMID:9725914\|RGD:9685132
Cellular Component	GO:0005739	mitochondrion	Dnm3	HDA		Mouse	PMID:14651853
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Dnm3	IDA		Rat	PMID:15126636\|RGD:8554781
Cellular Component	GO:0001917	photoreceptor inner segment	Dnm3	IDA		Mouse	PMID:23746204
Cellular Component	GO:0014069	postsynaptic density	Dnm3	IDA		Rat	PMID:12646135\|RGD:8554278
Cellular Component	GO:0014069	postsynaptic density	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Cellular Component	GO:0098844	postsynaptic endocytic zone membrane	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Cellular Component	GO:0098844	postsynaptic endocytic zone membrane	Dnm3	IMP		Rat	PMID:17880892\|RGD:8553820
Cellular Component	GO:0098793	presynapse	Dnm3	IDA		Mouse	PMID:21689597
Cellular Component	GO:0045202	synapse	Dnm3	IDA		Mouse	MGI:MGI:5285027\|PMID:21689597
Cellular Component	GO:0045202	synapse	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Cellular Component	GO:0043083	synaptic cleft	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Biological Process	GO:0006897	endocytosis	Dnm3	IMP		Rat	PMID:17880892\|RGD:8553820
Biological Process	GO:0046847	filopodium assembly	Dnm3	IDA		Rat	PMID:12646135\|RGD:8554278
Biological Process	GO:0046847	filopodium assembly	Dnm3	IDA		Rat	PMID:15741233\|RGD:8554738
Biological Process	GO:0061002	negative regulation of dendritic spine morphogenesis	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Biological Process	GO:0051491	positive regulation of filopodium assembly	Dnm3	IDA		Rat	PMID:17880892\|RGD:8553820
Biological Process	GO:1903423	positive regulation of synaptic vesicle recycling	Dnm3	IMP		Rat	PMID:23687302\|RGD:13462065
Biological Process	GO:0098884	postsynaptic neurotransmitter receptor internalization	Dnm3	IMP		Rat	PMID:17880892\|RGD:8553820
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	Dnm3	IMP		Rat	PMID:15741233\|RGD:8554738
Biological Process	GO:0007416	synapse assembly	Dnm3	IDA		Rat	PMID:15741233\|RGD:8554738
Biological Process	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane	Dnm3	IGI	UniProtKB:P39053	Mouse	MGI:MGI:5285027\|PMID:21689597
Biological Process	GO:0048488	synaptic vesicle endocytosis	Dnm3	IMP		Mouse	PMID:21689597
Biological Process	GO:0048488	synaptic vesicle endocytosis	Dnm3	IDA		Mouse	PMID:21689597

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.